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Entry: PS51446

General information about the entry

Entry name [info] PACIFASTIN
Accession [info] PS51446
Entry type [info] MATRIX
Date [info] 01-APR-2009 CREATED; 01-OCT-2013 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51446
Associated ProRule [info] PRU00776

Name and characterization of the entry

Description [info] Pacifastin domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=35;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=35;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.1693327; R2=0.0095010; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=562; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=414; N_SCORE=7.1; MODE=1; TEXT='R?';
/DEFAULT: M0=-12; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='G'; M=  1, -6,-24, -3, -1,-26,  5,-16,-21, -7,-26,-18, -8,-10, -6,-13,  3, -5,-14,-32,-23, -2;
/M:         M= -4,-10,-18,-11, -7,-16,-15,-15, -8, -8,-11, -7, -9,-18, -6,-12, -2, -3, -5,-27,-16, -7;
/M: SY='E'; M= -5, -6,-26, -5,  8,-21,-13, -2,-19, -4,-21,-12, -5, -9,  8, -8, -2, -9,-15,-26,-12,  8;
/M: SY='C'; M=  0,-30, 90,-40,-40,-20,-30,-30,-10,-30,-10,-20,-30,-30,-30,-40,-10,-10,-10,-20,-20,-40;
/M: SY='T'; M= -3, -6,-20, -5,  3,-20,-14, -8,-18, -4,-19,-14, -2,-12, -3, -7,  4, 20,-11,-27,-14,  1;
/M: SY='P'; M=-10,-11,-31,-11, -5,-30, -6,-15,-30,-10,-31,-26,-11, 36, -9,-17, -6,-12,-23,-34,-24, -6;
/M: SY='G'; M= -5,  1,-30,  1,-12,-30, 37,-14,-36,-15,-38,-27,  3,-19,-14,-16,  2,-12,-28,-34,-28,-13;
/M: SY='S'; M=  3, -3,-21,  0, 10,-26, -6,-11,-23, -2,-28,-20, -2,  0,  1, -9, 14,  3,-20,-31,-22,  7;
/M: SY='T'; M= -3, -3,-21, -6, -3,-24,-14,-10,-18,  2,-21,-16,  5,-14, -1,  7, 10, 14,-14,-32,-20, -3;
/I:         I=-13; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='W'; M=-22,-30,-21,-38,-23, 18,-29,-13,-12,-17,-13,-12,-29,-33,-18,-22,-21,-22,-17, 42, 20,-22;
/M: SY='K'; M=-10, -9,-29,-16,  0,-20,-22, -7,-24, 22,-20,-13, -5,-10,  5, 17, -6, -7,-18,-25,-13,  1;
/M: SY='E'; M= -9, -2,-25,  0,  6,-18,-20, -7,-15,  1,-18,-12, -5,-17,  2, -7, -4, -9,-13,-26, -9,  4;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='D'; M=-12, 12,-35, 20, 10,-30,  6, -8,-32, -5,-35,-25,  0,-18,  0,-13, -1,-14,-27,-34,-21,  5;
/M: SY='C'; M=  0,-30, 90,-40,-40,-20,-30,-30,-10,-30,-10,-20,-30,-30,-30,-40,-10,-10,-10,-20,-20,-40;
/M: SY='N'; M=-19, 28,-30,  9,  1,-30,-11,  9,-30,  4,-39,-20, 56,-19,  1,  1,  9, -1,-29,-39,-20,  1;
/M: SY='W'; M=-13,-15,-20,-16,-12, -8,-22,-15,-14,-15,-15,-10,-14,-24, -8,-15, -7,  0,-15,  8, -6,-13;
/M: SY='C'; M=  0,-30, 90,-40,-40,-20,-30,-30,-10,-30,-10,-20,-30,-30,-30,-40,-10,-10,-10,-20,-20,-40;
/M: SY='T'; M= -5,-12,-20,-16, -8,-10,-19,-11,-13, -2,-14,-10, -5,-17, -3,  1,  3, 10,-10,-23,-11, -7;
/M: SY='C'; M=  0,-30, 90,-40,-40,-20,-30,-30,-10,-30,-10,-20,-30,-30,-30,-40,-10,-10,-10,-20,-20,-40;
/M: SY='T'; M=  1, -7,-17, -9, -7,-21,-13,-15,-10, -5,-16,-11, -3,-15, -6, -9,  5,  6, -5,-31,-19, -6;
/M: SY='N'; M= -7, 11,-26,  5,  4,-28,-12, -1,-26,  5,-32,-20, 18, -9,  1, -3,  7, -1,-22,-36,-20,  3;
/M: SY='G'; M= -6,  0,-27, -1,-10,-27, 21,-11,-29,-15,-31,-22,  1,-19,-12,-15,  0, -8,-23,-33,-24,-12;
/I:         I=-13; MD=-27;
/M: SY='G'; M= -1, -8,-18, -8,-13,-17, 31,-13,-21,-13,-20,-16, -8,-13,-13,-13, -2,-12,-16,-18,-18,-13; D=-13;
/I:         I=-13; MI=0; MD=-27; IM=0; DM=-27;
/M:         M= -3,-18,-15,-21,-14,-10,-23,-13,  0,-10, -4, -5,-14,-20,-11, -8, -3,  0,  0,-24,-11,-14;
/M: SY='G'; M=  9,-19,-18,-21,-15,-19, 11,-16,-22,-14,-25,-17,-17,-12,-13,-12, -3,-12,-16,-16,-15,-15;
/M: SY='A'; M=  5,-17,-11,-18,-13,-13,-13,-18, -3,-13, -9, -3,-13,-18, -8,-16,  4,  0, -2,-19,-15,-12;
/I:         I=-15; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='C'; M=  0,-30, 90,-40,-40,-20,-30,-30,-10,-30,-10,-20,-30,-30,-30,-40,-10,-10,-10,-20,-20,-40;
/M: SY='T'; M=  1, -9,-10, -9, -9,-20,-19,-19,-11, -9,-11,-11,  1,-10, -9,-10, 12, 48, -1,-30,-20, -9;
/M: SY='R'; M=-11,-20,-24,-22, -9,-14,-27,-13, -6, -4,  2,  3,-15,-22, -3,  7,-14, -3, -6,-24,-11, -9;
/M: SY='K'; M= -8,-10,-26,-15,  1,-21,-23,-13,-15, 22,-14, -3, -8,-16,  4,  8, -6,-10,-10,-27,-17,  0;
/M: SY='A'; M=  5,-18,-18,-20,-12, -8, -4,-14,-15,-11,-15,-11,-17,-20,-11, -6, -3,-10,-12,-21, -9,-12;
/M: SY='C'; M=  0,-30, 90,-40,-40,-20,-30,-30,-10,-30,-10,-20,-30,-30,-30,-40,-10,-10,-10,-20,-20,-40;
/M: SY='P'; M=-13,-12,-25, -9,-10,-15,-24,-15,-10,-15,-12,-13,-16,  3,-11,-17,-11, -7, -9,-27,-12,-11;
/M: SY='P'; M= -8, -7,-27, -8, -2,-29,-13,-11,-25,  0,-26,-21, -5, 14, -1, -6, -1, -3,-18,-32,-21, -2;
/M:         M= -9, -9,-23,-10,-10,-20, -9,-14,-14, -9,-15,-11, -7,-20, -5, -7, -4, -5,-11,-24,-18, -9;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 9 in 5 different sequences
Number of true positive hits 9 in 5 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 90.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Feature key [info] DOMAIN
Feature description [info] Pacifastin
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
5 sequences

CVP4_PIMHY  (Q8T0W2    ), LCM_LOCMI   (P80060    ), MSPI2_MELSA (B3A0N9    ), 
SGP1_SCHGR  (O46162    ), SGP3_SCHGR  (O46163    )
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

MSPI1_MELSA (B3A0N8    )

		
PDB
[Detailed view]
10 PDB

1GL0; 1GL1; 1KGM; 1KIO; 1KJ0; 1PMC; 2F91; 2XTT; 3TVJ; 4DJZ

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission