Entry: PS01351

General information about the entry
Entry name MAPK
Accession number PS01351
Entry type PATTERN
Date DEC-2001 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC01049
Name and characterization of the entry
DescriptionMAP kinase signature.
Pattern F-x(10)-R-E-x(72,86)-R-D-x-K-x(9)-[CS].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 183 hits in 183 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 182 hits in 182 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 1 hits in 1 different sequences
  • Number of known missed hits: 4
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 99.45 %
  • Recall (true hits / (true hits + false negatives)): 97.85 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CPK1_CRYNB  (P0CP67), CPK1_CRYNJ  (P0CP66), ERK1_CANAL  (Q5A1D3), 
ERK1_CANAW  (C4YGK0), ERK1_DICDI  (P42525), ERK2_DICDI  (Q54QB1), 
ERKA_DROME  (P40417), FUS3_YEAST  (P16892), HOG1_ALTBR  (Q52PH6), 
HOG1_ASHGO  (Q750A9), HOG1_ASPCL  (A1CPG7), HOG1_ASPFU  (Q4WSF6), 
HOG1_ASPNC  (A2QRF6), HOG1_ASPTN  (Q0D0P5), HOG1_BEABA  (Q6PWX2), 
HOG1_BLAAD  (Q702W0), HOG1_BLUGR  (Q8TGA9), HOG1_BOTFB  (A1IVT7), 
HOG1_CANAL  (Q92207), HOG1_CANGA  (Q6FIU2), HOG1_CHAGB  (Q2H332), 
HOG1_COCHE  (Q4W6D3), HOG1_COCIM  (Q1DUU8), HOG1_COCMI  (Q2WFL5), 
HOG1_COLOR  (Q75Q66), HOG1_CRYNB  (P0CP69), HOG1_CRYNH  (Q56R42), 
HOG1_CRYNJ  (P0CP68), HOG1_CRYPA  (Q875L0), HOG1_DEBHA  (Q9UV50), 
HOG1_EMENI  (Q9P419), HOG1_EURHE  (Q38HL5), HOG1_FUSCU  (Q4PNJ1), 
HOG1_GIBIN  (Q4PKS0), HOG1_GIBZE  (P0C431), HOG1_HORWE  (Q8NJT7), 
HOG1_HYPAT  (Q6XKY3), HOG1_KLULA  (Q6CJA8), HOG1_MAGO7  (Q9UV51), 
HOG1_MYCGM  (Q1KTF2), HOG1_NEOFI  (A1D2C9), HOG1_NEUCR  (Q96TL5), 
HOG1_PHANO  (Q0U4L8), HOG1_PICST  (A3LN91), HOG1_SCHPO  (Q09892), 
HOG1_SETTU  (Q5I6M2), HOG1_TORDE  (Q1L5Z8), HOG1_TRIHA  (Q2WGK3), 
HOG1_USTMA  (Q4PC06), HOG1_YARLI  (Q6C4M9), HOG1_YEAST  (P32485), 
HOG1_ZYGRC  (O93982), HOG1_ZYGRO  (O59854), HOG2_ZYGRO  (O59853), 
JNK1_ANCCA  (Q9U6D2), JNK1_CAEEL  (Q8WQG9), JNK_DROME   (P92208), 
JNK_SUBDO   (Q966Y3), KSS1_YEAST  (P14681), MAPK1_PNECA (O94737), 
MAPK2_PNECA (O42781), MAPK_FUSSO  (Q00859), MAPK_PEA    (Q06060), 
MAPK_PETHY  (Q40884), MK01_BOVIN  (P46196), MK01_HUMAN  (P28482), 
MK01_MOUSE  (P63085), MK01_RAT    (P63086), MK01_XENLA  (P26696), 
MK03_HUMAN  (P27361), MK03_MOUSE  (Q63844), MK03_RAT    (P21708), 
MK07_BOVIN  (A5PKJ4), MK07_HUMAN  (Q13164), MK07_MOUSE  (Q9WVS8), 
MK07_RAT    (P0C865), MK08A_CYPCA (Q90327), MK08B_CYPCA (O42099), 
MK08_DANRE  (Q9DGD9), MK08_HUMAN  (P45983), MK08_MOUSE  (Q91Y86), 
MK08_RAT    (P49185), MK08_XENLA  (Q8QHK8), MK09_CHICK  (P79996), 
MK09_HUMAN  (P45984), MK09_MOUSE  (Q9WTU6), MK09_RAT    (P49186), 
MK10_HUMAN  (P53779), MK10_MOUSE  (Q61831), MK10_RAT    (P49187), 
MK11_HUMAN  (Q15759), MK11_MOUSE  (Q9WUI1), MK12_DANRE  (O42376), 
MK12_HUMAN  (P53778), MK12_MOUSE  (O08911), MK12_RAT    (Q63538), 
MK13_BOVIN  (Q3T0N5), MK13_HUMAN  (O15264), MK13_MOUSE  (Q9Z1B7), 
MK13_PANTR  (Q9N272), MK13_RAT    (Q9WTY9), MK14A_CYPCA (Q90336), 
MK14A_DANRE (Q9DGE2), MK14A_DROME (O62618), MK14B_CYPCA (Q9I958), 
MK14B_DANRE (Q9DGE1), MK14B_DROME (O61443), MK14C_DROME (P83100), 
MK14_CANFA  (O02812), MK14_HUMAN  (Q16539), MK14_MOUSE  (P47811), 
MK14_PANTR  (Q95NE7), MK14_RAT    (P70618), MK14_XENLA  (P47812), 
MK15_HUMAN  (Q8TD08), MK15_MOUSE  (Q80Y86), MK15_RAT    (Q9Z2A6), 
MKC1_CANAX  (P43068), MMK1_MEDSA  (Q07176), MMK2_MEDSA  (Q40353), 
MPK10_ARATH (Q9M1Z5), MPK10_ORYSJ (Q5ZCI1), MPK11_ARATH (Q9LMM5), 
MPK11_ORYSJ (Q5VN19), MPK12_ORYSJ (Q5Z9J0), MPK13_ARATH (Q9LQQ9), 
MPK13_ORYSI (A2X0M1), MPK13_ORYSJ (Q0E459), MPK14_ARATH (O23236), 
MPK14_ORYSJ (Q75KK8), MPK15_ARATH (Q9C9U4), MPK15_ORYSJ (Q53N72), 
MPK16_ARATH (Q8W4J2), MPK16_ORYSJ (Q5VP69), MPK17_ARATH (Q84M93), 
MPK17_ORYSJ (Q6L5F7), MPK18_ARATH (Q9C5C0), MPK19_ARATH (Q9LUC3), 
MPK1_ORYSJ  (Q84UI5), MPK20_ARATH (Q9SJG9), MPK2_ARATH  (Q39022), 
MPK3_ARATH  (Q39023), MPK3_ORYSJ  (Q6Z437), MPK4_ARATH  (Q39024), 
MPK4_ORYSJ  (Q5Z859), MPK5_ARATH  (Q39025), MPK5_ORYSI  (A2XFC8), 
MPK5_ORYSJ  (Q10N20), MPK6_ARATH  (Q39026), MPK6_ORYSJ  (Q336X9), 
MPK7_ARATH  (Q39027), MPK7_ORYSJ  (Q67C40), MPK8_ARATH  (Q9LM33), 
MPK8_ORYSJ  (Q5SN53), MPK9_ARATH  (Q9LV37), MPK9_ORYSJ  (Q6L5D4), 
MPKC_ASPCL  (A1CAF0), MPKC_ASPFU  (Q4WUN7), MPKC_ASPNC  (A2QN07), 
MPKC_ASPOR  (Q2U469), MPKC_ASPTN  (Q0CIC7), MPKC_EMENI  (Q9HG11), 
MPKC_NEOFI  (A1DES4), NLK2_XENLA  (Q8QGV6), NLK2_XENTR  (B1H3E1), 
NLK_BOVIN   (E1BMN8), NLK_CAEEL   (Q9U9Y8), NLK_CANFA   (E2QWQ2), 
NLK_HUMAN   (Q9UBE8), NLK_MOUSE   (O54949), NLK_RAT     (D3ZSZ3), 
NTF3_TOBAC  (Q40517), NTF4_TOBAC  (Q40532), NTF6_TOBAC  (Q40531), 
PMK1_CAEEL  (Q17446), PMK2_CAEEL  (Q8MXI4), PMK3_CAEEL  (O44514), 
SLT2_YEAST  (Q00772), SPK1_SCHPO  (P27638), SPM1_SCHPO  (Q92398), 
SUR1_CAEEL  (P39745), YPC2_CAEEL  (Q11179)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
MPK12_ARATH (Q8GYQ5), MPK1_ARATH  (Q39021), MPK2_ORYSJ  (Q5J4W4), 
SMK1_YEAST  (P41808)
False positive hits (sequences which do not belong to the set under consideration):
MRH4_MAGO7  (A4QTC6)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1A9U; 1BL6; 1BL7; 1BMK; 1CM8; 1DI9; 1ERK; 1GOL; 1IAN; 1JNK; 1KV1; 1KV2; 1LEW; 1LEZ; 1M7Q; 1OUK; 1OUY; 1OVE; 1OZ1; 1P38; 1PMN; 1PMQ; 1PMU; 1PMV; 1R39; 1R3C; 1TVO; 1UKH; 1UKI; 1W7H; 1W82; 1W83; 1W84; 1WBN; 1WBO; 1WBS; 1WBT; 1WBV; 1WBW; 1WFC; 1WZY; 1YQJ; 1YW2; 1YWR; 1ZYJ; 1ZZ2; 1ZZL; 2B1P; 2B9F; 2B9H; 2B9I; 2B9J; 2BAJ; 2BAK; 2ERK; 2EWA; 2EXC; 2F49; 2F9G; 2FA2; 2FSL; 2FSM; 2FSO; 2FST; 2FYS; 2G01; 2GFS; 2GHL; 2GHM; 2GMX; 2GPH; 2GTM; 2GTN; 2H96; 2I0H; 2LGC; 2NO3; 2NPQ; 2O0U; 2O2U; 2OJG; 2OJI; 2OJJ; 2OK1; 2OKR; 2ONL; 2OZA; 2P33; 2PUU; 2QD9; 2RG5; 2RG6; 2WAJ; 2XRW; 2XS0; 2Y8O; 2Y9Q; 2YIS; 2YIW; 2YIX; 2Z7L; 2ZAZ; 2ZB0; 2ZB1; 2ZDT; 2ZDU; 2ZOQ; 3BV2; 3BV3; 3BX5; 3C5U; 3C9W; 3CGF; 3CGO; 3COI; 3CTQ; 3D7Z; 3DA6; 3DS6; 3DT1; 3E7O; 3ELJ; 3ERK; 3FC1; 3FI4; 3FKL; 3FKN; 3FKO; 3FL4; 3FLN; 3FLQ; 3FLS; 3FLW; 3FLY; 3FLZ; 3FMH; 3FMJ; 3FMK; 3FML; 3FMM; 3FMN; 3FSF; 3FSK; 3G90; 3G9L; 3G9N; 3GC7; 3GC8; 3GC9; 3GCP; 3GCQ; 3GCS; 3GCU; 3GCV; 3GFE; 3GI3; 3GP0; 3HA8; 3HEC; 3HEG; 3HL7; 3HLL; 3HP2; 3HP5; 3HRB; 3HUB; 3HUC; 3HV3; 3HV4; 3HV5; 3HV6; 3HV7; 3HVC; 3I5Z; 3I60; 3ITZ; 3IW5; 3IW6; 3IW7; 3IW8; 3K3I; 3K3J; 3KF7; 3KQ7; 3L8S; 3L8X; 3LFA; 3LFB; 3LFC; 3LFD; 3LFE; 3LFF; 3LHJ; 3MGY; 3MH0; 3MH1; 3MH2; 3MH3; 3MPA; 3MPT; 3MVL; 3MVM; 3MW1; 3NEW; 3NNU; 3NNV; 3NNW; 3NNX; 3NPC; 3NWW; 3O17; 3O2M; 3O71; 3O8P; 3O8T; 3O8U; 3OBG; 3OBJ; 3OC1; 3OCG; 3OD6; 3ODY; 3ODZ; 3OEF; 3OXI; 3OY1; 3P4K; 3P5K; 3P78; 3P79; 3P7A; 3P7B; 3P7C; 3PG3; 3PTG; 3PY3; 3PZE; 3QUD; 3QUE; 3QYI; 3R63; 3RIN; 3ROC; 3S3I; 3S4Q; 3TEI; 3TG1; 3TTI; 3TTJ; 3U8W; 3UVP; 3UVQ; 3UVR; 3V3V; 3V6R; 3V6S; 3VUD; 3VUG; 3W55; 3ZS5; 3ZSG; 3ZSH; 3ZSI; 3ZU7; 3ZUV; 3ZYA; 4A9Y; 4AA0; 4AA4; 4AAC; 4B99; 4DLI; 4DLJ; 4E5A; 4E5B; 4E6A; 4E6C; 4E8A; 4EH2; 4EH3; 4EH4; 4EH5; 4EH6; 4EH7; 4EH8; 4EH9; 4EHV; 4ERK; 4EWQ; 4EXU; 4EYJ; 4EYM; 4FMQ; 4FV6; 4H36; 4H39; 4H3B; 4H3P; 4H3Q; 4IC7; 4IC8;

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