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Entry: PS50066

General information about the entry

Entry name [info] MADS_BOX_2
Accession [info] PS50066
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED; 10-MAY-2017 DATA UPDATE; 20-DEC-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00302
Associated ProRule [info] PRU00251

Name and characterization of the entry

Description [info] MADS-box domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=61;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=56;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4192000; R2=0.0140178; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4116.6396484; R2=6.2460656; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=577; H_SCORE=7721; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=434; H_SCORE=6827; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='M'; M=-10,-18,-21,-26,-16, -5,-21, -2, 13, -4, 12, 45,-17,-20,  1, -2,-17, -9,  7,-21, -2, -8;
/M: SY='G'; M=  6, -9,-25,-10,-14,-26, 44,-19,-30,-16,-24,-17, -2,-17,-16,-18,  3, -9,-21,-22,-26,-15;
/M: SY='R'; M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='G'; M= -5,-11,-29,-11,-14,-26, 36,-16,-32, -4,-25,-15, -2,-20,-12,  3, -4,-16,-21,-21,-23,-14;
/M: SY='K'; M=-11, -1,-30, -1, 10,-30,-20, -9,-30, 47,-29,-10,  0,-11, 12, 32,-10,-10,-20,-20,-10, 10;
/M: SY='I'; M= -8,-27,-26,-35,-26, -2,-36,-27, 40,-25, 16, 16,-20,-21,-16,-25,-16, -7, 28,-22, -3,-25;
/M: SY='E'; M=-10,  4,-31, 10, 40,-33,-20,  1,-26, 12,-21,-13, -1,  1, 30,  4, -1,-10,-29,-26,-17, 35;
/M: SY='I'; M=-10,-29,-27,-37,-27,  2,-36,-25, 41,-28, 25, 24,-22,-22,-18,-26,-22,-10, 25,-20,  0,-26;
/M: SY='K'; M=-10,  0,-28,  1, 15,-29,-18, -7,-29, 36,-27,-12,  1,-10, 13, 27, -4, -8,-21,-23,-12, 13;
/M: SY='R'; M=-18,-12,-29,-12, -3, -8,-22, -1,-23, 19,-17, -7, -5,-13,  2, 40,-12,-10,-17,-15, -1, -4;
/M: SY='I'; M=-10,-30,-29,-39,-29,  1,-39,-29, 47,-30, 23, 20,-21,-21,-20,-29,-21,-10, 28,-20,  0,-29;
/M: SY='E'; M=-11, 12,-29, 21, 48,-29,-19, -2,-29,  9,-19,-19,  1, -3, 15,  0, -1, -8,-27,-30,-18, 31;
/M: SY='N'; M=-13, 43,-23, 33,  5,-25, -3,  7,-25,  0,-30,-23, 49,-17,  0, -3,  7, -3,-30,-40,-20,  3;
/M: SY='K'; M= -2,  1,-23,  2,  5,-25,-14, -9,-21, 13,-22,-12,  2, -8,  6,  8,  4,  1,-15,-27,-14,  5;
/M: SY='T'; M= -5, -5,-18,-12, -9,-12,-21,-14, -4, -7, -6, -4, -1,-15, -3, -1,  6, 21, -1,-27, -9, -7;
/M: SY='N'; M= -8, 21,-21, 10,  1,-21, -6,  6,-22,  7,-28,-17, 35,-17,  2, 11, 10,  1,-24,-35,-16,  1;
/M: SY='R'; M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='Q'; M=-11, -2,-28, -3, 13,-31,-21, 15,-18,  5,-17,  0, -1,-13, 45,  6, -1, -7,-25,-19, -2, 28;
/M: SY='V'; M= -1,-22,-11,-24,-26, -2,-27,-26, 23,-18,  5,  6,-20,-28,-26,-18, -6,  3, 40,-31,-11,-26;
/M: SY='T'; M=  0,  0,-10,-10,-10,-10,-20,-20,-10,-10,-10,-10,  0,-10,-10,-10, 20, 50,  0,-30,-10,-10;
/M: SY='F'; M=-20,-28,-22,-36,-28, 70,-30,-12,  0,-26,  8,  0,-20,-30,-34,-18,-20,-10, -2, 14, 40,-28;
/M: SY='S'; M=  6, -3,  5, -7, -7,-18, -8,-15,-16,-13,-23,-16,  4,-15, -6,-14, 26, 17, -7,-38,-19, -7;
/M: SY='K'; M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='R'; M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='R'; M=-17, -7,-30, -7,  3,-23,-20, -3,-30, 36,-23,-10,  0,-17, 10, 57,-10,-10,-20,-20,-10,  3;
/M: SY='N'; M=  2, 13,-17,  1, -4,-13, -7,  4,-17, -5,-21,-14, 24,-16, -4, -6,  9,  4,-17,-30,-12, -4;
/M: SY='G'; M=  0,-10,-29,-10,-19,-30, 68,-20,-39,-20,-30,-20,  0,-20,-19,-20,  1,-19,-29,-21,-30,-19;
/M: SY='L'; M=-10,-30,-24,-34,-24,  6,-34,-24, 32,-30, 37, 20,-26,-26,-20,-24,-25,-10, 19,-20,  0,-24;
/M: SY='L'; M=-13,-28,-21,-34,-24, 26,-29,-17, 18,-25, 27, 23,-24,-27,-21,-19,-23,-10, 10,-12,  8,-22;
/M: SY='K'; M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='K'; M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='A'; M= 47,-10,-11,-20,-10,-20, -1,-19,-11, -8,-10,-10,-10,-10, -9,-16,  9,  0, -1,-20,-20,-10;
/M: SY='Y'; M=-16, -4,-28, -7, -6,  0,-19, 20,-16,  5,-15, -5,  1,-21,  1,  4,-11,-11,-19, -5, 26, -4;
/M: SY='E'; M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='L'; M=-10,-30,-22,-32,-22,  8,-32,-22, 25,-30, 45, 20,-28,-28,-20,-22,-28,-10, 14,-20,  0,-22;
/M: SY='S'; M= 13, -2,-10, -5, -4,-17, -5,-14,-15,-10,-22,-16,  4,-11, -4,-12, 31, 23, -5,-35,-18, -4;
/M: SY='V'; M= -2,-28,-13,-30,-28,  0,-30,-28, 28,-21, 14, 11,-27,-28,-27,-20,-11,  1, 41,-28, -8,-28;
/M: SY='L'; M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='C'; M= -8,-15, 90,-25,-25,-18,-28,-28,-25,-25,-18,-18,-15,-33,-25,-25, -3,  4, -8,-45,-25,-25;
/M: SY='D'; M=-14, 32,-30, 46, 12,-37,  7, -4,-38, -4,-29,-26, 13,-12,  0,-11,  0,-12,-30,-34,-22,  6;
/M: SY='A'; M= 34,-10, -1,-18,-11,-18, -6,-20,-10,-12,-12,-11, -9,-13,-11,-19, 12,  6,  1,-26,-19,-11;
/M: SY='E'; M=-11, 10,-29, 15, 37,-30,-18, -1,-29, 17,-23,-16,  4, -5, 19,  9, -1, -8,-27,-28,-16, 28;
/M: SY='V'; M= -3,-30,-16,-33,-30,  0,-33,-30, 36,-23, 13, 13,-27,-27,-27,-23,-13, -3, 44,-27, -7,-30;
/M: SY='A'; M= 20,-11, -8,-17,-11,-14, -4,-16, -8,-14, -6, -3, -8,-16, -9,-17,  8,  2, -2,-27,-16,-10;
/M: SY='L'; M= -7,-30,-18,-31,-24,  6,-31,-24, 26,-27, 37, 17,-29,-29,-23,-21,-24, -7, 23,-23, -3,-24;
/M: SY='I'; M= -9,-30,-24,-36,-27,  3,-36,-27, 39,-29, 27, 19,-24,-24,-21,-26,-21, -9, 27,-21, -1,-27;
/M: SY='I'; M= -6,-28,-21,-35,-28,  0,-33,-25, 37,-23, 17, 23,-24,-24,-20,-23,-17, -6, 34,-24, -4,-27;
/M: SY='F'; M=-11,-29,-19,-36,-27, 46,-29,-22, 11,-28, 17,  6,-22,-28,-32,-21,-19, -8, 10, -4, 14,-27;
/M: SY='S'; M= 13,  0,-12, -2, -3,-21,  5,-11,-21,-10,-28,-19,  9,-11, -3,-11, 33, 14,-11,-36,-21, -3;
/M: SY='S'; M= -2,  7,-20,  6, 11,-23, -7,  0,-23, -3,-27,-18, 13, -1,  3, -6, 17,  5,-21,-35,-18,  6;
/M: SY='T'; M= -2,  3,-17, -4, -3,-18,-11, -9,-19,  3,-20,-13,  9,-13,  0, 10, 13, 17,-12,-30,-14, -2;
/M: SY='G'; M= -4,  2,-28, -1,-13,-27, 45,-10,-34,-13,-28,-19, 12,-20,-13,-11,  1,-15,-29,-25,-25,-14;
/M: SY='K'; M=-11, -7,-27, -7,  2,-20,-22, -4,-20, 27,-13, -4, -5,-15,  4, 23,-12, -7,-14,-21, -7,  2;
/M: SY='L'; M= -8,-28,-18,-30,-23, 11,-29,-19, 20,-24, 32, 19,-28,-29,-21,-19,-22, -7, 18,-19,  2,-22;
/M: SY='Y'; M=-20,-16,-28,-18,-16, 22,-27, 37, -8,-14, -4,  1,-11,-27, -9, -9,-17,-13,-14,  6, 50,-16;
/M: SY='E'; M= -8, 12,-25, 17, 32,-27,-18,  0,-26,  3,-19,-17,  3, -5, 12, -3,  4,  4,-22,-30,-15, 22;
/M: SY='F'; M=-19,-26,-24,-31,-25, 55,-30, -3,  1,-22,  8,  1,-21,-30,-26,-16,-21,-10, -4, 17, 49,-25;
/M: SY='A'; M= 19, -8, -2,-14, -9,-16, -8,-15,-11,-13,-14,-11, -4,-14, -9,-16, 16, 11, -3,-30,-17, -9;
/M: SY='S'; M=  4,  3, -8, -3, -5,-17, -5,-12,-18,-10,-23,-17, 10,-12, -5,-10, 28, 26, -9,-36,-17, -5;
/M: SY='P'; M= -8, -7,-28, -4, -2,-22,-17,-12,-17, -5,-23,-15, -5, 31, -7, -8,  0,  1,-17,-29,-18, -7;
/M: SY='N'; M= -4, 10,-23, 11,  3,-27,  4, -8,-29,  7,-29,-19, 12,-12,  0,  0, 10,  0,-21,-31,-19,  2;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_12 which contains 556'388 sequence entries.


Total number of hits 192 in 192 different sequences
Number of true positive hits 192 in 192 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] MADS-box
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
192 sequences

1AP1_BRAOT  (Q96355    ), 2AP1_BRAOT  (Q96356    ), 3AP1_BRAOL  (Q39371    ), 
AG103_ARATH (Q9LSB2    ), AG104_ARATH (Q9LM46    ), AGL11_ARATH (Q38836    ), 
AGL12_ARATH (Q38841    ), AGL13_ARATH (Q38837    ), AGL14_ARATH (Q38838    ), 
AGL15_ARATH (Q38847    ), AGL15_BRANA (Q39295    ), AGL16_ARATH (A2RVQ5    ), 
AGL17_ARATH (Q38840    ), AGL18_ARATH (Q9M2K8    ), AGL19_ARATH (O82743    ), 
AGL1_ARATH  (P29381    ), AGL21_ARATH (Q9SZJ6    ), AGL23_ARATH (O80807    ), 
AGL24_ARATH (O82794    ), AGL27_ARATH (Q9AT76    ), AGL28_ARATH (Q9LMM8    ), 
AGL29_ARATH (O64703    ), AGL30_ARATH (Q1PFA4    ), AGL31_ARATH (Q9FPN7    ), 
AGL36_ARATH (Q7XJK6    ), AGL3_ARATH  (P29383    ), AGL42_ARATH (Q9FIS1    ), 
AGL49_ARATH (Q9ZUI9    ), AGL53_ARATH (Q7X9N2    ), AGL5_ARATH  (P29385    ), 
AGL61_ARATH (Q4PSU4    ), AGL62_ARATH (Q9FKK2    ), AGL63_ARATH (Q9SA07    ), 
AGL65_ARATH (Q7X9I0    ), AGL66_ARATH (Q1PFC2    ), AGL6_ARATH  (P29386    ), 
AGL70_ARATH (Q9LSR7    ), AGL71_ARATH (Q9LT93    ), AGL72_ARATH (Q9FLH5    ), 
AGL75_ARATH (Q9FLL0    ), AGL80_ARATH (Q9FJK3    ), AGL81_ARATH (Q9FIX0    ), 
AGL82_ARATH (Q9FIM0    ), AGL86_ARATH (Q9C6V3    ), AGL8_ARATH  (Q38876    ), 
AGL8_SINAL  (Q41274    ), AGL8_SOLCO  (O22328    ), AGL8_SOLLC  (Q40170    ), 
AGL8_SOLTU  (Q42429    ), AGL90_ARATH (Q7XJK5    ), AGL92_ARATH (Q9C6V4    ), 
AGL93_ARATH (Q7X9H9    ), AGL97_ARATH (Q9C633    ), AGL9_ARADE  (Q38694    ), 
AGL9_PETHY  (Q03489    ), AGL9_SINAL  (O04067    ), AGL9_SOLLC  (Q42464    ), 
AG_ARATH    (P17839    ), AG_BRANA    (Q01540    ), AG_PANGI    (Q40872    ), 
AG_PETHY    (Q40885    ), AG_SOLLC    (Q40168    ), AG_TOBAC    (Q43585    ), 
ANR1_ARATH  (Q9SI38    ), AP1A_BRAOA  (B4YPW6    ), AP1A_BRAOB  (Q8GTF5    ), 
AP1C_BRAOA  (B4YPV4    ), AP1C_BRAOB  (Q8GTF4    ), AP1_ARALL   (D7KWY6    ), 
AP1_ARATH   (P35631    ), AP1_BRARP   (P0DI14    ), AP1_CITSI   (A2IB53    ), 
AP1_SINAL   (Q41276    ), AP32_ASAEU  (Q9LLA7    ), AP3_ARATH   (P35632    ), 
ARGR1_YEAST (P07249    ), CALA_BRAOB  (Q6R4R9    ), CALB_BRAOB  (Q6R4R8    ), 
CALC_BRAOB  (Q6R4R7    ), CALD_BRAOB  (Q6R4R6    ), CAL_ARALL   (D7KQR8    ), 
CAL_ARATH   (Q39081    ), CAL_BRAOT   (Q39375    ), CAL_BRARC   (Q6R4S6    ), 
CAL_BRARP   (Q9SBK9    ), CAL_BRARR   (Q6R4S3    ), CMB1_DIACA  (Q39685    ), 
CMB2_DIACA  (Q42498    ), DEF21_ANTMA (Q8RVL4    ), DEFA_ANTMA  (P23706    ), 
EJ2_SOLLC   (Q7Y040    ), FBP1_PETHY  (Q03488    ), FBP24_PETHY (Q9ATE5    ), 
FLC_ARATH   (Q9S7Q7    ), GGM13_GNEGN (Q9XGJ4    ), GLOB_ANTMA  (Q03378    ), 
GLOB_TOBAC  (Q03416    ), J2_SOLLC    (K4DEK0    ), JOIN_SOLLC  (Q9FUY6    ), 
M17_MAIZE   (Q8VWM8    ), MAD13_ORYSJ (Q2QW53    ), MAD14_ORYSI (P0C5B1    ), 
MAD14_ORYSJ (Q10CQ1    ), MAD15_ORYSJ (Q6Q9I2    ), MAD16_ORYSJ (Q944S9    ), 
MAD17_ORYSJ (Q7XUN2    ), MAD18_ORYSI (A2YNI2    ), MAD18_ORYSJ (Q0D4T4    ), 
MAD20_ORYSJ (Q2QQA3    ), MAD21_ORYSJ (Q8RU31    ), MAD22_ORYSJ (Q9XJ66    ), 
MAD23_ORYSJ (Q6VAM4    ), MAD25_ORYSJ (Q84NC5    ), MAD26_ORYSI (A2YQK9    ), 
MAD26_ORYSJ (Q0J8G8    ), MAD27_ORYSJ (Q6EP49    ), MAD29_ORYSJ (Q6H711    ), 
MAD30_ORYSJ (Q655V4    ), MAD31_ORYSJ (Q84NC2    ), MAD32_ORYSJ (Q8S151    ), 
MAD33_ORYSJ (Q2QW55    ), MAD34_ORYSJ (Q6Q9H6    ), MAD47_ORYSJ (Q5K4R0    ), 
MAD50_ORYSJ (Q9XJ60    ), MAD51_ORYSJ (Q9XJ61    ), MAD55_ORYSJ (Q69TG5    ), 
MAD56_ORYSI (A2Z9Q7    ), MAD56_ORYSJ (P0C5B2    ), MAD57_ORYSJ (Q6Z6W2    ), 
MAD58_ORYSJ (Q2V0P1    ), MADS1_ORYSI (A2XDY1    ), MADS1_ORYSJ (Q10PZ9    ), 
MADS1_PETHY (Q07472    ), MADS2_ORYSJ (Q40702    ), MADS2_PETHY (Q07474    ), 
MADS3_ORYSJ (Q40704    ), MADS4_ORYSJ (Q40703    ), MADS4_SOLLC (K4BND8    ), 
MADS5_ORYSI (A2Y9P0    ), MADS5_ORYSJ (Q0DEB8    ), MADS6_ORYSJ (Q6EU39    ), 
MADS7_ORYSI (P0C5B0    ), MADS7_ORYSJ (Q0J466    ), MADS8_ORYSJ (Q9SAR1    ), 
MAF5_ARATH  (Q683D7    ), MBX1_SCHPO  (O42954    ), MCM1_CANAL  (Q5AFP3    ), 
MCM1_YEAST  (P11746    ), MEF2A_BOVIN (A2VDZ3    ), MEF2A_CHICK (Q9W6U8    ), 
MEF2A_HUMAN (Q02078    ), MEF2A_MOUSE (Q60929    ), MEF2A_PIG   (A2ICN5    ), 
MEF2A_PONAB (Q5REW7    ), MEF2A_RAT   (Q2MJT0    ), MEF2A_XENLA (Q03414    ), 
MEF2B_HUMAN (Q02080    ), MEF2B_MOUSE (O55087    ), MEF2C_BOVIN (Q2KIA0    ), 
MEF2C_HUMAN (Q06413    ), MEF2C_MOUSE (Q8CFN5    ), MEF2C_PIG   (A4UTP7    ), 
MEF2C_PONAB (Q5R444    ), MEF2C_RAT   (A0A096MJY4), MEF2D_HUMAN (Q14814    ), 
MEF2D_MOUSE (Q63943    ), MEF2D_RAT   (O89038    ), MEF2D_XENLA (Q03413    ), 
MEF2_DROME  (P40791    ), MTF1_PEA    (O65874    ), PHE1_ARATH  (O80805    ), 
PHE2_ARATH  (Q7XJK8    ), PIST_ARATH  (P48007    ), PMAP1_SCHPO (P78926    ), 
PVG4_SCHPO  (Q9HGP0    ), RLM1_YEAST  (Q12224    ), SEP1_ARATH  (P29382    ), 
SEP2_ARATH  (P29384    ), SEP3_ARATH  (O22456    ), SMP1_YEAST  (P38128    ), 
SOC1_ARATH  (O64645    ), SRFA_DICDI  (Q54TY7    ), SRFB_DICDI  (Q54RY6    ), 
SRFC_DICDI  (Q55F37    ), SRFD_DICDI  (Q54QY7    ), SRF_CHICK   (Q90718    ), 
SRF_DROME   (Q24535    ), SRF_HUMAN   (P11831    ), SRF_MOUSE   (Q9JM73    ), 
SRF_XENLA   (P23790    ), SVP_ARATH   (Q9FVC1    ), TT16_ARATH  (Q8RYD9    )
» more

PDB
[Detailed view]
12 PDB

1C7U; 1EGW; 1HBX; 1K6O; 1MNM; 1N6J; 1SRS; 1TQE; 3KOV; 3MU6; 3P57; 5F28

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission