PROSITE entry PS50800
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General information about the entry
| Entry name [info] | SAP |
| Accession [info] | PS50800 |
| Entry type [info] | MATRIX |
| Date [info] |
01-FEB-2003 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50800 |
| Associated ProRule [info] | PRU00186 |
Name and characterization of the entry
| Description [info] | SAP motif profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=35; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=32; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1756001; R2=0.0199757; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1162.7791748; R2=1.5220884; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=317; H_SCORE=1645; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=217; H_SCORE=1493; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105; M0=-8; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='L'; M=-11,-18,-24,-20, -8, 5,-27,-11, 6, -8, 10, 8,-18,-22,-11, -9,-17, -9, 3,-13, 8,-10; /M: SY='T'; M= 9, -6,-17,-11, -1,-16,-10,-14, -8, -9, -9, -3, -5,-11, -4,-13, 7, 11, -4,-26,-14, -3; /M: SY='S'; M= -4,-10,-24, -8, -2,-19, -4, -7,-14,-10,-13, -9, -5, -1, -6,-12, 3, -4,-14,-29,-15, -5; /M: SY='L'; M= -8,-25,-19,-28,-21, 9,-25,-13, 16,-21, 25, 23,-23,-26,-15,-16,-18, -6, 12,-18, 4,-18; /M: SY='T'; M= -4, -5, -7,-10, -6,-17,-17,-14,-17, 3,-18,-11, -1,-15, -3, 8, 10, 15, -8,-30,-13, -6; /M: SY='V'; M= -2,-14,-18,-15,-12, -8,-24,-15, 9,-12, 0, 4,-16,-21, -9,-14, -6, 0, 15,-23, -3,-11; /M: SY='S'; M= 4, -2,-16, -3, 2,-20, -9, -4,-20, -5,-23,-16, 4, -5, 0, -3, 21, 14,-13,-33,-15, 0; /M: SY='E'; M= -3, 5,-25, 9, 23,-22,-17, -6,-21, 4,-16,-13, -2, -9, 10, -4, -1, -8,-17,-25,-14, 17; /M: SY='L'; M=-10,-30,-22,-32,-22, 8,-32,-22, 27,-30, 43, 20,-28,-28,-20,-22,-28,-10, 14,-20, 0,-22; /M: SY='R'; M=-14, -4,-30, -4, 8,-28,-20, 0,-27, 30,-23, -7, 0,-14, 24, 42, -7,-10,-23,-20,-10, 14; /M: SY='D'; M= -8, 12,-24, 17, 2,-26, -8, -8,-19, -4,-19,-11, 4,-13, 0, -8, 4, -2,-13,-31,-16, 1; /M: SY='M'; M= -1,-15,-22,-19, -8, -4,-23,-16, 2, -4, 5, 6,-13,-17, -9, -8,-11, -5, 0,-19, -5, -9; /M: SY='C'; M= -5,-25, 24,-29,-22, -2,-27,-23, 2,-28, 23, 5,-25,-31,-22,-23,-20, -9, 3,-29,-11,-22; /M: SY='R'; M= -6, -2,-26, 0, 10,-26, -5, -6,-28, 16,-26,-14, 2,-12, 9, 18, 4, -5,-21,-26,-16, 9; /M: SY='E'; M= 2, -4,-22, -4, 9,-15,-15, -1,-17, 3,-17,-10, -3,-12, 5, -2, 3, -4,-13,-22, -6, 7; /M: SY='R'; M= -9,-14,-22,-17, -9, -1,-22, -9, -2, -5, 5, 4,-11,-23, -8, 6,-13, -7, 0,-19, -1,-10; /M: SY='G'; M= 2, -8,-27, -8,-17,-28, 59,-18,-37,-18,-30,-20, 2,-18,-17,-18, 7,-13,-27,-23,-28,-17; /M: SY='L'; M=-11,-25,-21,-26,-16, 8,-28,-16, 11,-19, 30, 13,-24,-27,-13, -7,-23, -9, 6,-18, 0,-15; /M: SY='S'; M= -1, -1,-23, 0, 1,-24, -9, -9,-23, -1,-26,-18, 3, 10, -1, 4, 11, 2,-18,-32,-20, -2; /M: SY='T'; M= 1, -7, -4,-13,-10,-13,-19,-10,-11, -7,-10, -7, -5,-16, -9, -8, 7, 19, -2,-30,-10,-10; /M: SY='N'; M= -5, 11,-21, 7, 1,-23, -3, 9,-23, -6,-26,-16, 18, -7, 2, -6, 13, 4,-22,-34,-15, 0; /M: SY='G'; M= 1, -9,-28, -9,-18,-29, 65,-19,-38,-19,-30,-20, 1,-19,-18,-19, 3,-17,-28,-22,-29,-18; /M: SY='R'; M= -8, -6,-25, -8, -5,-19,-11, -6,-18, 2,-18,-10, -1, 0, -4, 5, -1, 0,-14,-27,-14, -6; /M: SY='K'; M=-12, -1,-30, 0, 12,-28,-20, -8,-30, 44,-28,-11, 0,-11, 11, 34, -9,-10,-21,-21,-11, 11; /M: SY='Q'; M= 1, -7,-25, -9, 2,-26,-16, 5,-18, 6,-17, -5, -5, -6, 16, 8, -3, -8,-16,-23,-10, 7; /M: SY='E'; M=-12, 0,-25, 3, 12,-14,-21, 3,-12, -3, -6, -7, -2,-16, 0, -1, -8, -8,-11,-25, -5, 5; /M: SY='L'; M= -9,-29,-20,-31,-22, 7,-30,-20, 23,-27, 42, 23,-28,-28,-19,-20,-27, -9, 15,-21, -1,-21; /M: SY='I'; M= -8,-20,-11,-24,-13, -8,-30,-19, 15,-19, 11, 8,-18,-22, -7,-17,-13, -5, 10,-25, -7,-12; /M: SY='D'; M=-11, 11,-25, 15, 8,-26,-19, -8,-19, 6,-18,-12, 2,-12, 4, 2, -1, 1,-13,-29,-13, 5; /M: SY='R'; M=-12,-13,-15,-15, -6,-17,-21, -8,-20, 16,-12, -7, -7,-22, 0, 40,-10, -9,-11,-23,-11, -6; /M: SY='L'; M= -6,-16,-14,-19,-16, -4,-26, -2, 7,-21, 12, 6,-15,-24,-13,-19,-16,-10, 2,-21, 4,-17; /M: SY='R'; M= -2, -5,-21,-10, -6,-14,-17,-11,-10, 6, -5, -4, 0,-19, -5, 9, -6, -2, -6,-24,-11, -6; /M: SY='E'; M=-10, 8,-27, 10, 16,-29, -8, 12,-29, 10,-25,-13, 9,-11, 13, 4, 1, -9,-26,-28,-12, 14; /M: SY='Y'; M= -4,-20,-26,-23,-18, 5,-15, 3, -7,-18, 0, -2,-17,-24,-14,-15,-16,-13, -7, 11, 16,-17; /M: SY='L'; M= -8,-16,-21,-18, -6, -1,-27,-17, 7,-12, 10, 7,-16,-18,-11,-12,-11, 1, 7,-23, -5, -9; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 123 in 120 different sequences |
| Number of true positive hits | 123 in 120 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 24 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 83.67 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | SAP |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
120 sequences
049L_FRG3G (Q6GZS7), ACINU_HUMAN (Q9UKV3), ACINU_MOUSE (Q9JIX8), AIM34_EREGS (Q75CC0), AIM34_KLULA (Q6CUC1), AIM34_LACTC (C5DEP0), AIM34_YARLI (Q6CFD4), AIM34_YEAS1 (B3LLQ4), AIM34_YEAS2 (C7GLB5), AIM34_YEAS6 (B5VPC6), AIM34_YEAS7 (A6ZM65), AIM34_YEAS8 (C8ZEK9), AIM34_YEAST (Q03673), AIM34_ZYGRC (C5DTC6), ARP_ARATH (P45951), CCAR1_HUMAN (Q8IX12), CCAR1_MOUSE (Q8CH18), CCAR1_XENLA (Q641G3), CCE1_SCHPO (Q10423), DPPA2_HUMAN (Q7Z7J5), ERI1_CAEEL (O44406), ERI1_HUMAN (Q8IV48), ERI1_MOUSE (Q7TMF2), ERI1_RAT(Q5FVR4), ERI1_SCHPO (Q08I43), HNRL1_HUMAN (Q9BUJ2), HNRL1_MOUSE (Q8VDM6), HNRL2_HUMAN (Q1KMD3), HNRL2_MOUSE (Q00PI9), HNRPU_HUMAN (Q00839), HNRPU_MOUSE (Q8VEK3), HNRPU_RAT (Q6IMY8), KU70_ARATH (Q9FQ08), KU70_ASPOR (Q2MHH4), KU70_ASPSO (Q2MHH3), KU70_CHAGB (Q2H0I3), KU70_COCIM (Q1DU75), KU70_EMENI (Q5AVC7), KU70_NEUCR (Q7SA95), KU70_ORYSJ (Q7F1M0), KU70_PHANO (Q0U5F2), KU70_RHIAP (Q26228), KU70_SCHPO (O94395), LOT1_ARATH (Q6IDA6), MASTR_BOVIN (A7E346), MASTR_HUMAN (Q6ZN01), MASTR_MOUSE (Q0ZCJ7), MRTFA_HUMAN (Q969V6), MRTFA_MOUSE (Q8K4J6), MRTFA_XENLA (Q8AYC2), MRTFB_HUMAN (Q9ULH7), MRTFB_MOUSE (P59759), MRTFB_XENLA (Q8AYC1), MYCD_HUMAN (Q8IZQ8), MYCD_MOUSE (Q8VIM5), MYCD_PIG(Q7YR76), MYCD_RAT(Q8R5I7), PARP1_MAIZE (Q9ZSV1), PARP1_ORYSJ (Q7EYV7), PARP2_ARATH (Q11207), PARP2_MAIZE (O50017), PARP3_SOYBN (Q9SWB4), PHM2_CAEEL (O62203), PIAS1_HUMAN (O75925), PIAS1_MOUSE (O88907), PIAS2_HUMAN (O75928), PIAS2_MOUSE (Q8C5D8), PIAS2_RAT (Q6AZ28), PIAS3_HUMAN (Q9Y6X2), PIAS3_MOUSE (O54714), PIAS3_RAT (O70260), PIAS4_HUMAN (Q8N2W9), PIAS4_MOUSE (Q9JM05), PIS4A_DANRE (F1R4C4), PLI1_SCHPO (O94451), PRP2A_ORYSJ (Q5Z8Q9), RAD18_ASPFU (Q4WZJ6), RAD18_CANAL (Q5A4N5), RAD18_CANGA (Q6FPI4), RAD18_DEBHA (Q6BLM3), RAD18_EMENI (Q02398), RAD18_EREGS (Q75EN0), RAD18_HUMAN (Q9NS91), RAD18_KLULA (Q6CTZ8), RAD18_MOUSE (Q9QXK2), RAD18_NEUCR (P33288), RAD18_SCHPO (O74747), RAD18_YARLI (Q6CHI1), RAD18_YEAST (P10862), RRC1_ARATH (Q9C5J3), SAFB1_HUMAN (Q15424), SAFB1_MOUSE (D3YXK2), SAFB1_PONAB (Q5R452), SAFB1_RAT (O88453), SAFB2_HUMAN (Q14151), SAFB2_MOUSE (Q80YR5), SARNP_HUMAN (P82979), SARNP_MOUSE (Q9D1J3), SARNP_PONAB (Q5R4V4), SARNP_RAT (Q498U4), SF3B2_HUMAN (Q13435), SF3B2_MOUSE (Q3UJB0), SIZ1_ARATH (Q680Q4), SIZ1_ORYSJ (Q6L4L4), SIZ1_YEAST (Q04195), SIZ2_ORYSJ (Q6ASW7), SIZ2_YEAST (Q12216), SLTM_HUMAN (Q9NWH9), SLTM_MOUSE (Q8CH25), SLTM_XENLA (Q498L2), THO1_YEAST (P40040), XRCC6_CHICK (O93257), XRCC6_HUMAN (P12956), XRCC6_MOUSE (P23475), Y0785_DICDI (Q54UW0), Y0787_DICDI (Q54UV9), Y0809_DICDI (Q54UV8), Y1095_DICDI (Q54UG3), Y1301_DICDI (Q54UG2), YCW3_SCHPO (O74871)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
24 sequences
C3H62_ORYSJ (Q338N2), DEK_HUMAN (P35659), DEK_MOUSE (Q7TNV0), DEK_RAT (Q6AXS3), DPPA2_MOUSE (Q9CWH0), KU70_DICDI (Q54MA9), NEW25_SCHPO (G2TRT4), PARP3_MEDTR (Q1SGF1), RFFL_HUMAN (Q8WZ73), RFFL_MOUSE (Q6ZQM0), RFFL_RAT(Q8CIN9), RNF34_BOVIN (Q5E9J6), RNF34_HUMAN (Q969K3), RNF34_MOUSE (Q99KR6), RNF34_PONAB (Q5NVC7), RNF34_RAT (Q6AYH3), RRC1L_ARATH (F4KIA8), SDE2_DANRE (Q7T293), SDE2_HUMAN (Q6IQ49), SDE2_MOUSE (Q8K1J5), SDE2_PONAB (Q5RET9), SDE2_RAT(Q5BJN8), SDE2_XENLA (Q6NRI5), SDE2_XENTR (Q07G43)» more |
| PDB [Detailed view] |
91 PDB
1H1J; 1JEQ; 1JEY; 1JJR; 1KCF; 1V66; 1ZBH; 1ZBU; 1ZRJ; 2DO1; 2DO5; 2JX3; 2KVU; 2KW9; 2RNN; 2RNO; 2WQG; 4L8R; 4QOZ; 4UZW; 5Z56; 5Z57; 5Z58; 6AH0; 6AHD; 6FF4; 6FF7; 6QX9; 6Y50; 6Y53; 6Y5Q; 6ZHA; 6ZHE; 7ABG; 7ABH; 7ABI; 7AXZ; 7DVQ; 7EVO; 7K0Y; 7K1J; 7K1K; 7K1N; 7LSY; 7LT3; 7NFC; 7NFE; 7ONB; 7Q3L; 7Q4O; 7Q4P; 7QTT; 7SGL; 7SU3; 7VPX; 7Z6O; 7Z87; 7Z88; 7ZT6; 7ZVT; 7ZWA; 7ZYG; 8AG4; 8AG5; 8BH3; 8BHV; 8BHY; 8BOT; 8CH6; 8EZA; 8EZB; 8H6E; 8H6J; 8H6K; 8H6L; 8HK1; 8I0P; 8I0R; 8I0S; 8I0T; 8I0U; 8I0V; 8QO9; 8QXD; 8QZS; 8R08; 8R09; 8R0A; 8R0B; 8RM5; 8Y7E » more |