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PROSITE entry PS01122


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General information about the entry

Entry name [info] CASPASE_CYS
Accession [info] PS01122
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00864

Name and characterization of the entry

Description [info] Caspase family cysteine active site.
Pattern [info]
K-P-K-[LIVMF]-[LIVMFY]-[LIVMF](2)-[QP]-[AF]-C-[RQG]-[GE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 62 in 62 different sequences
Number of true positive hits 62 in 62 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
62 sequences

CAS1A_XENLA (P55865), CAS1B_XENLA (P55867), CASP1_CANLF (Q9MZV7), 
CASP1_DROME (O02002), CASP1_FELCA (Q9MZV6), CASP1_HORSE (Q9TV13), 
CASP1_HUMAN (P29466), CASP1_MOUSE (P29452), CASP1_PIG   (Q9N2I1), 
CASP1_RAT   (P43527), CASP1_SPOFR (P89116), CASP2_CHICK (Q98943), 
CASP2_HUMAN (P42575), CASP2_MOUSE (P29594), CASP2_RAT   (P55215), 
CASP3_BOVIN (Q08DY9), CASP3_CANLF (Q8MKI5), CASP3_FELCA (Q8MJU1), 
CASP3_HUMAN (P42574), CASP3_MACFA (Q2PFV2), CASP3_MESAU (Q60431), 
CASP3_MOUSE (P70677), CASP3_PANTR (Q5IS54), CASP3_PIG   (Q95ND5), 
CASP3_RABIT (Q8MJC3), CASP3_RAT   (P55213), CASP3_SAIBB (Q5IS99), 
CASP3_XENLA (P55866), CASP4_BOVIN (Q5E9C1), CASP4_HUMAN (P49662), 
CASP4_MOUSE (P70343), CASP5_HUMAN (P51878), CASP6_BOVIN (Q3T0P5), 
CASP6_CHICK (A0A1D5PPP7), CASP6_HUMAN (P55212), CASP6_MOUSE (O08738), 
CASP6_RAT   (O35397), CASP7_CHICK (F1NV61), CASP7_HUMAN (P55210), 
CASP7_MESAU (P55214), CASP7_MOUSE (P97864), CASP8_DROME (Q8IRY7), 
CASP8_HUMAN (Q14790), CASP8_MOUSE (O89110), CASP8_RAT   (Q9JHX4), 
CASP9_HUMAN (P55211), CASP9_MOUSE (Q8C3Q9), CASPA_DANRE (Q9I9L7), 
CASPA_HUMAN (Q92851), CASPB_DANRE (Q504J1), CASPC_CANLF (Q075B4), 
CASPC_HUMAN (Q6UXS9), CASPC_MACMU (Q153Z0), CASPC_MOUSE (O08736), 
CASPC_RAT   (Q920D5), CASPD_BOVIN (O75601), CASPE_HUMAN (P31944), 
CASPE_MOUSE (O89094), CED3_CAEEL  (P42573), CED3_CAERE  (P45436), 
DRICE_DROME (O01382), DRONC_DROME (Q9XYF4)
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PDB
[Detailed view]
216 PDB

1BMQ; 1CP3; 1F1J; 1F9E; 1GFW; 1I4E; 1I4O; 1I51; 1IBC; 1ICE; 1JXQ; 1K86; 1M72; 1NME; 1NMQ; 1NMS; 1NW9; 1PAU; 1PYO; 1QDU; 1QTN; 1QX3; 1RE1; 1RHJ; 1RHK; 1RHM; 1RHQ; 1RHR; 1RHU; 1RWK; 1RWM; 1RWN; 1RWO; 1RWP; 1RWV; 1RWW; 1RWX; 1SHJ; 1SHL; 2C1E; 2C2K; 2C2M; 2C2O; 2C2Z; 2CDR; 2CJX; 2CJY; 2CNK; 2CNL; 2CNN; 2CNO; 2DKO; 2FUN; 2H48; 2H4W; 2H54; 2H5I; 2H5J; 2H65; 2HBQ; 2HBY; 2J30; 2J31; 2J32; 2J33; 2NN3; 2P2C; 2QL5; 2QL7; 2QL9; 2QLB; 2QLF; 2QLJ; 2WDP; 2XYG; 2XYH; 2XYP; 2XZD; 2XZT; 2Y0B; 2Y1L; 3D6F; 3D6H; 3D6M; 3DEH; 3DEI; 3DEJ; 3DEK; 3EDQ; 3EDR; 3GJQ; 3GJR; 3GJS; 3GJT; 3H0E; 3H11; 3H1P; 3IBC; 3IBF; 3ITN; 3J9K; 3K7E; 3KJF; 3KJN; 3KJQ; 3NKF; 3NS7; 3OD5; 3P45; 3P4U; 3PCX; 3PD0; 3PD1; 3QNW; 3R5J; 3R5K; 3R6G; 3R6L; 3R7B; 3R7N; 3R7S; 3RJM; 3S70; 3S8E; 3SIP; 3SIR; 3V3K; 3V6L; 3V6M; 4DCJ; 4DCO; 4DCP; 4EHA; 4EHD; 4EHF; 4EHH; 4EHK; 4EHL; 4EHN; 4FDL; 4FEA; 4FXO; 4HQ0; 4HQR; 4HVA; 4IYR; 4JB8; 4JJ7; 4JJ8; 4JJE; 4JR0; 4JR1; 4JR2; 4LSZ; 4PRY; 4PRZ; 4PS0; 4PS1; 4QTX; 4QTY; 4QU0; 4QU5; 4QU8; 4QU9; 4QUA; 4QUB; 4QUD; 4QUE; 4QUG; 4QUH; 4QUI; 4QUJ; 4QUL; 4ZVO; 4ZVP; 4ZVQ; 4ZVR; 4ZVS; 4ZVT; 4ZVU; 5I9B; 5I9T; 5IAB; 5IAE; 5IAG; 5IAJ; 5IAK; 5IAN; 5IAR; 5IAS; 5IBC; 5IBP; 5IBR; 5IC4; 5IC6; 5K20; 5MMV; 5MTK; 5V6U; 5V6Z; 6BZ9; 6DEU; 6DEV; 6F6R; 6PX9; 6PZP; 7XN4; 7XN5; 7XN6; 8DGZ; 8DJ3; 8EG5; 8EG6; 8JOL; 8SV1; 8WRA
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