Entry: PS00973

General information about the entry

Entry name [info] USP_2
Accession [info] PS00973
Entry type [info] PATTERN
Date [info] JUN-1994 (CREATED); DEC-2013 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU10093

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain signature 2.
Pattern [info]
[YMF]-x-[LK]-x-[SAGNC]-[LIVMFT]-x(2)-H-x-G-x(4,6)-G-H-[YF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 287 in 287 different sequences
Number of true positive hits 287 in 287 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 25
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.99 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 13
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
287 sequences

CREB_ASPCL  (A1CIL1    ), CREB_ASPFC  (B0Y4P5    ), CREB_ASPFN  (B8NSV5    ), 
CREB_ASPFU  (Q4WQI1    ), CREB_ASPNC  (A2Q9N1    ), CREB_ASPOR  (Q2UUG8    ), 
CREB_ASPTN  (Q0CT11    ), CREB_EMENI  (Q96V54    ), CREB_NEOFI  (A1CW53    ), 
FAF_DROME   (P55824    ), NOT_DROME   (Q9VVR1    ), U17L1_HUMAN (Q7RTZ2    ), 
U17L2_HUMAN (Q6R6M4    ), U17L3_HUMAN (A6NCW0    ), U17L5_HUMAN (A8MUK1    ), 
U17L6_HUMAN (Q6QN14    ), U17L7_HUMAN (P0C7H9    ), U17LA_HUMAN (C9JJH3    ), 
U17LB_HUMAN (C9JVI0    ), U17LD_HUMAN (C9JLJ4    ), U17LF_HUMAN (C9J2P7    ), 
U17LH_HUMAN (D6RBQ6    ), U17LI_HUMAN (D6R9N7    ), U17LJ_HUMAN (D6RCP7    ), 
U17LK_HUMAN (D6RJB6    ), U17LL_HUMAN (D6R901    ), U17LM_HUMAN (D6RA61    ), 
U17LO_HUMAN (Q0WX57    ), U17PA_MOUSE (Q61068    ), U17PB_MOUSE (E9Q9U0    ), 
U17PD_MOUSE (G5E8G2    ), U17PE_MOUSE (Q7M764    ), UB10A_XENLA (Q2NL57    ), 
UB10B_XENLA (Q7ZXR7    ), UB12A_XENLA (Q52KZ6    ), UB12B_XENLA (Q5M981    ), 
UB22A_XENLA (Q6GNI6    ), UB22B_XENLA (Q6DCJ1    ), UBP10_ARATH (Q9ZSB5    ), 
UBP10_BOVIN (A5PJS6    ), UBP10_HUMAN (Q14694    ), UBP10_MOUSE (P52479    ), 
UBP10_RAT   (Q3KR59    ), UBP10_XENTR (Q6DIJ4    ), UBP10_YEAST (P53874    ), 
UBP11_ARATH (Q9MAQ3    ), UBP11_CANLF (Q01988    ), UBP11_HUMAN (P51784    ), 
UBP11_MOUSE (Q99K46    ), UBP11_RAT   (Q5D006    ), UBP11_SCHPO (Q9UUD6    ), 
UBP11_YEAST (P36026    ), UBP12_ARATH (Q9FPT1    ), UBP12_BOVIN (A5D9H7    ), 
UBP12_DANRE (A4FUN7    ), UBP12_HUMAN (O75317    ), UBP12_MOUSE (Q9D9M2    ), 
UBP12_SALSA (C0HB46    ), UBP12_SCHPO (O60079    ), UBP12_YEAST (P39538    ), 
UBP13_ARATH (Q84WU2    ), UBP13_BOVIN (E1BMF7    ), UBP13_CHICK (E1BY77    ), 
UBP13_DANRE (F1QFS9    ), UBP13_HUMAN (Q92995    ), UBP13_MOUSE (Q5BKP2    ), 
UBP13_XENTR (F6V6I0    ), UBP13_YEAST (P38187    ), UBP14_ARATH (Q8L6Y1    ), 
UBP14_BOVIN (Q0IIF7    ), UBP14_CAEEL (Q17361    ), UBP14_HUMAN (P54578    ), 
UBP14_MOUSE (Q9JMA1    ), UBP14_PANTR (P60051    ), UBP14_RABIT (P40826    ), 
UBP14_SCHPO (Q11119    ), UBP14_YEAST (P38237    ), UBP15_BOVIN (Q2HJE4    ), 
UBP15_HUMAN (Q9Y4E8    ), UBP15_MOUSE (Q8R5H1    ), UBP15_RAT   (Q9R085    ), 
UBP15_XENTR (F6Z5C0    ), UBP15_YEAST (P50101    ), UBP16_BOVIN (Q08DA3    ), 
UBP16_DANRE (A8HAL1    ), UBP16_EMENI (P0CAQ1    ), UBP16_HUMAN (Q9Y5T5    ), 
UBP16_MACFA (Q4R6X7    ), UBP16_MOUSE (Q99LG0    ), UBP16_RAT   (Q2KJ09    ), 
UBP16_SCHPO (O74442    ), UBP16_XENLA (Q6PAW2    ), UBP16_XENTR (Q0VA64    ), 
UBP16_YEAST (Q02863    ), UBP18_HUMAN (Q9UMW8    ), UBP18_MOUSE (Q9WTV6    ), 
UBP18_PONAB (Q5RE63    ), UBP19_HUMAN (O94966    ), UBP19_MOUSE (Q3UJD6    ), 
UBP19_RAT   (Q6J1Y9    ), UBP1_ARATH  (Q9FPT5    ), UBP1_BOVIN  (Q29RP1    ), 
UBP1_HUMAN  (O94782    ), UBP1_MOUSE  (Q8BJQ2    ), UBP1_RAT    (Q569C3    ), 
UBP1_SCHPO  (Q9USM5    ), UBP1_YEAST  (P25037    ), UBP20_ARATH (Q9FPS7    ), 
UBP20_BOVIN (A7Z056    ), UBP20_DANRE (A5PN09    ), UBP20_HUMAN (Q9Y2K6    ), 
UBP20_MOUSE (Q8C6M1    ), UBP20_PONAB (Q5R5Z6    ), UBP20_XENLA (B1WBD7    ), 
UBP20_XENTR (A0JM59    ), UBP21_ARATH (Q9FIQ1    ), UBP21_BOVIN (Q2KJ72    ), 
UBP21_HUMAN (Q9UK80    ), UBP21_MOUSE (Q9QZL6    ), UBP21_RAT   (B2GUX4    ), 
UBP21_SCHPO (Q9UTT1    ), UBP22_BOVIN (P0C8Z3    ), UBP22_DANRE (A6H8I0    ), 
UBP22_HUMAN (Q9UPT9    ), UBP22_MOUSE (Q5DU02    ), UBP23_ARATH (Q9FPS4    ), 
UBP24_ARATH (Q9FPS3    ), UBP24_HUMAN (Q9UPU5    ), UBP24_MOUSE (B1AY13    ), 
UBP25_ARATH (Q9FPS2    ), UBP25_HUMAN (Q9UHP3    ), UBP25_MOUSE (P57080    ), 
UBP26_ARATH (Q9SCJ9    ), UBP26_HUMAN (Q9BXU7    ), UBP26_MOUSE (Q99MX1    ), 
UBP26_ORYSI (A2XDG4    ), UBP26_ORYSJ (A3AF13    ), UBP27_HUMAN (A6NNY8    ), 
UBP27_MOUSE (Q8CEG8    ), UBP28_CHICK (Q5ZID5    ), UBP28_HUMAN (Q96RU2    ), 
UBP28_MOUSE (Q5I043    ), UBP28_RAT   (D3ZJ96    ), UBP29_HUMAN (Q9HBJ7    ), 
UBP29_MOUSE (Q9ES63    ), UBP2_ARATH  (Q8W4N3    ), UBP2_BOVIN  (Q2KHV7    ), 
UBP2_CHICK  (O57429    ), UBP2_HUMAN  (O75604    ), UBP2_KLULA  (O42726    ), 
UBP2_MOUSE  (O88623    ), UBP2_RAT    (Q5U349    ), UBP2_SCHPO  (Q9P3U0    ), 
UBP2_YEAST  (Q01476    ), UBP30_DANRE (A2BGT0    ), UBP30_DROME (Q9W462    ), 
UBP30_HUMAN (Q70CQ3    ), UBP30_MOUSE (Q3UN04    ), UBP30_RAT   (D3ZPG5    ), 
UBP30_XENTR (A4QNN3    ), UBP31_HUMAN (Q70CQ4    ), UBP32_HUMAN (Q8NFA0    ), 
UBP33_BOVIN (A6QNM7    ), UBP33_DANRE (A5PMR2    ), UBP33_HUMAN (Q8TEY7    ), 
UBP33_MOUSE (Q8R5K2    ), UBP33_PONAB (Q5REG5    ), UBP33_XENTR (Q28CN3    ), 
UBP34_HUMAN (Q70CQ2    ), UBP34_MOUSE (Q6ZQ93    ), UBP35_HUMAN (Q9P2H5    ), 
UBP36_DROAN (B3M3M6    ), UBP36_DROER (B3NC86    ), UBP36_DROGR (B4IXE0    ), 
UBP36_DROME (Q9VRP5    ), UBP36_DROMO (B4KXJ5    ), UBP36_DROPS (Q2LZB1    ), 
UBP36_DROSE (B4HUI5    ), UBP36_DROSI (B4QIS3    ), UBP36_DROVI (B4LG38    ), 
UBP36_DROWI (B4MLR8    ), UBP36_DROYA (B4PIW8    ), UBP36_HUMAN (Q9P275    ), 
UBP36_MOUSE (B1AQJ2    ), UBP37_BOVIN (F1N5V1    ), UBP37_CANLF (E2RK09    ), 
UBP37_CHICK (E1C213    ), UBP37_DANRE (E7F6T8    ), UBP37_HUMAN (Q86T82    ), 
UBP37_MOUSE (Q8C0R0    ), UBP37_PIG   (F1SRY5    ), UBP38_HUMAN (Q8NB14    ), 
UBP38_MOUSE (Q8BW70    ), UBP3_ARATH  (O24454    ), UBP3_HUMAN  (Q9Y6I4    ), 
UBP3_MOUSE  (Q91W36    ), UBP3_SCHPO  (O94269    ), UBP3_YEAST  (Q01477    ), 
UBP40_HUMAN (Q9NVE5    ), UBP40_MOUSE (Q8BWR4    ), UBP41_HUMAN (Q3LFD5    ), 
UBP42_BOVIN (E1B9W9    ), UBP42_HUMAN (Q9H9J4    ), UBP42_MOUSE (B2RQC2    ), 
UBP42_RAT   (D3ZU96    ), UBP43_HUMAN (Q70EL4    ), UBP43_MOUSE (Q8BUM9    ), 
UBP44_AILME (D2HBJ8    ), UBP44_DANRE (Q7ZUM8    ), UBP44_HUMAN (Q9H0E7    ), 
UBP44_MOUSE (Q8C2S0    ), UBP44_XENTR (Q0V9G5    ), UBP45_HUMAN (Q70EL2    ), 
UBP45_MOUSE (Q8K387    ), UBP46_CAEEL (P34547    ), UBP46_DANRE (A5WWB0    ), 
UBP46_HUMAN (P62068    ), UBP46_MOUSE (P62069    ), UBP46_PONAB (Q5RBQ4    ), 
UBP46_RAT   (F1M625    ), UBP47_CHICK (E1C1R4    ), UBP47_HUMAN (Q96K76    ), 
UBP47_MOUSE (Q8BY87    ), UBP47_XENLA (Q5U252    ), UBP47_XENTR (A1A5G2    ), 
UBP48_CHICK (Q5ZM45    ), UBP48_HUMAN (Q86UV5    ), UBP48_MOUSE (Q3V0C5    ), 
UBP48_RAT   (Q76LT8    ), UBP49_HUMAN (Q70CQ1    ), UBP49_MOUSE (Q6P9L4    ), 
UBP4_ARATH  (Q8LAM0    ), UBP4_ASHGO  (Q754R5    ), UBP4_BOVIN  (A6QR55    ), 
UBP4_HUMAN  (Q13107    ), UBP4_KLULA  (Q9HFS7    ), UBP4_MOUSE  (P35123    ), 
UBP4_PONAB  (Q5RCD3    ), UBP4_RAT    (B2GUZ1    ), UBP4_SCHPO  (O60139    ), 
UBP4_VANPO  (A7TGY3    ), UBP4_YEAS1  (B3LGK1    ), UBP4_YEAS7  (A6ZY34    ), 
UBP4_YEAST  (P32571    ), UBP50_HUMAN (Q70EL3    ), UBP50_MACFA (Q4R6D3    ), 
UBP50_MOUSE (Q6P8X6    ), UBP51_HUMAN (Q70EK9    ), UBP5_ARATH  (O22207    ), 
UBP5_HUMAN  (P45974    ), UBP5_MOUSE  (P56399    ), UBP5_PONAB  (Q5R407    ), 
UBP5_SCHPO  (Q09879    ), UBP5_YEAST  (P39944    ), UBP6_ARATH  (Q949Y0    ), 
UBP6_HUMAN  (P35125    ), UBP6_SCHPO  (Q92353    ), UBP6_YEAST  (P43593    ), 
UBP7_ARATH  (Q84WC6    ), UBP7_CAEBR  (Q60MK8    ), UBP7_CAEEL  (Q7JKC3    ), 
UBP7_CHICK  (Q6U7I1    ), UBP7_DROME  (Q9VYQ8    ), UBP7_HUMAN  (Q93009    ), 
UBP7_MOUSE  (Q6A4J8    ), UBP7_RAT    (Q4VSI4    ), UBP7_SCHPO  (Q9P7S5    ), 
UBP7_YEAST  (P40453    ), UBP8_ARATH  (Q9C585    ), UBP8_HUMAN  (P40818    ), 
UBP8_MOUSE  (Q80U87    ), UBP8_SCHPO  (Q09738    ), UBP8_YEAST  (P50102    ), 
UBP9_ARATH  (Q93Y01    ), UBP9_SCHPO  (Q9P7V9    ), UBP9_YEAST  (P39967    ), 
UBPA_DICDI  (P54201    ), UBPB_DICDI  (O96612    ), UBPE_DROME  (Q24574    ), 
UBPL1_MIMIV (Q5UQR3    ), UBPY_CAEEL  (Q09931    ), UL17C_HUMAN (C9JPN9    ), 
UP44A_XENLA (Q6NTR6    ), UP44B_XENLA (Q5XGZ2    ), USP9X_HUMAN (Q93008    ), 
USP9X_MOUSE (P70398    ), USP9Y_HUMAN (O00507    )
» more

UniProtKB/Swiss-Prot
False negative sequences
25 sequences

CYLD_BOVIN  (Q1RMU2    ), CYLD_HUMAN  (Q9NQC7    ), CYLD_MOUSE  (Q80TQ2    ), 
CYLD_PONAB  (Q5RED8    ), CYLD_RAT    (Q66H62    ), SNUT2_HUMAN (Q53GS9    ), 
SNUT2_MOUSE (Q3TIX9    ), SNUT2_PONAB (Q5R761    ), U17L4_HUMAN (A6NCW7    ), 
U17L8_HUMAN (P0C7I0    ), UBP10_SCHPO (Q9USR2    ), UBP15_ARATH (Q9FPS9    ), 
UBP16_ARATH (Q9SB51    ), UBP17_ARATH (Q9FKP5    ), UBP18_ARATH (Q67XW5    ), 
UBP19_ARATH (Q9SJA1    ), UBP22_ARATH (Q9LEW0    ), UBP27_ARATH (Q9FPS0    ), 
UBP54_HUMAN (Q70EL1    ), UBP54_MOUSE (Q8BL06    ), UBP54_RAT   (Q6IE24    ), 
UBPL2_MIMIV (Q5UPW7    ), USPL1_DANRE (Q6DRC5    ), USPL1_HUMAN (Q5W0Q7    ), 
USPL1_MOUSE (Q3ULM6    )
» more

PDB
[Detailed view]
44 PDB

1NB8; 1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2GFO; 2HD5; 2IBI; 2Y5B; 2Y6E; 3I3T; 3IHP; 3M99; 3MHH; 3MHS; 3MTN; 3N3K; 3NHE; 3V6C; 3V6E; 4FIP; 4FJC; 4FK5; 4M5W; 4M5X; 4WA6; 4ZUX; 5A5B; 5CHT; 5CHV; 5CVM; 5CVN; 5CVO; 5FWI; 5GJQ; 5J7T; 5JTJ; 5K16; 5K1A; 5K1B; 5K1C; 5L8H; 5L8W
» more

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