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PROSITE entry PS50235


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50235
Entry name [info] USP_3
Accession [info] PS50235
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
01-DEC-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00750
Associated ProRule [info] PRU01035

Name and characterization of the entry

Description [info] Ubiquitin specific protease (USP) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=330;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=325;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9507669; R2=0.0143054; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=563; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=319; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-7; D=-75; I=-75; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 365 in 365 different sequences
Number of true positive hits 365 in 365 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] USP
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
365 sequences

CREB_ASPCL  (A1CIL1), CREB_ASPFC  (B0Y4P5), CREB_ASPFN  (B8NSV5), 
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PDB
[Detailed view]
182 PDB

1NB8; 1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2GFO; 2HD5; 2IBI; 2VHF; 2Y5B; 2Y6E;
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