Entry: PS01121

General information about the entry

Entry name [info] CASPASE_HIS
Accession [info] PS01121
Entry type [info] PATTERN
Date [info] NOV-1995 (CREATED); DEC-2004 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00864

Name and characterization of the entry

Description [info] Caspase family histidine active site.
Pattern [info]
H-x(2,4)-[SC]-x(2)-{A}-x-[LIVMF](2)-[ST]-H-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 61 in 61 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 86.89 %
Recall (true positives / (true positives + false negatives)) 92.98 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

CAS1A_XENLA (P55865), CAS1B_XENLA (P55867), CASP1_CANFA (Q9MZV7), 
CASP1_DROME (O02002), CASP1_FELCA (Q9MZV6), CASP1_HORSE (Q9TV13), 
CASP1_HUMAN (P29466), CASP1_MOUSE (P29452), CASP1_PIG   (Q9N2I1), 
CASP1_RAT   (P43527), CASP1_SPOFR (P89116), CASP2_CHICK (Q98943), 
CASP2_HUMAN (P42575), CASP2_MOUSE (P29594), CASP2_RAT   (P55215), 
CASP3_BOVIN (Q08DY9), CASP3_CANFA (Q8MKI5), CASP3_FELCA (Q8MJU1), 
CASP3_HUMAN (P42574), CASP3_MACFA (Q2PFV2), CASP3_MESAU (Q60431), 
CASP3_MOUSE (P70677), CASP3_PANTR (Q5IS54), CASP3_PIG   (Q95ND5), 
CASP3_RABIT (Q8MJC3), CASP3_RAT   (P55213), CASP3_SAIBB (Q5IS99), 
CASP3_XENLA (P55866), CASP4_BOVIN (Q5E9C1), CASP4_HUMAN (P49662), 
CASP4_MOUSE (P70343), CASP5_HUMAN (P51878), CASP6_BOVIN (Q3T0P5), 
CASP6_HUMAN (P55212), CASP6_MOUSE (O08738), CASP6_RAT   (O35397), 
CASP7_HUMAN (P55210), CASP7_MESAU (P55214), CASP7_MOUSE (P97864), 
CASP8_HUMAN (Q14790), CASP8_MOUSE (O89110), CASP8_RAT   (Q9JHX4), 
CASP9_HUMAN (P55211), CASP9_MOUSE (Q8C3Q9), CASPA_HUMAN (Q92851), 
CASPC_CANFA (Q075B4), CASPC_MACMU (Q153Z0), CASPC_MOUSE (O08736), 
CASPC_RAT   (Q920D5), CASPD_BOVIN (O75601), CED3_CAEEL  (P42573), 
CED3_CAERE  (P45436), DRICE_DROME (O01382)
» More

UniProtKB/Swiss-Prot
False negative sequences
4 sequences

CASP8_DROME (Q8IRY7), CASPE_HUMAN (P31944), CASPE_MOUSE (O89094), 
ICENC_DROME (Q9XYF4)
» More

UniProtKB/Swiss-Prot
False positive sequences
8 sequences

ACCC_ALLVD  (O52058), CESAA_ARATH (Q9SKJ5), FENR_STAS1  (Q49ZU9), 
PARP2_HUMAN (Q9UGN5), PARP2_MOUSE (O88554), RN133_MACFA (Q95K04), 
RPOD_BUCAP  (P32001), TDRD5_DANRE (Q1L981)
» More

PDB
[Detailed view]
197 PDB

1BMQ; 1CP3; 1F1J; 1F9E; 1GFW; 1GQF; 1I3O; 1I4E; 1I4O; 1I51; 1IBC; 1ICE; 1JXQ; 1K86; 1K88; 1KMC; 1M72; 1NME; 1NMQ; 1NMS; 1NW9; 1PAU; 1PYO; 1QDU; 1QTN; 1QX3; 1RE1; 1RHJ; 1RHK; 1RHM; 1RHQ; 1RHR; 1RHU; 1RWK; 1RWM; 1RWN; 1RWO; 1RWP; 1RWV; 1RWW; 1RWX; 1SC1; 1SC3; 1SC4; 1SHJ; 1SHL; 2AR9; 2C1E; 2C2K; 2C2M; 2C2O; 2C2Z; 2CDR; 2CJX; 2CJY; 2CNK; 2CNL; 2CNN; 2CNO; 2DKO; 2FQQ; 2FUN; 2H48; 2H4W; 2H4Y; 2H51; 2H54; 2H5I; 2H5J; 2H65; 2HBQ; 2HBR; 2HBY; 2HBZ; 2J30; 2J31; 2J32; 2J33; 2K7Z; 2P2C; 2QL5; 2QL7; 2QL9; 2QLB; 2QLF; 2QLJ; 2WDP; 2XYG; 2XYH; 2XYP; 2XZD; 2XZT; 2Y0B; 2Y1L; 3D6F; 3D6H; 3D6M; 3DEH; 3DEI; 3DEJ; 3DEK; 3E4C; 3EDQ; 3EDR; 3GJQ; 3GJR; 3GJS; 3GJT; 3H0E; 3H11; 3H1P; 3IBC; 3IBF; 3ITN; 3K7E; 3KJF; 3KJN; 3KJQ; 3NKF; 3NR2; 3NS7; 3OD5; 3P45; 3P4U; 3PCX; 3PD0; 3PD1; 3QNW; 3R5J; 3R5K; 3R6G; 3R6L; 3R7B; 3R7N; 3R7S; 3RJM; 3S70; 3S8E; 3SIP; 3SIR; 3V3K; 3V6L; 3V6M; 4DCJ; 4DCO; 4DCP; 4EHA; 4EHD; 4EHF; 4EHH; 4EHK; 4EHL; 4EHN; 4EJF; 4FDL; 4FEA; 4FXO; 4HQ0; 4HQR; 4HVA; 4JB8; 4JJ7; 4JJ8; 4JJE; 4JQY; 4JQZ; 4JR0; 4JR1; 4JR2; 4LSZ; 4M9R; 4N5D; 4N6G; 4N7J; 4N7M; 4NBK; 4NBL; 4NBN; 4PRY; 4PRZ; 4PS0; 4PS1; 4QTX; 4QTY; 4QU0; 4QU5; 4QU8; 4QU9; 4QUA; 4QUB; 4QUD; 4QUE; 4QUG; 4QUH; 4QUI; 4QUJ; 4QUL
» More

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