Entry: PS00973

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General information about the entry

Entry name [info] USP_2
Accession [info] PS00973
Entry type [info] PATTERN
Date [info] JUN-1994 (CREATED); DEC-2013 (DATA UPDATE); FEB-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU10093

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain signature 2.
Pattern [info]
[YMF]-x-[LK]-x-[SAGNC]-[LIVMFT]-x(2)-H-x-G-x(4,6)-G-H-[YF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_03 which contains 542'782 sequence entries.


Total number of hits 281 in 281 different sequences
Number of true positive hits 281 in 281 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 25
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.83 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 13
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
281 sequences

CREB_ASPCL  (A1CIL1), CREB_ASPFC  (B0Y4P5), CREB_ASPFN  (B8NSV5), 
CREB_ASPFU  (Q4WQI1), CREB_ASPNC  (A2Q9N1), CREB_ASPOR  (Q2UUG8), 
CREB_ASPTN  (Q0CT11), CREB_EMENI  (Q96V54), CREB_NEOFI  (A1CW53), 
FAF_DROME   (P55824), NOT_DROME   (Q9VVR1), U17L1_HUMAN (Q7RTZ2), 
U17L2_HUMAN (Q6R6M4), U17L3_HUMAN (A6NCW0), U17L5_HUMAN (A8MUK1), 
U17L6_HUMAN (Q6QN14), U17L7_HUMAN (P0C7H9), U17LA_HUMAN (C9JJH3), 
U17LB_HUMAN (C9JVI0), U17LD_HUMAN (C9JLJ4), U17LF_HUMAN (C9J2P7), 
U17LH_HUMAN (D6RBQ6), U17LI_HUMAN (D6R9N7), U17LJ_HUMAN (D6RCP7), 
U17LK_HUMAN (D6RJB6), U17LL_HUMAN (D6R901), U17LM_HUMAN (D6RA61), 
U17LO_HUMAN (Q0WX57), U17PA_MOUSE (Q61068), U17PE_MOUSE (Q7M764), 
UB10A_XENLA (Q2NL57), UB10B_XENLA (Q7ZXR7), UB12A_XENLA (Q52KZ6), 
UB12B_XENLA (Q5M981), UB22A_XENLA (Q6GNI6), UB22B_XENLA (Q6DCJ1), 
UBP10_ARATH (Q9ZSB5), UBP10_BOVIN (A5PJS6), UBP10_HUMAN (Q14694), 
UBP10_MOUSE (P52479), UBP10_RAT   (Q3KR59), UBP10_XENTR (Q6DIJ4), 
UBP10_YEAST (P53874), UBP11_ARATH (Q9MAQ3), UBP11_CANFA (Q01988), 
UBP11_HUMAN (P51784), UBP11_MOUSE (Q99K46), UBP11_SCHPO (Q9UUD6), 
UBP11_YEAST (P36026), UBP12_ARATH (Q9FPT1), UBP12_BOVIN (A5D9H7), 
UBP12_DANRE (A4FUN7), UBP12_HUMAN (O75317), UBP12_MOUSE (Q9D9M2), 
UBP12_SALSA (C0HB46), UBP12_SCHPO (O60079), UBP12_YEAST (P39538), 
UBP13_ARATH (Q84WU2), UBP13_BOVIN (E1BMF7), UBP13_CHICK (E1BY77), 
UBP13_DANRE (F1QFS9), UBP13_HUMAN (Q92995), UBP13_MOUSE (Q5BKP2), 
UBP13_XENTR (F6V6I0), UBP13_YEAST (P38187), UBP14_ARATH (Q8L6Y1), 
UBP14_BOVIN (Q0IIF7), UBP14_CAEEL (Q17361), UBP14_HUMAN (P54578), 
UBP14_MOUSE (Q9JMA1), UBP14_PANTR (P60051), UBP14_RABIT (P40826), 
UBP14_SCHPO (Q11119), UBP14_YEAST (P38237), UBP15_BOVIN (Q2HJE4), 
UBP15_HUMAN (Q9Y4E8), UBP15_MOUSE (Q8R5H1), UBP15_RAT   (Q9R085), 
UBP15_XENTR (F6Z5C0), UBP15_YEAST (P50101), UBP16_BOVIN (Q08DA3), 
UBP16_DANRE (A8HAL1), UBP16_EMENI (P0CAQ1), UBP16_HUMAN (Q9Y5T5), 
UBP16_MACFA (Q4R6X7), UBP16_MOUSE (Q99LG0), UBP16_RAT   (Q2KJ09), 
UBP16_SCHPO (O74442), UBP16_XENLA (Q6PAW2), UBP16_XENTR (Q0VA64), 
UBP16_YEAST (Q02863), UBP18_HUMAN (Q9UMW8), UBP18_MOUSE (Q9WTV6), 
UBP18_PONAB (Q5RE63), UBP19_HUMAN (O94966), UBP19_MOUSE (Q3UJD6), 
UBP19_RAT   (Q6J1Y9), UBP1_ARATH  (Q9FPT5), UBP1_BOVIN  (Q29RP1), 
UBP1_HUMAN  (O94782), UBP1_MOUSE  (Q8BJQ2), UBP1_RAT    (Q569C3), 
UBP1_SCHPO  (Q9USM5), UBP1_YEAST  (P25037), UBP20_ARATH (Q9FPS7), 
UBP20_BOVIN (A7Z056), UBP20_DANRE (A5PN09), UBP20_HUMAN (Q9Y2K6), 
UBP20_MOUSE (Q8C6M1), UBP20_PONAB (Q5R5Z6), UBP20_XENLA (B1WBD7), 
UBP20_XENTR (A0JM59), UBP21_ARATH (Q9FIQ1), UBP21_BOVIN (Q2KJ72), 
UBP21_HUMAN (Q9UK80), UBP21_MOUSE (Q9QZL6), UBP21_RAT   (B2GUX4), 
UBP21_SCHPO (Q9UTT1), UBP22_BOVIN (P0C8Z3), UBP22_DANRE (A6H8I0), 
UBP22_HUMAN (Q9UPT9), UBP22_MOUSE (Q5DU02), UBP23_ARATH (Q9FPS4), 
UBP24_ARATH (Q9FPS3), UBP24_HUMAN (Q9UPU5), UBP24_MOUSE (B1AY13), 
UBP25_ARATH (Q9FPS2), UBP25_HUMAN (Q9UHP3), UBP25_MOUSE (P57080), 
UBP26_ARATH (Q9SCJ9), UBP26_HUMAN (Q9BXU7), UBP26_MOUSE (Q99MX1), 
UBP26_ORYSI (A2XDG4), UBP26_ORYSJ (A3AF13), UBP27_HUMAN (A6NNY8), 
UBP27_MOUSE (Q8CEG8), UBP28_CHICK (Q5ZID5), UBP28_HUMAN (Q96RU2), 
UBP28_MOUSE (Q5I043), UBP28_RAT   (D3ZJ96), UBP29_HUMAN (Q9HBJ7), 
UBP29_MOUSE (Q9ES63), UBP2_ARATH  (Q8W4N3), UBP2_BOVIN  (Q2KHV7), 
UBP2_CHICK  (O57429), UBP2_HUMAN  (O75604), UBP2_KLULA  (O42726), 
UBP2_MOUSE  (O88623), UBP2_RAT    (Q5U349), UBP2_SCHPO  (Q9P3U0), 
UBP2_YEAST  (Q01476), UBP30_DANRE (A2BGT0), UBP30_HUMAN (Q70CQ3), 
UBP30_MOUSE (Q3UN04), UBP30_XENTR (A4QNN3), UBP31_HUMAN (Q70CQ4), 
UBP32_HUMAN (Q8NFA0), UBP33_BOVIN (A6QNM7), UBP33_DANRE (A5PMR2), 
UBP33_HUMAN (Q8TEY7), UBP33_MOUSE (Q8R5K2), UBP33_PONAB (Q5REG5), 
UBP33_XENTR (Q28CN3), UBP34_HUMAN (Q70CQ2), UBP34_MOUSE (Q6ZQ93), 
UBP35_HUMAN (Q9P2H5), UBP36_DROAN (B3M3M6), UBP36_DROER (B3NC86), 
UBP36_DROGR (B4IXE0), UBP36_DROME (Q9VRP5), UBP36_DROMO (B4KXJ5), 
UBP36_DROPS (Q2LZB1), UBP36_DROSE (B4HUI5), UBP36_DROSI (B4QIS3), 
UBP36_DROVI (B4LG38), UBP36_DROWI (B4MLR8), UBP36_DROYA (B4PIW8), 
UBP36_HUMAN (Q9P275), UBP36_MOUSE (B1AQJ2), UBP37_BOVIN (F1N5V1), 
UBP37_CANFA (E2RK09), UBP37_CHICK (E1C213), UBP37_DANRE (E7F6T8), 
UBP37_HUMAN (Q86T82), UBP37_MOUSE (Q8C0R0), UBP37_PIG   (F1SRY5), 
UBP38_HUMAN (Q8NB14), UBP38_MOUSE (Q8BW70), UBP3_ARATH  (O24454), 
UBP3_HUMAN  (Q9Y6I4), UBP3_MOUSE  (Q91W36), UBP3_SCHPO  (O94269), 
UBP3_YEAST  (Q01477), UBP40_HUMAN (Q9NVE5), UBP40_MOUSE (Q8BWR4), 
UBP41_HUMAN (Q3LFD5), UBP42_BOVIN (E1B9W9), UBP42_HUMAN (Q9H9J4), 
UBP42_MOUSE (B2RQC2), UBP42_RAT   (D3ZU96), UBP43_HUMAN (Q70EL4), 
UBP43_MOUSE (Q8BUM9), UBP44_AILME (D2HBJ8), UBP44_DANRE (Q7ZUM8), 
UBP44_HUMAN (Q9H0E7), UBP44_MOUSE (Q8C2S0), UBP44_XENTR (Q0V9G5), 
UBP45_HUMAN (Q70EL2), UBP45_MOUSE (Q8K387), UBP46_DANRE (A5WWB0), 
UBP46_HUMAN (P62068), UBP46_MOUSE (P62069), UBP46_PONAB (Q5RBQ4), 
UBP47_CHICK (E1C1R4), UBP47_HUMAN (Q96K76), UBP47_MOUSE (Q8BY87), 
UBP47_XENLA (Q5U252), UBP47_XENTR (A1A5G2), UBP48_CHICK (Q5ZM45), 
UBP48_HUMAN (Q86UV5), UBP48_MOUSE (Q3V0C5), UBP48_RAT   (Q76LT8), 
UBP49_HUMAN (Q70CQ1), UBP49_MOUSE (Q6P9L4), UBP4_ARATH  (Q8LAM0), 
UBP4_ASHGO  (Q754R5), UBP4_BOVIN  (A6QR55), UBP4_HUMAN  (Q13107), 
UBP4_KLULA  (Q9HFS7), UBP4_MOUSE  (P35123), UBP4_PONAB  (Q5RCD3), 
UBP4_RAT    (B2GUZ1), UBP4_SCHPO  (O60139), UBP4_VANPO  (A7TGY3), 
UBP4_YEAS1  (B3LGK1), UBP4_YEAS7  (A6ZY34), UBP4_YEAST  (P32571), 
UBP50_HUMAN (Q70EL3), UBP50_MACFA (Q4R6D3), UBP50_MOUSE (Q6P8X6), 
UBP51_HUMAN (Q70EK9), UBP5_ARATH  (O22207), UBP5_HUMAN  (P45974), 
UBP5_MOUSE  (P56399), UBP5_PONAB  (Q5R407), UBP5_SCHPO  (Q09879), 
UBP5_YEAST  (P39944), UBP6_ARATH  (Q949Y0), UBP6_HUMAN  (P35125), 
UBP6_SCHPO  (Q92353), UBP6_YEAST  (P43593), UBP7_ARATH  (Q84WC6), 
UBP7_CAEBR  (Q60MK8), UBP7_CAEEL  (Q7JKC3), UBP7_CHICK  (Q6U7I1), 
UBP7_DROME  (Q9VYQ8), UBP7_HUMAN  (Q93009), UBP7_MOUSE  (Q6A4J8), 
UBP7_RAT    (Q4VSI4), UBP7_SCHPO  (Q9P7S5), UBP7_YEAST  (P40453), 
UBP8_ARATH  (Q9C585), UBP8_HUMAN  (P40818), UBP8_MOUSE  (Q80U87), 
UBP8_SCHPO  (Q09738), UBP8_YEAST  (P50102), UBP9_ARATH  (Q93Y01), 
UBP9_SCHPO  (Q9P7V9), UBP9_YEAST  (P39967), UBPA_DICDI  (P54201), 
UBPB_DICDI  (O96612), UBPE_DROME  (Q24574), UBPL1_MIMIV (Q5UQR3), 
UBPX_CAEEL  (P34547), UBPY_CAEEL  (Q09931), UL17C_HUMAN (C9JPN9), 
UP44A_XENLA (Q6NTR6), UP44B_XENLA (Q5XGZ2), USP9X_HUMAN (Q93008), 
USP9X_MOUSE (P70398), USP9Y_HUMAN (O00507)
» More

UniProtKB/Swiss-Prot
False negative sequences
25 sequences

CYLD_BOVIN  (Q1RMU2), CYLD_HUMAN  (Q9NQC7), CYLD_MOUSE  (Q80TQ2), 
CYLD_PONAB  (Q5RED8), CYLD_RAT    (Q66H62), SNUT2_HUMAN (Q53GS9), 
SNUT2_MOUSE (Q3TIX9), SNUT2_PONAB (Q5R761), U17L4_HUMAN (A6NCW7), 
U17L8_HUMAN (P0C7I0), UBP10_SCHPO (Q9USR2), UBP15_ARATH (Q9FPS9), 
UBP16_ARATH (Q9SB51), UBP17_ARATH (Q9FKP5), UBP18_ARATH (Q67XW5), 
UBP19_ARATH (Q9SJA1), UBP22_ARATH (Q9LEW0), UBP27_ARATH (Q9FPS0), 
UBP54_HUMAN (Q70EL1), UBP54_MOUSE (Q8BL06), UBP54_RAT   (Q6IE24), 
UBPL2_MIMIV (Q5UPW7), USPL1_DANRE (Q6DRC5), USPL1_HUMAN (Q5W0Q7), 
USPL1_MOUSE (Q3ULM6)
» More

PDB
[Detailed view]
24 PDB

1NB8; 1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2GFO; 2HD5; 2IBI; 2Y5B; 2Y6E; 3I3T; 3IHP; 3M99; 3MHH; 3MHS; 3MTN; 3N3K; 3NHE; 3V6C; 3V6E; 4FIP; 4FJC; 4FK5
» More

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