PROSITE entry PS50865
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General information about the entry
| Entry name [info] | ZF_MYND_2 |
| Accession [info] | PS50865 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JAN-2003 CREATED;
13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50865 |
| Associated ProRule [info] | PRU00134 |
Name and characterization of the entry
| Description [info] | Zinc finger MYND-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=38; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=35; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2840000; R2=0.0086421; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1470.3616943; R2=3.8778980; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=835; H_SCORE=4708; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=604; H_SCORE=3813; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-9; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='C'; M=-10,-11, 99,-22,-25,-20,-25,-24,-28,-25,-22,-20, -8,-37,-25,-25, -7, -8,-13,-48,-28,-25; /M: SY='Y'; M= -5, -9,-24,-12,-11, -4,-17, 0,-13, -8,-10, -8, -7,-20, -9, -4, -7, -3,-11, 4, 7,-11; /M: SY='N'; M= -8, 0,-23, -6, -7,-10,-11, -5, -9, -7,-13, -9, 7,-20, -5, -8, -1, -2,-10,-15, -2, -6; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='G'; M= -5, -5,-26, -7,-12,-12, 30,-15,-26,-17,-17,-14, 2,-20,-16,-16, -2,-13,-22,-21,-18,-14; /M: SY='R'; M= -7, 1, -8, -4, 1,-22,-16, -8,-25, 15,-23,-14, 6,-16, 1, 18, 0, 0,-17,-29,-15, 0; /M: SY='W'; M= -8,-10,-28, -8, 5,-11,-12,-13,-21, -2,-18,-15, -9,-15, -2, -3, -2, -5,-19, 9, -5, 2; /M: SY='A'; M= 17, -4,-11, -8, 4,-23,-10,-12,-17, -1,-16,-10, -3, -7, 1, -9, 4, -4,-12,-26,-19, 2; /I: I=-4; MD=-21; /M: SY='T'; M= 1, -3,-18, -5, -2,-14, -9,-11, -8, -9, -7, -3, -2, -7, -5,-11, 2, 4, -7,-25,-13, -4; D=-4; /I: I=-4; MD=-21; /M: SY='Y'; M= -6, -3,-18, -2, 2, -4,-13, 1,-14, 2,-13, -8, -3, -6, -2, -2, -2, -4,-12,-12, 3, 0; D=-4; /I: I=-4; MI=0; MD=-21; IM=0; DM=-21; /M: SY='K'; M= 3, -4,-14, -6, 0,-13, -9, 0, -9, 7, -7, 1, -4, -8, 4, 2, -4, -5, -7,-12, -5, 2; D=-4; /I: I=-4; DM=-21; /M: SY='K'; M= -8, -3,-24, -4, 5,-21,-20, 0,-22, 18,-17, -8, -1,-13, 4, 18, -3, 2,-15,-24, -8, 3; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /I: I=-6; MD=-29; /M: SY='S'; M= 3, -4,-16, -5, -1,-17, 1,-10,-19, -4,-18,-13, 2,-12, -2, 1, 16, 6,-11,-28,-16, -2; D=-6; /I: I=-6; MI=-29; MD=-29; IM=-29; DM=-29; /M: SY='R'; M= -4, -9,-24,-10, -4,-15, 4, -9,-23, 4,-15, -9, -4,-16, -1, 14, -5,-10,-17,-17,-12, -4; D=-6; /I: I=-6; DM=-29; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='R'; M=-13, -2,-31, -5, 1,-21,-12, 1,-25, 16,-24,-10, 4,-17, 11, 19, -8,-12,-25, -4, -3, 5; /M: SY='R'; M=-10, 1,-21, -4, -6, -8,-17, -6,-13, 3,-15, -7, 7,-19, -3, 10, -1, 1, -9,-25, -8, -4; /M: SY='A'; M= 17,-11,-12,-16,-10,-12,-15,-21, -2,-12, -5, -5,-11,-15,-13,-16, 8, 15, 9,-27,-14,-11; /M: SY='R'; M= -4,-12,-27,-13, -5,-17,-16, 0,-19, 9,-18, -7, -8,-13, 0, 14, -8,-10,-14, -4, -5, -4; /M: SY='Y'; M=-20,-20,-30,-20,-20, 30,-30, 20, 0,-10, 0, 0,-20,-30,-10,-10,-20,-10,-10, 30, 80,-20; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='S'; M= 6, 1, -6, 1, -3,-22, 5,-12,-24,-12,-29,-21, 8,-13, -4,-12, 31, 12,-13,-38,-22, -3; /M: SY='K'; M= -4, -6,-25, -7, 3,-24,-18,-10,-18, 17,-20, -9, -3, -7, 7, 15, -1, -3,-12,-24,-13, 4; /M: SY='E'; M= -6, 2,-25, 6, 25,-13,-18, -7,-23, 6,-18,-15, -1, -8, 4, -1, 1, -3,-19,-24,-11, 15; /M: SY='C'; M=-12,-16, 86,-23,-23,-20,-28, -1,-30,-26,-20,-16,-13,-36,-21,-23,-10,-12,-14,-46,-19,-23; /M: SY='Q'; M=-10, 0,-30, 0, 20,-40,-20, 10,-20, 10,-20, 0, 0,-10, 60, 10, 0,-10,-30,-20,-10, 40; /M: SY='R'; M= -5,-10,-23,-11, -3,-18,-20, 2,-12, 7,-11, -2, -7,-18, 6, 11, -6, -5, -7,-21, -4, 0; /M: SY='K'; M= 0, -6,-22, -7, 0,-19,-13,-13,-13, 3, -8, -6, -5,-14, 0, 0, -2, -3, -9,-24,-12, -1; /M: SY='D'; M= -1, 22,-24, 27, 10,-29,-10, 16,-29, -4,-22,-18, 11,-12, 1, -9, 1, -9,-22,-32,-12, 4; /M: SY='W'; M=-20,-40,-50,-40,-30, 10,-20,-30,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,150, 30,-20; /M: SY='E'; M=-10, -5,-27, -3, 4,-19,-15, -4,-17, 2,-10, -7, -4, -5, 2, 4, -7, -8,-17,-26,-12, 2; /I: I=-6; MI=0; MD=-29; IM=0; DM=-29; /M: SY='G'; M= -1, -5,-22, -7, -8,-15, 4,-12,-17, -7,-12,-10, -3,-18,-10,-10, -1, -3,-12,-20, -8, -9; /M: SY='H'; M=-20, 0,-30, 0, 0,-20,-20,100,-30,-10,-20, 0, 10,-20, 10, 0,-10,-20,-30,-30, 20, 0; /M: SY='R'; M=-12, -3,-29, -3, 6,-27,-14, 4,-29, 28,-25, -9, 1,-14, 14, 30, -5,-10,-22,-22, -9, 8; /M: SY='H'; M=-13, -3,-26, -3, 1,-17,-20, 9,-15, 4,-12, -2, -2,-12, 5, 8, -7, -7,-13,-24, -3, 1; /M: SY='E'; M= -7, -8,-28, -9, 11,-10,-22,-14, -9, -7,-10,-10, -9,-13, -3,-12, -7, -5,-11, 1, -5, 4; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 102 in 102 different sequences |
| Number of true positive hits | 102 in 102 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 11 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 90.27 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | N_Hulo |
| Feature key [info] | ZN_FING |
| Feature description [info] | MYND-type |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
102 sequences
AJM1_CAEEL (A0A1C3NSL9), ANKY1_HUMAN (Q9P2S6), ANKY2_BOVIN (Q0VCS9), ANKY2_CHICK (Q5ZMD2), ANKY2_HUMAN (Q8IV38), ANKY2_MOUSE (Q3TPE9), ANMY1_MOUSE (Q8C0W1), ASHR1_ARATH (Q7XJS0), DAF25_CAEEL (Q9N3Q8), DEAF1_DROME (Q24180), DEAF1_HUMAN (O75398), DEAF1_MOUSE (Q9Z1T5), DEAF1_PANTR (O77562), DEAF1_RAT (O88450), EGL9_CAEEL (G5EBV0), EGLN1_HUMAN (Q9GZT9), EGLN1_MOUSE (Q91YE3), FB342_ARATH (Q9FK27), FB76_ARATH (Q9FYF9), GACZ_DICDI (Q55DW9), MSS51_HUMAN (Q4VC12), MSS51_MOUSE (Q9D5Z5), MSS51_RAT (D3ZKV9), MTG16_CHICK (Q5F3B1), MTG16_HUMAN (O75081), MTG16_MOUSE (O54972), MTG8R_HUMAN (O43439), MTG8R_MOUSE (O70374), MTG8R_XENLA (Q9IAB2), MTG8_HUMAN (Q06455), MTG8_MOUSE (Q61909), MUB1_ASPCL (A1CBG9), MUB1_ASPFC (B0Y1D1), MUB1_ASPFN (B8NKS1), MUB1_ASPFU (Q4WVI6), MUB1_ASPNC (A2RA63), MUB1_ASPOR (Q2U685), MUB1_ASPTN (Q0CW83), MUB1_EMENI (O42631), MUB1_NEOFI (A1DDX0), MUB1_SCHPO (P87311), MUB1_YEAST (Q03162), PDCD2_BOVIN (Q2YDC9), PDCD2_HUMAN (Q16342), PDCD2_MOUSE (P46718), PDCD2_RAT (P47816), SET14_CAEEL (Q09415), SET6_SCHPO (O94256), SMY2A_DANRE (Q5BJI7), SMY2A_XENLA (Q7ZXV5), SMY2B_DANRE (Q5RGL7), SMY2B_XENLA (Q6GN68), SMYD1_HUMAN (Q8NB12), SMYD1_MOUSE (P97443), SMYD2_BOVIN (Q0P585), SMYD2_CHICK (E1C5V0), SMYD2_HUMAN (Q9NRG4), SMYD2_MOUSE (Q8R5A0), SMYD2_PIG (C3RZA1), SMYD2_RAT (Q7M6Z3), SMYD3_HUMAN (Q9H7B4), SMYD3_MOUSE (Q9CWR2), SMYD4_CHICK (Q5F3V0), SMYD4_DANRE (Q08C84), SMYD4_HUMAN (Q8IYR2), SMYD4_MOUSE (Q8BTK5), SMYD4_PONAB (Q5R5X9), SMYDL_CAEEL (Q8I4F7), TDRD1_DANRE (Q58EK5), TDRD1_HUMAN (Q9BXT4), TDRD1_MOUSE (Q99MV1), TDRD1_ORYLA (A9CPT4), UBP15_ARATH (Q9FPS9), UBP15_ORYSJ (Q0E2F9), UBP16_ARATH (Q9SB51), UBP17_ARATH (Q9FKP5), UBP18_ARATH (Q67XW5), UBP19_ARATH (Q9SJA1), UBP19_HUMAN (O94966), UBP19_MOUSE (Q3UJD6), UBP19_RAT (Q6J1Y9), Y2140_DICDI (Q54DL6), Y2454_DICDI (Q54D67), Y4059_DICDI (Q54Q80), Y7331_DICDI (Q54ZX8), YR331_MIMIV (Q5UQS2), ZMY10_DANRE (F1QN74), ZMY10_DROME (Q9VU41), ZMY10_HUMAN (O75800), ZMY10_MOUSE (Q99ML0), ZMY10_RAT (Q6AXZ5), ZMY10_XENLA (Q5FWU8), ZMY11_HUMAN (Q15326), ZMY11_MOUSE (Q8R5C8), ZMY12_HUMAN (Q9H0C1), ZMY15_HUMAN (Q9H091), ZMY15_MOUSE (Q8C0R7), ZMY19_HUMAN (Q96E35), ZMY19_MOUSE (Q9CQG3), ZMY19_RAT (Q7TSV3), ZMYD8_DROME (Q7KRS9), ZMYD8_HUMAN (Q9ULU4)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
11 sequences
ATXR2_ARATH (Q5PP37), BIG_ARATH (Q9SRU2), BIG_ORYSJ (B9G2A8), SMYD5_CHICK (Q5ZIZ2), SMYD5_DANRE (F1RET2), SMYD5_HUMAN (Q6GMV2), SMYD5_MOUSE (Q3TYX3), SMYD5_XENLA (Q6GPQ4), Y3589_DICDI (Q557F7), Y3591_DICDI (Q557F6), Y8495_DICDI (Q54IV4)» more |
| PDB [Detailed view] |
69 PDB
2D8Q; 2DAN; 2DJ8; 2JW6; 2OD1; 2ODD; 3MEK; 3N71; 3OXF; 3OXG; 3OXL; 3PDN; 3QWP; 3QWV; 3QWW; 3RIB; 3RU0; 3S7B; 3S7D; 3S7F; 3S7J; 3TG4; 3TG5; 4A24; 4O6F; 4WUY; 4YND; 5ARF; 5ARG; 5CCL; 5CCM; 5EX0; 5EX3; 5HDA; 5HI7; 5HQ8; 5KJK; 5KJL; 5KJM; 5KJN; 5MQ4; 5V37; 5V3H; 5WCG; 5XXD; 5XXG; 5XXJ; 5YJO; 6CBX; 6CBY; 6IJL; 6MON; 6N3G; 6O9O; 6P6G; 6P6K; 6P7Z; 6PAF; 6YUH; 6ZRB; 7BJ1; 7O2A; 7O2B; 7O2C; 7QLB; 7QNR; 7QNU; 8J07; 8OWO » more |