Entry: PS51423

General information about the entry
Entry name MIRO
Accession number PS51423
Entry type MATRIX
Date DEC-2008 (CREATED); DEC-2008 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC51417
Associated ProRule PRU0075
Name and characterization of the entry
DescriptionMiro domain profilee.
Matrix / Profile 
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=150;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=145;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-4.1808591; R2=0.0049793; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=2547; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=2146; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-40; I=-40; I0=-15; B1=*; E1=*; MI=-210; MD=-210; IM=-210; DM=-210;

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-210; BD=-210;
/M: SY='H'; M=  -3, -61,   7,   8, -59,  15,  22, -47,  17, -46, -24,  -1, -15,  13,  19,   5,  10, -37, -57, -21;
/M: SY='Q'; M=  -1, -60,  -1,   7, -58, -14,  -9, -46,  20, -46, -24,  -2, -22,  58,  14,  -2,  -8,  -3, -57, -39;
/M: SY='T'; M= -14, -47,  -8,  10, -28, -50, -12, -16,  -2, -31, -11,  15, -24,   6, -14,  13,  44,   7, -46,  -6;
/M: SY='Q'; M= -11, -66,  40,  12, -65, -29,  -9, -54,   6, -52,  -7,   0, -40,  58,  -1,   7,  31, -42, -61, -43;
/M: SY='R'; M= -32, -72, -32, -10, -75, -59, -11, -60,  45, -27, -36,  -1, -51,  10,  83, -15, -22, -52, -62, -50;
/M: SY='N'; M=   1, -42,   8,  20, -68, -48,  -9, -57,  40, -54, -31,  50, -41,  13,   9,  28,   8, -45, -63, -44;
/M: SY='V'; M= -12, -29,  25,   3, -42, -52, -15, -27,  -5, -24, -12,   4, -45,   2,  -3, -10,  11,  57, -47, -33;
/M: SY='F'; M= -27, -35, -79, -61,  57, -76, -40,  28, -56,  22,  18, -53, -65, -41, -55, -37, -19,  52, -33,   8;
/M: SY='R'; M= -21, -60, -22,  -3, -56, -54, -12, -43,  19,  17,   6,  24, -46,  25,  63, -13, -13, -35, -55, -40;
/M: SY='C'; M= -18,  97, -67, -51, -27, -22, -38,  53, -47, -13,   0, -43, -57, -35, -48, -25, -13,  23, -41, -30;
/M: SY='V'; M= -15,  12, -42, -24,  21, -57,  27,  -8,  13,  16,   3,   1, -49, -13, -17, -17,  -8,  31, -33,  25;
/M: SY='V'; M= -41, -45, -97, -81, -31, -99, -71,  47, -78,  33,  15, -76, -85, -64, -79, -63, -34,  74, -62, -53;
/M: SY='C'; M= -20,  57, -84, -67, -27, -80, -51,  45, -63,  35,   4, -59, -70, -49, -62, -43, -22,  53, -47, -36;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='D'; M=  32, -68,  49,  25, -67, -47, -10, -56,  16, -54, -12,  -1,   8,  12, -10,  13, -10, -35, -63, -44;
/M: SY='K'; M=   7, -70,   6,  33, -70, -38,   7, -59,  34, -56, -32,   7,  20,  22,  32,   9,   1, -47, -64, -45;
/M: SY='G'; M= -18, -67,  17,   8, -66,  53, -11, -54,  11, -53,  -6,  24, -42,  24,   1,   6, -11, -44, -63, -45;
/M: SY='V'; M=  17,  47, -52, -37, -35, -46, -32, -14, -35, -25,  -8, -30, -47, -24, -40,  37,  23,  51, -45, -34;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/I:         I=-7; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='T'; M= -12, -47, -18,   5, -62, -41, -25, -48, -14, -52, -31, -13, -43,  -7, -25,  66,  66, -36, -65, -50;
/M: SY='S'; M=  28, -42, -11, -14, -61,   1, -26, -48, -17, -51, -30, -15, -41,  -8, -28,  73,   1, -10, -64, -50;
/M: SY='L'; M= -30, -39, -77, -59,  43, -78, -42,  17, -55,  61,  27, -54, -67, -40, -55, -16, -22,  10, -37, -26;
/M: SY='I'; M= -35,  11, -91, -74, -23, -88, -57,  63, -70,  52,  34, -67, -76, -54, -68, -51, -28,  24, -49, -41;
/M: SY='Q'; M=   0, -64,  12,  25, -62, -49, -10, -51,   5, -29,  35,  11, -41,  47,  33,  10,  16, -22, -60, -42;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='S'; M=  43,   4, -35, -21, -59, -14, -30, -46, -22, -50, -29,  15, -41, -13, -32,  68,  -6, -21, -63, -50;
/M: SY='F'; M= -47, -52, -96, -79,  72, -97, -56,   6, -75,  60,  31, -73, -81, -55, -72, -60, -39,   7, -40, -27;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='V'; M=  -6, -35, -65, -47, -23, -71, -38,  29, -44,  47,   6, -44, -62,  -2, -47, -32,  -7,  49, -40, -30;
/M: SY='K'; M= -13, -68,  -7,  17, -67,  32,   6, -56,  37, -54, -30,  32, -13,  26,  -9,  14, -10, -21, -63, -44;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='R'; M= -12, -73,  30,  43, -74, -13,  15, -64,  12, -60, -35,  26, -41,  20,  52,  -6, -11, -51, -67, -47;
/I:         I=-10; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='E'; M=  -5, -69,  10,  44, -69,  -2,  -9, -58,   6, -45, -31,  24,  12,  31,   0,  24,  -1, -27, -64, -45;
/M: SY='F'; M= -17, -27, -66, -48,  63, -63, -27,  10, -43,  22,  45, -18, -54, -29, -42, -24,   9,   2,  28,  29;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='Q'; M=  -5, -40,   3,  13, -38, -33,  19, -29,   4, -21, -14,  -1, -28,  22,   0,  14,   1,  -8, -38, -15; D=-8;
/I:         I=-8; DM=-41;
/M: SY='Q'; M=   6, -46,  10,  16, -45, -15,   2, -37,  18, -36, -20,   8, -28,  22,  -6,   1,   4, -29, -43, -30; D=-8;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='Q'; M=   1, -38,   7,   3, -35, -22,  -6, -10,   9,  -8, -12,  -2, -28,  23,   9,  -4,   6, -20, -36, -25; D=-8;
/I:         I=-8; DM=-41;
/M: SY='Y'; M=   0,  -2,  -1,  -1,  -1,  -2,  -1,   1,  -1,  -1,   0,  -1,  -2,   0,   0,  -1,   0,   0,  -2,   2; D=-8;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='P'; M= -12, -56,  -7,  10, -52, -50, -12,  -7,  12, -41, -19,  18,  61,   8,  11,   4,  -1,   9, -53, -37; D=-8;
/I:         I=-8; DM=-41;
/M: SY='E'; M= -12, -71,  24,  47, -70, -25,  -9, -60,  11, -57, -33,  16,   4,  13,  16,  -1,  44, -48, -65, -46;
/M: SY='H'; M=   1, -55, -16,  30, -16, -50,  37,  16,  22, -27, -18,  20, -24,  25, -13,   0,   7, -29, -10,  -6;
/I:         I=-3; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='Q'; M= -12, -66, -10,  32, -45, -49,  -9, -16,  37, -42, -28,  -2,  34,  39,  23,   8,   2, -42, -61, -43;
/M: SY='P'; M= -16, -36, -40, -23, -29, -56, -23,  40, -22, -18,  14, -24,  55, -12, -29,  19,   7,  24, -39, -27;
/I:         I=-2; MD=-12;
/M: SY='T'; M= -15, -46, -22,  -5, -23, -40, -15, -16,   4,  -6,   8,  27, -44,   2,  17,   3,  49,  -1, -45,   3; D=-2;
/I:         I=-2; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='I'; M= -15, -32, -44, -26,   2, -57,  16,  52, -24,  -4,   4, -10, -49,  -2, -21,   7,  12,   1, -32,  38; D=-2;
/I:         I=-2; DM=-12;
/M: SY='P'; M=  34,  13, -41, -26, -42, -43, -28, -25, -25, -33, -14, -23,  64, -15, -33,   6,   6,  28, -50, -38; D=-2;
/I:         I=-2; DM=-12;
/M: SY='I'; M=   7, -15, -15,  -8, -11, -22,  -8,  16,  -1,  -8,   0,  -9,   3,  -4,  -1,  -2,  -3,  15, -15, -10; D=-2;
/I:         I=-2; DM=-12;
/M: SY='N'; M= -25, -82,  55,  22, -81, -30, -15, -72,   3, -68, -46,  78, -44,   6, -22,   8,  -2, -59, -77, -55; D=-2;
/I:         I=-2; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='T'; M= -15, -40, -16, -12,  11, -54, -17,   1, -12, -23,  -5,  -6, -23,  -3,   0,  31,  44,  24, -40, -27; D=-2;
/I:         I=-2; DM=-12;
/M: SY='V'; M=  -8, -37, -17, -18, -33, -24, -21,  -7, -17, -14,  -5, -20, -47,  -8, -26,  14,  38,  54, -41, -29; D=-2;
/I:         I=-2; DM=-12;
/M: SY='E'; M= -12, -66,  -9,  45, -64, -48,  -9, -53,  12, -40, -28,  -2,  34,  35,  14,  22,   7, -42, -61,  -3; D=-2;
/I:         I=-2; DM=-12;
/M: SY='V'; M= -15, -43, -26,  33, -14, -53, -16, -12,  -9,   3,  22,  -2,  -9,  10, -20,  14,  -8,  35, -42, -28; D=-2;
/I:         I=-2; DM=-12;
/M: SY='Q'; M=  -2, -64,   2,  24, -63, -27,  -8, -52,  23, -50, -27,  18,  19,  29,   5,   1,   6, -41, -60,  17; D=-2;
/I:         I=-2; DM=-12;
/M: SY='G'; M= -17, -59,   8,  20, -57,  45, -12, -45,  -1, -46, -25,   8, -41,   7, -15,   3,  -3, -36, -58,   2; D=-2;
/I:         I=-2; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='Q'; M=  -8, -59,   5,  20, -58,   7,  -9, -47,   4, -47, -25,   0, -39,  58, -10,  -6,   3, -22, -57, -40; D=-2;
/I:         I=-2; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='E'; M= -12, -73,  11,  48, -73, -47,  -9, -63,  39, -59, -34,  31,  10,  31,   7,   8, -10, -50, -66, -47; D=-2;
/I:         I=-2; DM=-12;
/M: SY='K'; M= -18, -58, -17,   5, -32, -51, -11, -31,  53, -32, -21,  -7, -44,  50,  11,  -9, -10,  26, -54, -39; D=-2;
/I:         I=-2; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='Y'; M= -16, -45, -24,  -7, -38, -53,  15,  -9,  -7, -29, -10,  15,  16,   1, -18,   7,  19, -12, -44,  78;
/M: SY='T'; M= -27, -43, -59, -43, -26, -69, -39,   2, -37,  55,  18, -42, -62, -29, -42, -31,  60,   1, -47, -36;
/M: SY='I'; M= -16, -32, -45, -28, -23, -58,  29,  48, -16,   6,   3, -28, -50, -15, -31,  11,  18,  34, -33, -22;
/I:         I=-11; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='L'; M= -49, -52,-103, -86, -20,-104, -72,  57, -82,  66,  34, -82, -87, -63, -80, -68, -41,  18, -56, -52;
/M: SY='V'; M= -16,  26,  -7,  20, -23, -53,  17,   2,  -6, -29, -10, -12, -45,  34,  14,   0,  -8,  39, -45, -31;
/I:         I=-10; MI=0; MD=-52; IM=0; DM=-52;
/M: SY='D'; M= -36, -98,  82,  73, -96, -44, -21, -89, -19, -84, -64,   4, -47,  -2, -39, -20, -32, -75, -92, -67;
/I:         I=-9; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='T'; M= -19, -29, -65, -47,  25, -65, -31,  26, -43,  22,   9, -41, -56, -29, -43, -26,  44,  37, -31,  22;
/M: SY='S'; M=  -8, -70,  36,   9, -70,  28, -12, -59,   5, -46, -34,  12, -42,  25, -14,  49, -13, -47, -67, -47;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='E'; M=   1, -67,  29,  48, -38, -39,  -9, -27,   6, -29, -29,  16, -41,  24,   6,  30,  -9, -44, -62, -43;
/M: SY='S'; M=  -4, -61,  -2,   5, -58, -38,  17, -46,  19, -12, -24,   8, -42,  31,   8,  45,  14,  -7, -57, -40;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='E'; M= -22, -74,  21,  65, -73, -41, -11, -63,   1, -60, -39,  14, -40,  28,  -4,  -1, -16, -51, -69, -49; D=-8;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='D'; M=  23, -69,  43,  37, -68, -45,   5, -58,   3, -56, -33,   6, -25,  11, -13,  10,  12, -46, -65, -46; D=-8;
/I:         I=-8; DM=-41;
/M: SY='I'; M=  -4, -45,   5,  16, -39, -51, -13,  27,  -4,  -3,  16, -10, -26,   4,  20,  -9,  -7,  -3, -44, -30; D=-8;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='E'; M=  -3, -61,  28,  41, -58, -49, -11, -32,   2,  27, -24,  12, -24,   9, -12,  -1,  12, -36, -58, -40;
/M: SY='E'; M=  14, -54, -17,  32,   4, -40,  16, -36,   0, -10, -17,  20, -11,  23,   6,  -1,  10, -23,  19, -13;
/M: SY='L'; M= -11, -47,  -5,   4, -41, -53, -16,  -9,  -7,  46, -11,  45, -46,   0, -19, -12,   4, -19, -46, -32;
/M: SY='Q'; M=  11, -65,  -2,  12, -64, -17,  24, -37,  22, -40, -28,  -2,  -7,  55,  12,   7,  21, -30, -61, -30;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='S'; M=  22, -68,  -3,  27, -67, -38,  11, -56,  34, -45, -30,  -1, -10,  24,  11,  36,  -1, -44, -62, -44;
/M: SY='E'; M=   8, -69,  -9,  57, -68, -22,  -9, -57,  30, -30, -31,  -2, -42,  26,  19,  13, -10, -45, -63, -45;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='I'; M= -17, -44,  24,  22, -36, -56, -19,  37, -11,  33,   8, -17, -48,  -3, -22, -14, -10,  -7, -44, -31;
/M: SY='K'; M=  15, -66,  27,  19, -65, -48,  -9, -31,  30, -42, -12,  10, -41,  17,  25,  14,  16, -16, -61, -43;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='Q'; M=  13, -67, -10,  22, -66, -48,  -9, -43,  34, -44,  -2,  26, -23,  47,  15,  19,   8, -44, -62, -43;
/I:         I=-3; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='C'; M=  62, 102, -62, -53, -57, -34, -48, -36, -50, -48, -30, -34, -42, -38, -52,  11,  -6, -24, -65, -56;
/M: SY='D'; M= -31, -89,  88,  14, -86, -45,  23, -80, -12, -76, -54,  57, -46,   2, -30, -10, -26, -66, -83, -59;
/M: SY='V'; M= -41, -46, -95, -80, -38, -97, -74,  38, -76,   4,  -4, -76, -86, -66, -79, -62, -35,  88, -69, -57;
/M: SY='I'; M=  18, -40, -84, -68, -35, -87, -59,  73, -65,  10,  -2, -63, -76, -53, -67, -50, -27,  49, -58, -47;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='C'; M=  -2, 105, -63, -45, -17, -62, -29,   9, -40,   3,   7, -39, -55, -28, -41, -24, -10,  16,  67, -18;
/M: SY='L'; M= -30, -38, -79, -61,  18, -78, -40,  23, -56,  58,  14, -54, -67, -41, -56, -39, -22,  21, -33,  40;
/M: SY='V'; M=   0, -12, -68, -50, -27, -71, -40,  14, -47,   8,  52, -46, -62, -35, -50, -32,  11,  69, -42, -31;
/M: SY='Y'; M= -67, -69, -84, -77,  51, -95,  19, -50, -72, -39, -35, -54, -84, -50, -69, -59, -59, -51,  15, 122;
/M: SY='D'; M=   7, -19,  78,   1, -69, -43, -18, -57,  -7, -58, -35,  -6, -42,   2, -21,  44, -12, -44, -68, -51;
/I:         I=-12; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='S'; M= -11, -35, -38, -23, -35, -24, -25,  14, -22, -24,  -7, -23, -46, -13, -30,  52,  -7,  40, -44, -32; D=-12;
/I:         I=-12; DM=-61;
/M: SY='S'; M=  -3, -48,   5,  -3, -64, -38, -21, -52, -12, -54, -33,   8, -40,  -3, -24,  73,  19, -39, -65, -50; D=-12;
/I:         I=-12; DM=-61;
/M: SY='D'; M= -23, -93,  90,  24, -91, -44, -19, -83,  -9, -79, -58,  55, -46,   7, -34, -18, -28, -70, -87, -63;
/M: SY='P'; M= -18, -67,  11,  20, -65, -48,  53, -54,  16, -34, -30,   8,  67,  11, -10,   0,   8, -43, -62, -44;
/M: SY='D'; M= -13, -70,  42,  33, -70, -38,   5, -60,  24, -56, -32,  32, -41,  13,  16,  11,   3, -47, -65,  28;
/I:         I=-7; MI=0; MD=-38; IM=0; DM=-38;
/M: SY='S'; M=  -5, -37, -36, -30, -70, -34, -40, -56, -33, -62, -42, -24, -41, -24, -40,  88,  44, -39, -74, -62;
/M: SY='F'; M= -25,  -4, -72, -55,  80, -71, -27,  17, -50,   3,   6, -46, -61, -35, -49, -32, -17,  13, -19,  54;
/M: SY='E'; M=  14, -73,  36,  57, -72, -47, -11, -62,   2, -59, -36,  16, -42,  18, -13,  33, -13, -29, -68, -48;
/M: SY='Y'; M= -17, -51, -22,  -4,   4, -39,  33, -31,  18, -21, -14, -11, -45,  11,  46, -11, -10, -25, -46,  62;
/M: SY='I'; M= -32,  69, -91, -74, -32, -87, -59,  70, -70,   5,  -1, -66, -76, -57, -70, -50, -26,  52, -54, -44;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='A'; M=  36, -43, -14,   4, -37, -53, -17,  -4,  -9,  11,  -8, -14, -19,  -1, -20,  21,  15,   8, -43, -30;
/M: SY='H'; M= -11, -62,  -5,  19,   9, -36,  28, -48,  26, -47, -25,  27, -41,  16,  20,  20,  16, -38, -58,  16;
/M: SY='W'; M= -28, -37, -77, -59, -14, -76, -39,  35, -54,  37,  12, -52, -65, -39, -53, -37, -21,  27, 115, -21;
/M: SY='Y'; M= -18, -31, -54, -36,  -3, -62, -26,  20, -33,  30,  49, -34, -53, -22,  24, -22, -10,   3, -31,  56;
/M: SY='P'; M= -11, -64,  -4,  11, -62, -49, -10, -15,  40, -50,   2,  14,  56,  39,   0,  -2,  -2, -40, -60, -42;
/M: SY='Q'; M= -17, -56, -18,   0, -51, -51,  13, -38,  40,  13,  20,   1, -44,  45,  16,  -9,  -3, -31, -53,  25;
/M: SY='Y'; M= -23, -36, -56, -39,  52, -65,  56,  18, -36, -16,  -1, -19, -57, -24, -40, -26, -15,  10, -15,  73;
/M: SY='R'; M= -16, -57,  -7,   7,   6, -36, -12, -40,   1, -41, -20,  22,  24,  14,  50,   1,  -9, -32, -54,  39;
/M: SY='M'; M=   0, -53,  -3,   9, -48, -23,  32, -25,  -1, -19,  54,   2, -43,  27,  -5,  34,  -8, -19, -51,   9;
/I:         I=-5; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='D'; M= -16, -61,  36,  20, -58,  28, -10, -46,   4,   7,  -6,   3, -26,  10,   7,  -6,  -9, -37, -57,  -6; D=-5;
/I:         I=-5; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='S'; M= -12, -60,  20,  12, -57, -11,  16, -22,  15, -19, -23,  -4, -29,  28, -11,  32,   8,  15, -57, -40;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='N'; M= -13, -72,   0,  35, -72, -35,  11, -62,  35, -58, -34,  52, -41,  41,  27,   2,  -2, -49, -66, -46;
/I:         I=-4; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='I'; M= -22, -33, -63, -45, -24, -69, -35,  48, -21,  31,  19, -42, -60, -30, -45, -30,  38,  35, -38, -28;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M:
/M: SY='C'; M=  -5,  75, -67, -49, -22, -65, -34,  42, -45,  -2,  14, -42, -57, -32, -46,   9, -12,  44, -35, -24;
/M: SY='V'; M= -41, -45,-100, -83, -31, -99, -71,  62, -80,  29,  29, -78, -85, -66, -80, -63, -34,  66, -61, -53;
/M: SY='F'; M= -33, -40, -85, -67,  58, -82, -45,  26, -62,  53,  38, -59, -70, -45, -60, -44, -25,   4, -35,  11;
/M: SY='V'; M= -14,  64, -81, -64, -31, -77, -50,  44, -60,  -5,  -1, -57, -69, -48, -61, -40,  -3,  68, -49, -38;
/M: SY='A'; M=  52, -16, -19,   4, -53,  29, -17, -40,   7, -42, -21, -10, -43,   2,  -2,   8,  -9, -31, -55, -40;
/M: SY='N'; M=   0, -14, -23,  -7, -47, -48, -17, -32,  -7,   6, -16,  68, -44,   0, -19,  20,  36, -25, -51, -37;
/M:
/M: SY='S'; M=  39,  34, -42, -25, -12, -56, -23,  11, -24, -17,   0, -25, -49, -14, -31,  46,  -8,   7, -36,  -8;
/M: SY='D'; M= -39, -98, 103,  32, -97, -44, -24, -90, -23, -86, -68,   3, -49,  -5, -44, -23, -35, -76, -93, -69;
/M: SY='L'; M= -16, -49,  11,  -4, -43, -28, -14, -30,   1,  47,  16,   0, -45,  18,  10,  -4,  -9, -23, -48, -33;
/I:         I=-2; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='D'; M= -17, -63,  53,  22, -62, -27,  20, -52,   2, -50, -30,   4,  11,  10, -13,  -6, -11, -28, -59, -41; D=-2;
/I:         I=-2; DM=-10;
/M: SY='E'; M=   0,  -1,   0,   1,  -1,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-2;
/I:         I=-2; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='Q'; M=   0,  -2,  -1,   0,  -2,   0,  -1,  -2,   0,  -2,  -1,   0,  -2,   2,   0,   0,   1,   1,  -2,  -2; D=-2;
/I:         I=-2; DM=-10;
/M: SY='Q'; M= -15, -59,   9,   7, -57, -46,  -8, -45,  23, -37, -23,   4, -39,  52,  14,  -5,   9,  -7, -55, -38; D=-2;
/I:         I=-2; DM=-10;
/M: SY='Q'; M=   1, -54,  -5,   2, -60, -41, -14, -48,   3, -49, -29,  -4, -19,  83,  -6,  -2, -12, -38, -59, -44; D=-2;
/I:         I=-2; DM=-10;
/M: SY='R'; M= -15, -59,   7,  14, -56, -46,   8, -45,   9, -34, -23,  -2,  -6,  20,  50,  -5,  -8, -26, -54, -20; D=-2;
/I:         I=-2; DM=-10;
/M: SY='H'; M=  -4,  29, -35, -18,  -9, -53,  35,  -8, -17, -14,   3, -20,   1,  -7, -24,   0,  -5,  -4,  31,  34; D=-2;
/I:         I=-2; DM=-10;
/M: SY='E'; M= -16, -64,  15,  40, -62,   5,   4, -51,   9, -28, -28,   8, -13,  12, -10,   9,  -9, -41, -60, -41; D=-2;
/I:         I=-2; DM=-10;
/M: SY='M'; M= -16, -29, -49, -32,  -7, -59,   5,  23, -29,  21,  37, -31, -30, -18, -34, -20,  -8,  30, -30, -19; D=-2;
/I:         I=-2; DM=-10;
/M: SY='Q'; M= -10, -39,  -3,   3, -43, -29,  -9, -35,   1, -35, -21,  -2,  -1,  49,  -6,  25,  -7, -28, -43, -31; D=-2;
/I:         I=-2; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='V'; M=  -6, -36, -27,  -3,  -6, -40, -14,   3,  -8, -12,   0, -14, -43,  11,   7, -10,   9,  11, -36,  -9;
/M: SY='E'; M=   4, -24,  11,  16, -48, -26,  -9, -26,   3, -37,  -5,  -3,  -4,  10, -10,  13,   2, -19, -50, -34;
/M: SY='N'; M= -15, -60,  12,  18, -57,  -5,  -8, -45,  14, -45, -24,  28, -39,  17, -10,   2,  -1, -36, -57,   8;
/M: SY='S'; M=  -1,  -2,   0,   0,  -1,  -1,   0,  -1,   0,  -1,   0,   1,  -2,   0,   0,   1,   0,  -1,   0,   0;
/M: SY='T'; M= -11, -19, -17,  -1, -42, -46, -12, -28,  11, -25, -12,  15, -40,  16, -11,  20,  25,  -6, -46, -32;
/I:         I=-10; MI=0; MD=-54; IM=0; DM=-54;
/M: SY='M'; M=  -3, -47,   4,   8, -44, -31, -10, -30,   1, -33,  42,  -5, -23,   8,  -5,  15,  12, -23, -47, -32;
/M: SY='N'; M=  -8, -62,  10,  27, -59, -44,  -8, -48,  16, -27, -25,  31, -26,  13,   2,   5,  -4, -38, -58, -40;
/M: SY='Q'; M=   5, -50,  -3,   8, -45, -47,   9, -12,   3, -20, -13,   3, -40,  31, -10,   8,   8, -19, -48, -32;
/M: SY='V'; M=  -6, -37, -15,  -8, -31, -36, -14,   7,   4,  -6,  11,  -4, -43,   1, -18,  -2,   4,  14, -38, -25;
/M: SY='L'; M=  -8, -34, -32,  -6, -14, -53, -18,  12, -14,  15,   2, -18, -11,  -5, -22,   1,   0,   6, -35, -23;
/M: SY='S'; M= -11, -18, -10, -14, -18, -12, -13, -13, -15, -14, -13, -13, -16, -11, -14, -10, -11, -10, -15, -13;
/M: SY='S'; M= -11, -18, -11, -14, -19, -13, -13, -13, -15, -15, -13, -13, -16, -12, -14, -10, -11, -10, -15, -13;
/M: SY='S'; M= -11, -18, -11, -14, -19, -13, -13, -13, -15, -15, -13, -13, -16, -12, -14, -10, -11, -10, -15, -13;
/M: SY='S'; M= -11, -18, -11, -14, -19, -13, -13, -13, -15, -15, -13, -13, -16, -12, -14, -10, -11, -10, -15, -13;
/M: SY='S'; M= -11, -18, -10, -14, -18, -12, -13, -13, -15, -14, -13, -13, -16, -11, -14, -10, -11, -10, -15, -13;
/M: SY='S'; M=  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,   0,  -1,  -1,  -1,  -1;
/M: SY='S'; M= -11, -18, -11, -14, -19, -13, -13, -13, -15, -15, -13, -13, -16, -12, -14, -10, -11, -10, -15, -13;
/M: SY='S'; M= -11, -18, -11, -14, -19, -13, -13, -13, -15, -15, -13, -13, -16, -12, -14, -10, -11, -10, -15, -13;
/M: SY='S';
/M: SY='S'; M= -11, -18, -11, -14, -19, -13, -13, -13, -15, -15, -13, -13, -16, -12, -14, -10, -11, -10, -15, -13;
/I:         E1=0; IE=-210; DE=-210;
Post-processing
COMPETES_HIT_WITH: PS51417; PS51418; PS51419; PS51420; PS51421; PS51422; PS51424;
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 65 hits in 33 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 65 hits in 33 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 1
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 98.48 %
Comments
  • MATRIX_TYPE: protein_domain
  • Scaling database: UniProtKB/Swiss-Prot: reversed
  • Matrix author: N_Hulo, L_Cerutti
  • Taxonomic range: Archaea, Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 2
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
GEM1_ASHGO  (Q758X6), GEM1_ASPFU  (Q4WN24), GEM1_ASPOR  (Q2UM43), 
GEM1_CANAL  (Q5ABR2), GEM1_CANGA  (Q6FIR8), GEM1_CRYNB  (P0CO79), 
GEM1_CRYNJ  (P0CO78), GEM1_EMENI  (Q5B5L3), GEM1_GIBZE  (Q4I2W2), 
GEM1_KLULA  (Q6CY37), GEM1_NEUCR  (Q7RZA2), GEM1_SCHPO  (O59781), 
GEM1_USTMA  (Q4PB75), GEM1_YARLI  (Q6C2J1), GEM1_YEAST  (P39722), 
GEMA_DICDI  (Q55G45), MIRO1_BOVIN (Q2HJF8), MIRO1_CHICK (Q5ZM73), 
MIRO1_DANRE (Q6NVC5), MIRO1_HUMAN (Q8IXI2), MIRO1_MOUSE (Q8BG51), 
MIRO2_BOVIN (Q5E9M9), MIRO2_CHICK (Q5ZM83), MIRO2_DANRE (Q32LU1), 
MIRO2_HUMAN (Q8IXI1), MIRO2_MOUSE (Q8JZN7), MIRO2_PIG   (Q864R5), 
MIRO2_RAT   (Q7TSA0), MIRO2_XENTR (Q6DIS1), MIRO_CAEBR  (Q623S8), 
MIRO_CAEEL  (Q94263), MIRO_DROME  (Q8IMX7), MIRO_DROPS  (Q298L5)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
Y765_METTH  (O26859)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

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