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Entry: PS51185

General information about the entry

Entry name [info] WHEP_TRS_2
Accession [info] PS51185
Entry type [info] MATRIX
Date [info] 01-MAR-2006 CREATED; 10-MAY-2017 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00614
Associated ProRule [info] PRU00531

Name and characterization of the entry

Description [info] WHEP-TRS domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=57;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=57;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4966421; R2=0.0045687; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6032.1479492; R2=2.9600921; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1315; H_SCORE=9925; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=877; H_SCORE=8628; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-100; I=-100; B1=-500; E1=-500; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='D'; M= -1,-49, 46, 16,-51,  0,-19,-22, 10,-28,-16,-16,-21, 27, -4, 35, -1,-37,-57,-42;
/M: SY='L'; M= 17,-35,-21,-14,-36,-12,-31, 18, -2, 23,-24,-40, 17,-29, 11, -2,-21, 20,-52,-31;
/M: SY='A'; M= 43,-45,  4, 20,-46,-22,-37,-38, 28,  2,  5, -4,-22,  8,-29,  3,-16,-22,-53,-42;
/M: SY='E'; M= 37,-23, 31, 41,-53,-33,-36,-41,-22,-34,-41,-22, 35, 17,-36,  6, -3,-19,-57,-46;
/M: SY='L'; M=  1,-45,-35,-31,-13,-56,-45, 30,-27, 64, -5,-51,-37,-43,-28,-45,-23, -3,-48,-31;
/M: SY='Y'; M=-15,-51,-27, 29, 11,-47,-29,-38,-23, -1, -4, -4,-46, 28, 40, -6,  6,-28, 18, 47;
/M: SY='E'; M= 21,-47, 32, 36,-48,-32, -9,-42, 20, -1,-36, 21,-41, 20,-29,  6, -9,-27,-56,-42;
/M: SY='E'; M= 35,-19,-30, 37,-49,-39,-35,-16, 29,-17,-35,-20,-41, 30, 15, 10,-30,-15,-52,-42;
/M: SY='V'; M=-29,-47,-58,-53,-27,-61,-58, 64,-47, -1,-15,-52,-52,-49,-10,-44,-30, 66,-56,-35;
/M: SY='A'; M= 36,-47, 12, 27,-52,-38,-34,-22, 32,-45,-39, 16,-40, 23, 14,-21, 15,-24,-55,-43;
/M: SY='E'; M= 32,-23, -1, 53,-51,-40,-23,-33, 11,-20,-37,-31,-39, 44,-28,  2,-14, -8,-54,-43;
/M: SY='Q'; M=-35,-59,-31,-12,-57,-44,-23,-47, -6,-30,  3,-27,-43,112, 10,-26,-37,-50,-46, -7;
/M: SY='G'; M= 11,-50,  7,-44,-57, 86,-13,-62,-43,-59,-49,-25,-43,-40,-50,-24,-41,-55,-51,-51;
/M: SY='D'; M=  3,-50, 70, 48,-55,-31,-29,-51,-26,-27,-46, 47,-41,-19,-20,-28,-15,-40,-65,-46;
/M: SY='K'; M= 10,-46,-41,  4,-17,-49,  3, -5, 42, 37,-21,-33,-47,-23,-16,-36,-19, 20,-50,-35;
/M: SY='V'; M=-17,-42,-58,-52,-29,-59,-61, 29,-50,-14,-17,-53,-53,-52,-52,-41,-27, 86,-62,-37;
/M: SY='R'; M=-11,-57,-38,-26,-52,-50,-28,-57,  2,-50,-39,-32,-50, 12,101,-34,-40,-50,-51,-38;
/M: SY='K'; M= -5,-52, 41, 34,-56,-12,-31,-53, 45,-51,-43,-24,-39, 41, 16,  3,-12,-38,-55,-43;
/M: SY='L'; M=-13,-44,-59,-51,-18,-59,-44,  7,-52, 77,  4,-57,-58,-45,-50,-50,-37, -7,-47,-30;
/M: SY='K'; M=-38,-53,-31,-17,-54,-45,-33,-55, 96,-53,-41,-23,-39,-15, 17,-32,-33,-50,-48,-41;
/M: SY='A'; M= 57,-42,-34, 15,-51, 16,-39,-42,-33,-44,-16,-22,-40, 16,-38, 29,  4,-13,-53,-45;
/M: SY='E'; M= 31,-48, 17, 43,-56,-16,-33,-51, 39,-50,-42,-13,-38, 33,-13, 10,-15,-44,-53,-44;
/M: SY='K'; M=-36,-51, 26,-20,-55, 17,-32,-55, 76,-55,-44, 28,-40, -5,  1,-29, -7,-51,-53,-43;
/M: SY='A'; M= 75,-39,-19,-24,-51,-20,-42,-42,-11,-44,-38,-16, -6,-32,-39, 13,  0,-27,-53,-46;
/M: SY='P'; M= 16,-50, 35, 23,-56,-35,-36,-51, 16,-54,-46,-27, 61,-26,-33, 44,-26,-46,-57,-47;
/I:         I=-26; MD=-65;
/M: SY='K'; M= -6,-51, -6,  1,-55,-41,-35,-51, 71,-51,-10,-26, 22, 20, -3, 17, -9,-47,-52,-43; D=-26;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='E'; M= 20,-49, 35, 42,-52,-13,-34,-12,-28,-38,-39,  2, -6, 37,-35, 14, -3, -9,-57,-44;
/M: SY='E'; M=  3,-50, 42, 49,-49,-41,-35,-21,  6,-19,-36,-29,-40, 39,-30,-29,  7, 16,-58,-42;
/M: SY='W'; M=-18,-48,-57,-53,-27,-57,-58, 66,-49,  1,-17,-49,-50,-48,-53,-19,  9, 46, 67,-31;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='D'; M= -1,-51, 74, 10,-57,-30,-31,-53, 40,-53,-47,  4,-40, 19,-24,-22, 16,-48,-62,-44;
/M: SY='A'; M= 42,-48, 25, 34,-54,-29,-37,-36, 19,-48,-41,-30, 33,  3, -8,  7,-30,-21,-55,-46;
/M: SY='A'; M= 68,-43,-27, 57,-54,-33,-38,-47,-28,-46,-40,-35,-38,-14,-13,-13,-30,-35,-53,-47;
/M: SY='V'; M=-30,-43,-59,-54,-28,-61,-61, 44,-51,-13,-16,-53,-53,-52,-53,-43,-27, 83,-60,-36;
/M: SY='A'; M= 45,-45, -3,  8,-53, -7,-35,-46, 43,-48,-40, 33,-41, 17,-24,-15,  0,-24,-54,-44;
/M: SY='K'; M=-15,  9,-30, 33,-46,-47,-35,  2, 60,-13, 23,-12,-40, 19, -8,-32,  9,-26,-51,-40;
/M: SY='L'; M=-42,-44,-60,-52,-16,-61,-43, -7,-53, 81, 16,-59,-59,-46,-50,-53,-38,-15,-46,-28;
/M: SY='L'; M=-41,-46,-49,-41,-23,-55,-40,-15, 33, 69,-11, -7,-54,-37,-33,-31,-36,-17,-48,-32;
/M: SY='A'; M= 42,-46, 25, 36,-53,-35,-35,-31, 21,-47,-41,-24,-39, 20,-29, 31,-15,-27,-55,-44;
/M: SY='L'; M=-12,-46,-54,-46,-21,-35,-40,-14,-20, 70, 10,-51,-56,-39, 19,-46,-38,-20,-46,-13;
/M: SY='K'; M=-38,-52,-29,  3,-54,-45,-33,-55, 96,-53,-41,-23,-38,-15,  0,-32,-33,-50,-48,-41;
/M: SY='K'; M= 46,-44,-35, -8,-46,-31,-18,-38, 47,-10, 14, 18,-43,-13,  8,-26, -9,-13,-52,-41;
/M: SY='Q'; M=-13,-51, 17, 39,-41,-42,  1,-37, 14,-17,-36,  4,-40, 67,-25, 10,  7,-20,-54,-39;
/M: SY='Y'; M=-32,-50,-52,-49, 29,-56,-28,-19,-18, 50,-15,-51,-58,-41,-42,-46,-39,-16,-21, 86;
/M: SY='K'; M= 16,-19,-16, 30,-54, 17,-36,-53, 68,-41,-42,-27,-39, -5,-15, -3,-32,-46,-50,-44;
/M: SY='E'; M= 27,-47, 23, 31,-51, 15, 22,-47,  2,-21,-40,-16,-22, -2,-11, 14, 12,-36,-56,-42;
/M: SY='V'; M= 33,-44, 13,-34,-38,-15,-43,-12, 29, 17, 14,-37,-46,-35,-27,-32,-14, 33,-54,-39;
/M: SY='T'; M=-10,-45, -1, 53,-48,-14,-36,-32,-10,-42, 13,-26,-35,-10,-34,  5, 66,-29,-58,-43;
/M: SY='G'; M=-22,-51,-36, 10,-48, 73,-42,-19,  0,  1,-38,-20,-43,-14,-25, -7,-39,-44,-50,-46;
/M: SY='K'; M=  6,-49,-29, 28,-53, -8,-34,-38, 44,-48,-40,-10, -7, 37, 16, 22, -2,-16,-52,-42;
/M: SY='D'; M=-27,-52, 64, 30,-47,-34, -2,-42,-30, 13,-37,-25, 24, 11,-21, 14, -4,-42,-60,-41;
/M: SY='Y'; M=  4,-53,-42,-28,  8,-15,  4,-31, 12,-28,-32,-25, -1, 26, -7,-23,-11,-12, 65, 74;
/M: SY='K'; M=  6,-50, -8, -2, 10,-43,-38,-35, 61,-17,-37,-32, 46,-15,-18, -9, -6,-23, -9,-37;
/M: SY='P'; M= 38,-50,-41,-19,-18,-24,-43,-21, 26,-43,-37,-39, 73,-25,-19,-19,-20,  6,-51,-28;
/M: SY='P'; M= -3,-51, 28,-13,-32, 44,-43,-15,-28,-10,-37, -9, 53,-39,-46,-16,-34, 12,-55,-46;
/M: SY='C'; M= 22, 38,  8,-31,-49, 12,-30,-42, 17,-29,-24,  8,  4, 10,-34, 29, 12,-11,-57,-44;
/M: SY='P'; M= 28,  3,-39,-35,-46, -8,-42, -1,  2,-13,-34, -7, 49, -1,-21, 18, 23,-11,-54,-44;
/M: SY='P'; M= 17,-50,-39,-32,  8,-25,-41,-40, 23,-45,-39,-20, 76,-18,-10, 10,  7, -9,-50,-41;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 37 in 28 different sequences
Number of true positive hits 37 in 28 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] V_Lesaux
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Feature key [info] DOMAIN
Feature description [info] WHEP-TRS
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
28 sequences

GARS_CAEEL  (Q10039    ), GARS_HUMAN  (P41250    ), GARS_MOUSE  (Q9CZD3    ), 
GARS_PONAB  (Q5RBL1    ), SYEP_CRIGR  (Q7SIA2    ), SYEP_DROME  (P28668    ), 
SYEP_HUMAN  (P07814    ), SYEP_MOUSE  (Q8CGC7    ), SYGM1_ARATH (O23627    ), 
SYG_BOMMO   (Q04451    ), SYHC_BOVIN  (Q2KI84    ), SYHC_HUMAN  (P12081    ), 
SYHC_MESAU  (P07178    ), SYHC_MOUSE  (Q61035    ), SYHC_PONAB  (Q5R4R2    ), 
SYH_SCHPO   (O43011    ), SYMC_BOVIN  (Q2T9L8    ), SYMC_HUMAN  (P56192    ), 
SYMC_MOUSE  (Q68FL6    ), SYMC_XENLA  (Q6PF21    ), SYNC1_ARATH (Q9SW96    ), 
SYNC3_ARATH (Q9SSK1    ), SYWC_BOVIN  (P17248    ), SYWC_HUMAN  (P23381    ), 
SYWC_MOUSE  (P32921    ), SYWC_PONAB  (Q5R4J1    ), SYWC_RABIT  (P23612    ), 
SYWC_RAT    (Q6P7B0    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

GARS_RAT    (Q5I0G4    )

		
PDB
[Detailed view]
8 PDB

1D2D; 1FYJ; 1R1B; 1R6T; 1X59; 2DJV; 2LW7; 5E6M

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