Entry: PS51643

Forthcoming changes to the profile format
General information about the entry

Entry name [info] HD_CAS3
Accession [info] PS51643
Entry type [info] MATRIX
Date [info] APR-2012 (CREATED); OCT-2013 (DATA UPDATE); SEP-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51643
Associated ProRule [info] PRU00974

Name and characterization of the entry

Description [info] HD Cas3-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=184;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=179;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5043204; R2=0.0072739; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-43606.148438; R2=64.009178; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=1443; N_SCORE=13.0; H_SCORE=48759; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=550; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-41; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='D'; M=   5, -10,  36,  25, -67,  16, -18, -52,  22, -24, -87,  11,   7, -28,   0,  12, -25, -53,  -5,  15;
/M: SY='S'; M=   3, -91,  30,  23, -42,  18, -21, -48,  21, -48,-113,   6,   1, -10, -12,  44,   2, -48, -26,-109;
/M: SY='H'; M= -28, -73,   8,   7, -30,  30,  56, -57,  20, -49, -32,  39,   7, -14, -16,   9,  -4, -74,  -7,  14;
/M: SY='P'; M= -12, -38,  26,   9, -97,  -3, -35, -47,  16, -90, -64,   7,  64,  19,  31, -14,  -5, -18,-225, -12;
/M: SY='W'; M= -20, -34,   5,  14,  -5,  11,  -3, -21,   7, -68, -36,  -8,  28, -26, -13, -32, -19, -57, 110,  37;
/M: SY='H'; M= -67,-225, -92,  52, -84,-117,  86, -32,  20, -22, -72, -62,-214,  79, -20, -98, -29,  -4,-223,  12;
/M: SY='T'; M= -91,-116, -58, -52, -24, -61, -45,-119, -69,  30,-107, -55,  67, -43,  -6,  31,  70,-119,-223,  -2;
/M: SY='L'; M= -50,-217,-231,-224, -12,-120,-216,   4,-224,  90, -41,-107, -98,-218,-222,-221,-209, -12,   9,  -1;
/I:         I=-7; MD=-18;
/M: SY='E'; M=   2, -36, -14,  29, -42, -91, -27,   5,  15,  -2, -57, -34,  10,  10,   5,  -3,  -7,   6,  14,  -1; D=-7;
/I:         I=-7; MD=-18;
/M: SY='E'; M=  -5,  22,  60,  64, -60, -51, -18,-104, -38, -74, -92, -24, -99,  25, -31, -40, -26, -61, -13,  19; D=-7;
/I:         I=-7; MD=-18;
/M: SY='H'; M=-221,-233,-205,-205,-219,-223, 155,-238,-210,-220,-205,-194,-221,-199,-204,-210,-219,-237,-255,-188; D=-7;
/I:         I=-7; MD=-18;
/M: SY='L'; M= -30,  38,-223,-138,-129, -86,-118,  -5,-219,  58,  21, -13,-226, -34,-222,  28,  36, -19,-230,-211; D=-7;
/I:         I=-7; MD=-18;
/M: SY='L'; M=  -8, -68,   5,  29, -25, -76, -17, -16,   5,  34, -15,  -5,-222,  20,   5, -15, -28, -50,  -8, -36; D=-7;
/I:         I=-7; MD=-18;
/M: SY='D'; M= -15,-125,  76,  21, -78,  15, -29, -79, -27, -24,-127,  42,-219, -20, -11, -21, -59,-122, -48,-219; D=-7;
/I:         I=-7; MD=-18;
/M: SY='V'; M= -10,  -7,-127,-223,-209,-227,-229, -48,-221, -17, -32,-127,-225,-223,-225, -19,  49,  86,-237,-215; D=-7;
/I:         I=-7; MD=-18;
/M: SY='A'; M=  68, -63,-220, -52, -75,  -1, -84, -18, -14,  13, -32, -68,-222, -47, -31, -12, -52, -20, -30, -10; D=-7;
/I:         I=-7; MD=-18;
/M: SY='A'; M=  43,  -7,   9,  43, -90, -63, -22, -41,  21, -96, -48,  20,-219,   4,  -1, -35, -38, -83, -48, -29; D=-7;
/I:         I=-7; MD=-18;
/M: SY='V'; M=  10,  29,-138, -12, -44, -93,-220,   1, -81,  13,   2,   0,-229, -25,   3, -69, -57,  43,  -3,  23; D=-7;
/I:         I=-7; MD=-18;
/M: SY='A'; M=  66,  22,-228,-223,  21,  -6,-224, -55,-141,  -6,  28,-122,-228,-221,-226, -39, -44, -12,  -5, -24; D=-7;
/I:         I=-7; MD=-18;
/M: SY='E'; M= -27, -57, -12,  49, -82, -14, -47,-142,   5, -33, -33, -13,-229, -37,  36, -53, -60,-126,  -9, -15; D=-7;
/I:         I=-7; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='R'; M= -11, -50, -70, -23, -45, -88, -31, -12, -19, -11, -47, -54, -76, -13,  16, -55, -49, -26, -44, -51; D=-7;
/I:         I=-7; DM=-18;
/M: SY='R'; M= -18, -45, -34, -62, -36, -59, -24, -30,  13, -17, -26, -20, -37,  -3,  18, -26, -41, -65, -88, -84; D=-7;
/I:         I=-7; DM=-18;
/M: SY='K'; M= -23, -67, -22, -19, -35, -85, -39,  -4,   9,  -3, -19, -13, -56, -21,   4, -30, -33, -44, -18, -16; D=-7;
/I:         I=-7; DM=-18;
/M: SY='L'; M= -22, -57, -49,  -6,  11, -65, -21,   1, -10,  13, -59, -32, -13, -10,  -7, -21, -50, -16,  -3, -44; D=-7;
/I:         I=-7; DM=-18;
/M: SY='L'; M=  17, -29, -21,  -8,   0, -72, -70, -14, -17,  18,-104, -43, -46, -14,  -8,  11, -50, -55,  -1, -21; D=-7;
/I:         I=-7; DM=-18;
/M: SY='A'; M=  17, -20,   0,   2, -25, -18, -25, -45,   3, -15, -82,  -3, -33, -28,  12,   4, -41, -24, -85, -26; D=-7;
/I:         I=-7; DM=-18;
/M: SY='R'; M=   6, -12, -16,   8,  -9, -21, -47, -17, -13,   4,  -4, -35, -35,   1,   9,  -5, -26, -28, -10,   8; D=-7;
/I:         I=-7; DM=-18;
/M: SY='L'; M=  -8, -54,   2,   1,   3,   4, -47,  -6,  -2,  15, -28,   4,  -5,  -2,  -3,   9,  -9, -55,   8, -43; D=-7;
/I:         I=-7; DM=-18;
/M: SY='F'; M= -17, -29,  -6,   6,  39,  19, -10,  -1, -26,  -3, -49,   8,  -6, -26, -11, -11, -47, -30, -17,  18; D=-7;
/I:         I=-7; DM=-18;
/M: SY='A'; M=  23,  17, -10,  10, -20,  11, -34,  14, -33,   8,   4, -25,  -7, -14, -43, -14, -14, -30,  12, -24; D=-7;
/I:         I=-7; DM=-18;
/M: SY='D'; M= -20, -60,  33,  25, -15,   1, -33, -27, -15,   4, -45,  19,   5, -21, -13,   6,   1, -30, -73, -20; D=-7;
/I:         I=-7; DM=-18;
/M: SY='P'; M= -10, -65,  23,  27, -35,  -8, -81, -15,  21, -29, -53,   2,  29,  -9,   4,   3, -14, -21,   6, -29; D=-7;
/I:         I=-7; DM=-18;
/M: SY='E'; M= -27, -64,  32,  62,  21,  -7, -15, -17,   5, -57, -83,  -8,  26,   0, -32,   0, -42, -59, -22, -57; D=-7;
/I:         I=-7; DM=-18;
/M: SY='E'; M= -25,-107,  35,  37, -21,  21,  -6, -16,   7, -11, -47,  -1, -22,  15,  -3,  -9, -14, -10, -22, -66; D=-7;
/I:         I=-7; DM=-18;
/M: SY='L'; M=  20, -38,  -5, -34,  41, -49, -66,  27, -55,  46,  10, -71,-136, -38, -93, -43, -43,  13,  11, -12;
/M: SY='W'; M=  -2, -32, -20,  24, -55,  -5, -49,  -3,  32, -20, -63, -67, -14,  16,  42,  -1, -40, -21,  70, -19;
/M: SY='E'; M=  12, -60,  37,  49, -52, -55,   3, -59,  17, -19,-110,  18, -25,  23,  26,   7, -24, -81,-226, -59;
/M: SY='W'; M=   9, -23, -24, -76,  -9, -75, -30,  25, -78,  53,  23, -56, -60, -28, -14, -35,  -5, -13,  80, -32;
/M: SY='L'; M=  38, -23,-132, -78,  12,   6, -88,  27,-217,  43,   0, -75,-222,-215, -94, -29, -21,  33, -77, -28;
/M: SY='Y'; M=  16,   8, -49,  28,  22, -20, -37, -22,  20, -17, -15, -99, -59, -18,  35, -32, -21,  -1,  10,  37;
/M: SY='W'; M=  -7, -28, -70, -38,  53,-144, -51,  26, -27,  46, -12, -24,-124, -45, -42, -64, -14,  -2,  58,  17;
/M: SY='A'; M=  69,  15,-220,-215,  -2, -45,-104,  22,-215,  29,   8, -91,-126,-136,-218,  -3,  -8,  -5,   0, -70;
/M: SY='G'; M=  58,  54,-218,-218, -93,  59,-220,  19,-107,  -9, -75,-209,-117,-214,-221, -55, -39,   9,-224, -83;
/M: SY='L'; M=  31, -26, -75, -29,  22,  -2, -81,  -3, -35,  52,  -8,-118,-223, -51, -12, -60, -86, -12,  23,  31;
/M: SY='W'; M= -30,  27,-227,-222,  47, -66, -16, -17,-220,  62,  23,-103,-227,-111,-219, -37, -14, -24,  70,  41;
/M: SY='H'; M=-217,-228,-200,-131,-215,-218, 159,-233,-205,-216,-201,-190,-217, -78,-199,-206,-215,-233,-250,-184;
/M: SY='D'; M=-215,-228, 130,-178,-235,-212,-200,-233,-202,-232,-231,-182,-214,-201,-211,-203,-204,-230,-251,-218;
/M: SY='I'; M= -29,-104, -53, -98,  45,-148, -96,  65,-149,  52, -27,-223,-132,-219,-140, -52, -60,  15,  39,  -8;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='G'; M= -51,-223,-212,-223,-138, 111,-218,-237,-217,-233,-222,-198,-215,-214,-224,-132,-215,-230,-221,-225;
/M: SY='K'; M=-210,-224,-202,-188,-226,-217,-205,-226, 121,-225,-213,-195,-210,-187,-171,-204,-126,-222,-219,-213;
/M: SY='A'; M=  66,  20,-106,-114,  27, -40,-108,  19,-119,   7, -24, -92,-221, -65, -68, -17, -50,  -4,-211,  49;
/M: SY='T'; M=   8, -37,  24, -85,-131, -56,  41, -79, -71, -72,-120,  60,-213, -50, -31,  57,  63, -95,-233, -71;
/M: SY='P'; M= -11, -16,  16,  24, -51, -66, -19, -31,  -4, -32,-101, -58,  73,   0,  16,  22,   6, -21, -73, -53;
/M: SY='Y'; M=  30, -49,  -1,  17,   8,  18,   1, -36,  -4, -30,-207,  11, -28,  -3,  24, -11, -47, -47, -57,  40;
/M: SY='F'; M=-222,-221,-234,-229, 125,-229,-108,-198,-224,-190, -59, -79,-232,-112,-222,-221,-143,-138,  78,  25;
/M: SY='Q'; M= -78, -71, -59,-107,-122,-215,-196, -85, -89, -81,-204, -98,-214, 140, -92,-196,-100,-104,-220,-124;
/M: SY='R'; M=  17, -13,  23,  35, -51, -31, -24, -32,  25, -49, -34,  31,-215,  35,  40, -14, -18, -83, -49, -36;
/M: SY='Y'; M= -29,-107, -63, -60, -73, -58, -19, -84,  57, -17,  43, -21, -90,  31,  33, -32, -56, -71,  17,  83;
/M: SY='L'; M= -34, -56, -58, -96, -24,-120, -96,  54, -13,  63, -12, -57, -58, -60, -10, -68,-207,  14,   1, -14;
/M: SY='R'; M= -28, -38, -14,  13, -38,  -9,  -8, -75,  24,   1,  16,  -3,   8,  23,  55, -14,  -5, -46,   2, -30;
/M: SY='G'; M=  -1, -67,  13,  12, -53,  40,   3, -50,  28, -47,-115,  29,   0,   0,   2,  11, -10, -71, -17, -16;
/I:         I=-5; MD=-12;
/M: SY='N'; M=   2, -23,   3,  10,-101,  23,-122, -33,   7, -20, -36,  44,  -2,   8,  -3, -12, -43, -54,   7, -34; D=-5;
/I:         I=-5; MD=-12;
/M: SY='K'; M=  -9,   3,   6,   9, -92, -14, -48, -33,  29, -42,  -7,  17, -48,   7,  -6, -11,  -6, -44,   3, -36; D=-5;
/I:         I=-5; MD=-12;
/M: SY='E'; M= -28, -81,   1,  15, -76,  -2, -43, -66,   3, -56,-112,  13, -13,   5, -23, -20, -15, -82, -47, -49; D=-5;
/I:         I=-5; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='D'; M= -24, -84,  -5,  -7, -36, -30, -45, -56, -16, -44, -78, -27, -11, -11, -27, -30, -48, -69, -60,  -9; D=-5;
/I:         I=-5; DM=-12;
/M: SY='P'; M= -22,-110, -15, -18, -70, -38, -36, -41,  19, -58, -53, -11,  24, -69,   3, -28, -27, -32, -88, -51; D=-5;
/I:         I=-5; DM=-12;
/M: SY='P'; M= -29, -49,  -4,  12, -28, -28, -64, -48,  -4, -25, -81, -54,  28, -11,  -7,  12, -30, -47, -83,-120; D=-5;
/I:         I=-5; DM=-12;
/M: SY='K'; M= -40,-233, -12,  -3, -48,  16, -20, -38,  19, -19, -80, -16,   6, -12,   8,   9, -29, -32, -27, -30; D=-5;
/I:         I=-5; DM=-12;
/M: SY='K'; M= -35, -42,   9,  -5, -29,  -9, -23, -25,  31, -20, -15,   9,  13, -13,  23,   5, -20, -29, -35, -10; D=-5;
/I:         I=-5; DM=-12;
/M: SY='R'; M= -14, -41, -19, -24, -55,  14, -17, -15,  20, -42, -63,  -3,  37, -30,  38,  20, -25, -29, -11, -13; D=-5;
/I:         I=-5; DM=-12;
/M: SY='W'; M= -57, -56,  29,  -1, -67,  14, -18, -33,  32, -31, -33, -10,  28,  16,  15,  17, -27, -36,  45, -12; D=-5;
/I:         I=-5; DM=-12;
/M: SY='H'; M= -33, -60,  -4,  26,   5,  27,  29, -84,  26, -12, -75,  -5,  27, -26,  26,   0, -36, -55, -33,  -3;
/M: SY='Y'; M= -15, -45,-107, -33,  25, -53,  -5,  30,  -6, -21, -31,-132,  24, -53, -26,   6,   3,  38,  39,  42;
/M: SY='R'; M= -65, -55,  40, -48, -50, -25,  29, -97, -36, -87,-213,  19,  54, -29,  80,  -9, -32,-105, -96,  -2;
/M: SY='H'; M=-216,-228,-200,-201,-215,-218, 159,-233,-205,-216,-201,-190,-217,-194,-199, -80,-215,-233,-250,-184;
/M: SY='E'; M=  41,-218,  -7,  72,-138,   7, -75, -94, -84,-133, -71,   9, -36,-195,-125,  56, -40,-110, -32,-125;
/M: SY='W'; M=  -5, -35, -45, -29,  24, -67,  -5,  21, -71,  25, -39,-105, -25, -46, -16,  -2,  42,  10,  73,  -2;
/M: SY='L'; M=  47, -73,-137, -18, -16, -50, -62,  33, -72,  50, -57,-125, -34, -59, -95, -35, -89,  14,  15,  -7;
/M: SY='S'; M= -49,-215,-206,-128,-224,  69,-106, -81,-209,-163,-218,-194,-131,-203,-214,  95, -14,-130,-226,-217;
/M: SY='A'; M=  73, -10,-216, -47, -28,   1, -51, -44,-139,  19, -37,-210, -46,  -3,-105,  -1, -27,  -3, -52,   4;
/M: SY='W'; M=  29, -13, -88, -36,  29, -60, -59,   6,   0,  28, -47, -91, -11,   0,  22, -51,-135,  -2,  51,  32;
/M: SY='F'; M=   0, -35, -78, -44,  62,-126, -28,  24,-134,  51,  -3,-221,-132,-137,-106, -68, -33,  -3,  52,  36;
/M: SY='W'; M=  28, -18,-136,-109,  42, -58,-218,  20,-219,  48, -28,-220,-224,-217,-220, -30, -15,  26,  52,  11;
/I:         I=-4; MD=-11;
/M: SY='Y'; M=  -2, -42,  -6,  -6,   4, -66, -24, -48, -30,  -5,  -3,   2,   1,  26,  -9, -22, -41, -46,  46,  46; D=-4;
/I:         I=-4; MD=-11;
/M: SY='Y'; M=  22, -79,  11,  10, -32, -84,   8,-111, -27, -61,-225, -33, -81,  13,  10, -23, -60, -63, -52,  27; D=-4;
/I:         I=-4; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='W'; M= -55, -47, -16, -13,  -8, -48, -32, -29, -10,  -5, -71, -48, -12, -37, -51, -18, -72, -57,  11,  -6; D=-4;
/I:         I=-4; DM=-11;
/M: SY='W'; M= -42, -44,  -5,  -4,  -4, -43, -13, -11, -20,   1, -63, -13, -13, -30, -35,  -4, -35, -43,  12,  -9; D=-4;
/I:         I=-4; DM=-11;
/M: SY='L'; M= -25, -16, -49,   2, -38, -39,  -5, -21,   2,  15, -78,   4,   2, -14, -11, -15, -24, -58,  -3, -29; D=-4;
/I:         I=-4; DM=-11;
/M: SY='E'; M= -29, -56,  18,  18, -58, -49, -29, -40,   8,  -9, -52,   9,  -6, -10,  -7,  15, -10, -44,  -2, -27; D=-4;
/I:         I=-4; DM=-11;
/M: SY='E'; M= -19, -22,  14,  26,  -9, -23, -22, -31,   3, -17,-109,  13,  19,  17,  -2,   1, -40, -44, -11, -52; D=-4;
/I:         I=-4; DM=-11;
/M: SY='W'; M= -22, -29,  -2,  14,   0, -14, -11, -31,  22,  13, -46,  15, -26,   0,  -2,  -6,  -8, -49,  23, -36; D=-4;
/I:         I=-4; DM=-11;
/M: SY='G'; M= -21, -13,  20,   9,  -3,  27, -22, -33,  15, -19, -96,   1,   9, -28,   5,   1, -21, -43,  11, -58; D=-4;
/I:         I=-4; DM=-11;
/M: SY='W'; M= -15,  -6,   6,   8,  17, -16,   4, -13,  14,  15, -43,  -7, -30,   1, -29,   2, -28, -46,  51,  16; D=-4;
/I:         I=-4; DM=-11;
/M: SY='D'; M= -26, -39,  47,  14, -24, -15, -31, -50,  -4,  10, -36,  15,  24,   4, -21,  17, -37, -41,  16,  -2; D=-4;
/I:         I=-4; DM=-11;
/M: SY='P'; M=   0, -85,   4,  38, -14,  -1,  -9, -53,  27, -29, -69,  20,  42,  -8,  17,  -4, -19, -70, -19, -37;
/M: SY='E'; M= -25, -60,  16,  38,  -5,   2,   8, -12,  -1, -12, -40,  -5,  37,   2,   7,  -8, -15, -19, -26, -13;
/M: SY='L'; M=  -2, -18,  21,   8,  16, -40,  -4,  -4, -50,  38,  -4, -18, -39, -31, -47, -33,   2,  15,   9,   2;
/M: SY='A'; M=  46, -18, -13, -74,  -3,  -4, -36,  -2,  -2,   6,  -6, -15,  12, -16,  18, -12, -27, -48,  21,   1;
/M: SY='R'; M= -25, -54,  25,  26,   3, -57,   7, -21,  11,  13,  -2,   1,   3,  23,  29, -25, -33, -37, -20,   6;
/M: SY='W'; M=  20, -57, -51, -58,  -4, -38, -39,  32, -77,  46,  -3, -39,   7, -35, -30, -24, -29,   6,  54, -20;
/M: SY='W'; M=  13, -48,-225, -78,  -1, -34, -70,  44,-219,  42,  -9, -43,-147, -64,-221, -16, -45,  48,  57, -87;
/M: SY='A'; M=  54, -24, -81, -55,  26,  -7,-104,  -4, -62,  16,  16,-126, -73, -35, -37,  13,  -6, -15,   1,  23;
/M: SY='W'; M=   9, -41, -47, -18,  13, -81,  26, -31, -56,  22, -11, -10, -54,   5,  -1, -22, -11, -23,  74,  69;
/M: SY='A'; M=  64,  47, -59,-119, -56, -40,-218,  17,-215,  29, -18, -79, -22,-129,-219,  -3, -23,  20,-225,-211;
/M: SY='I'; M= -17, -57,-229,-122,-129,-152,-229,  87,-222, -19, -50,-222, -66,-221,-225, -53, -34,  70,-226,-207;
/M: SY='A'; M=  52, -22,-109,-106, -21,  21, -65,  -3, -26,  31,  27, -67,-219, -59, -21, -10, -18,  -2, -39, -13;
/M: SY='G'; M=  17,  -3, -71,-119, -23,  53,   7,-111,  -1, -23, -55, -11,-216, -43,  23,  42,  15,-152,  -7, -10;
/M: SY='H'; M=-216,-228,-200,-201,-215,-218, 159,-233,-205,-216,-201,-190,-217,-194,-199, -58,-214,-232,-250,-184;
/M: SY='H'; M=-149,-228,-201,-201,-214,-139, 159,-232,-206, -80,-200,-190,-217,-195,-200,-206,-215,-232,-250,-184;
/M: SY='G'; M= -13,-221, -54, -31,-222,  78, -26,-158,   1, -88,-216, -10,-215, -34,  25,  28,   7,-221,  -8, -23;
/M: SY='R'; M= -13,-222,  16, -74, -34,  29,  17, -37,  22,  -5, -25,  18,   9, -28,  46,  -8, -37, -41, -25,   7;
/M: SY='P'; M= -37, -32, -46, -43,  33, -22, -29,   7, -65,  55,   1, -63,  62, -72, -41, -51, -61, -26,   1, -30;
/M: SY='P'; M= -30, -46,  14,  -7, -28, -22, -15,  -1,   6, -15, -11, -21,  62, -15,  31,  -8,  -5,  -6, -46,  -1;
/M: SY='D'; M= -43, -19,  63,   2, -24, -25, -48, -41,  -8, -19, -18,  48,  27, -21, -15,  17,  -9, -36, -46, -22;
/M: SY='P'; M= -15,  18,  17,  -2,  25,  -8,  -6,  -3, -24,  14, -21,  -9,  27, -30, -11,  -5, -33,  -2,  26,  -2;
/M: SY='D'; M= -15, -69,  37,  17, -19,   9, -12,  -7, -19,   8,   2,  16, -22,   7, -15,  13, -11, -18, -39, -10;
/M: SY='D'; M= -27,-109,  49,  29, -31,  -1, -12, -50,   8, -23, -26,  27,  13,   2,   2,   2,   0, -47,-223,  13;
/M: SY='E'; M= -12, -29,  25,  26,  -2, -30,   5,   3,  -1,   4, -22,  10,  18,   8,  -7,  -1, -35, -25, -43,  17;
/M: SY='D'; M= -24,  -3,  30,  10,   5,  -3, -18,  -7,   5,   2, -36,  10, -25, -25,  18,  14, -14, -12, -23,   4;
/M: SY='D'; M= -19, -82,  29,  22,  -7,   1,  -1,  -3, -13, -12, -57,  13,  21, -14,   5,  14,  -5, -20, -11,   5;
/I:         I=-6; MD=-15;
/M: SY='D'; M=  -1, -59,  24,   9, -25, -12, -25,  -7,   7,   7, -41,  12,  22,   2,   7,   5, -29, -29, -24, -28; D=-6;
/I:         I=-6; MD=-15;
/M: SY='W'; M= -10, -37,  24,  24, -11, -16, -13, -26,  -1,  -8, -37,   6,   8, -11,  11,  -1, -10, -38,  25, -28; D=-6;
/I:         I=-6; MD=-15;
/M: SY='D'; M=   7, -48,  15,  14,   4, -21, -29, -29,   6, -18,   5, -13,   8, -28,  -4,   0, -44, -31, -56,   6; D=-6;
/I:         I=-6; MD=-15;
/M: SY='P'; M= -12,  -9,  14,   1,  -9, -28, -19, -48, -11, -25, -40,  -6,  21, -14, -15,   5, -40, -28, -54,  21; D=-6;
/I:         I=-6; MD=-15;
/M: SY='D'; M= -28,-101,  20,   5, -10, -27, -52, -36, -37,  -5, -62, -15,  16, -33,  -6, -17,  -6, -68,   1, -11; D=-6;
/I:         I=-6; MD=-15;
/M: SY='D'; M= -36, -58,   1,  -1, -44, -19, -60, -15, -19, -17, -76, -17,  -5, -49, -16,  -9, -20, -31,   1,  -2; D=-6;
/I:         I=-6; MD=-15;
/M: SY='D'; M= -45, -73,   9,  -5, -53, -15, -87, -45, -20, -32, -72,  -7,   2,-118,  -1, -29, -38,-100,   3, -28; D=-6;
/I:         I=-6; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='W'; M=-162, -18,  34, -73,  -5, -91, -48, -89,-102, -14, -96, -25, -72, -36, -68,-100, -86,-243, 112, -51; D=-6;
/I:         I=-6; DM=-15;
/M: SY='K'; M= -27, -13, -25,  10, -43,-108, -55, -10,  15, -87, -79, -44, -17,  14,  10, -26, -58, -39,-245, -47; D=-6;
/I:         I=-6; DM=-15;
/M: SY='E'; M=   4,-240, -11,  29,-244, -33, -66, -99,  15,-110, -56, -14, -28,  24, -29, -12,   1, -80,-246,-235; D=-6;
/I:         I=-6; DM=-15;
/M: SY='A'; M=  30, -43, -27,  -7, -26, -57,-228,  16, -27, -33, -23, -36,-138,   6, -61, -36, -28,   1, -33, -26; D=-6;
/I:         I=-6; DM=-15;
/M: SY='R'; M=  17, -41, -16, -59, -44,-130,   2,   6, -18,   0,-106, -67, -27,  10,  37, -47,-112, -67,  28,   7; D=-6;
/I:         I=-6; DM=-15;
/M: SY='E'; M=  -5,-114,  27,  37,-106, -81, -59, -59,  32, -87, -65,  17,-222,  32,  31, -29, -39, -46, -39, -90; D=-6;
/I:         I=-6; DM=-15;
/M: SY='E'; M=   1, -43,  39,  53, -91, -69,   5, -66,  10, -78,-103,  14, -70,  10,   4, -30,   6, -39, -88, -94; D=-6;
/I:         I=-6; DM=-15;
/M: SY='F'; M= -59, -27, -76, -35,  58,-105,  31,  10, -50,  39,   7,-127,-105,   6, -94, -67, -28, -13,  39,  28; D=-6;
/I:         I=-6; DM=-15;
/M: SY='L'; M=  24, -38, -36, -31,  17, -84, -15,  35, -14,  45, -10,-125,-223, -57, -53, -35, -31,  19, -41, -43; D=-6;
/I:         I=-6; DM=-15;
/M: SY='E'; M= -23, -22,  36,  52,-224, -12, -15,-115,  30, -31, -65,  21, -11,  41,  37, -33, -39, -76,-227,-110;
/M: SY='R'; M=   2,-223,  35,  44, -19, -21,  -1, -67, -10, -25, -61,   0, -71, -21,  53, -25, -14, -38,  46,   1;
/M: SY='I'; M=  17,   0,-131,-221, -13, -41,-123,  48, -68,  45,  42,-220,-223,-217,-151, -63, -32,  40,  35, -35;
/M: SY='K'; M=  10, -60,  -4,  26,  -7, -82,  -9, -34,  38,  18, -36,   0,  -9,  -3,  17,   1, -28, -29,  24, -56;
/M: SY='E'; M=   8, -56,  44,  53,-225, -34,  -8,-116,  38, -93,-214,  10, -58,  25,   9,  13, -11, -41,-228, -73;
/M: SY='L'; M=  -6,   1,  -4,  21,   1, -39,  26,  17, -22,  30, -26, -11, -53,   9, -14, -57,  -9,  -5,  29,   7;
/I:         I=-8; MD=-20;
/M: SY='W'; M=  -2,   5, -17, -36,  42, -39,-214,   9, -30,  37, -99,  -8, -46,-213, -34,  -9,   0, -15,  60,  19; D=-8;
/I:         I=-8; MD=-20;
/M: SY='P'; M= -59,-125,  27,  19, -47,  34, -32, -38,   9, -18, -83,  28,  38,  32, -69, -10, -31, -79, -33, -44; D=-8;
/I:         I=-8; MD=-20;
/M: SY='E'; M=   1, -57,  19,  20,  13, -63, -12,   1,  -4, -19,-209,   1,  -1,   4,-111,   9, -10, -12, -21,  15; D=-8;
/I:         I=-8; MD=-20;
/M: SY='W'; M= -32,-125,  19,  -7,  -6, -32, -41,  -3, -26,   7, -14,   1,  14, -13, -61,  -5,   1, -40,  50,  15; D=-8;
/I:         I=-8; MD=-20;
/M: SY='D'; M= -15, -51,  13,   2, -13,   2, -25,  -2, -30,   7, -49, -16,   5,-108,  -9, -14, -36, -60,  -6,  -8; D=-8;
/I:         I=-8; MD=-20;
/M: SY='Y'; M= -16, -59, -14, -14, -60, -14, -72, -11, -14,  -8, -84,  -8,   0, -26, -13, -22, -18, -33, -12,  20; D=-8;
/I:         I=-8; MD=-20;
/M: SY='E'; M= -63, -29, -13,  21, -64, -42, -41, -45,   3,  -8,-100, -69, -32, -14, -27, -20, -56, -27, -11,   6; D=-8;
/I:         I=-8; MD=-20;
/M: SY='W'; M= -30, -63, -13, -26, -54, -38, -32,   3, -14, -30, -25, -46, -24, -22, -22, -43, -27, -43,  10, -15; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='W'; M= -90,-235,  -3,  40, -21, -71,   1, -52, -41, -32, -96,  21, -38,  -5, -49,  16, -43,  -6,  51,   9; D=-8;
/I:         I=-8; DM=-20;
/M: SY='W'; M= -41,-228,-226, -19,   9,-230,-121,  21, -44,  46, -10, -92,  43, -15,  12,-122,-214, -10,  69, -27; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P'; M=   1, -39,  20,  50, -61, -43,  19, -84,  10, -45, -48,   3,  56,  20,  25,  -5, -46, -78,-226, -62;
/M: SY='E'; M= -23,-225,  43,  57,-228,  15, -13,-228,  25,-225,-217,  13,  20,   3,  36,   6, -47,-223,-228,-217;
/M: SY='I'; M= -61,-219,-131,-222,  32,-124, -60,  57, -76,  54, -29, -62, -45, -79, -52, -75, -25,  25,-212,  34;
/M: SY='P'; M= -34,   6,  27,  -6, -21,  -6,-210,   4,   7, -12,  -1,   7,  55, -25, -12,  13,  17, -39,  -7, -93;
/M: SY='L'; M= -13, -43,  -2,  12,  11, -34, -25,  17, -30,  30, -30, -22,  15, -10,  18,  18,  -3, -55, -22, -31;
/M: SY='P'; M=  -1, -80,  35,  32, -91, -37, -20, -25,  29, -26, -60,   1,  47,  15,   2,  14, -13, -62,-226, -57;
/M: SY='D'; M= -14, -72,  44,  38,-110,  -6,-206,  -6,   1,  -8,-208,  -3,   3,  22,   0,  20, -30, -38,  15,  -4;
/M: SY='E'; M=   3,-222,  24,  27,  10, -22, -21, -12,   8,   8, -22,  -2,  23, -17,   4,   8, -17, -92,   3,  -7;
/I:         I=-7; MD=-19;
/M: SY='W'; M=-217,-231, -41,  25,   7, -70, -74, -68,  33,   8, -94,   0,  10,   5, -76,   7,   0, -18,  37, -73; D=-7;
/I:         I=-7; MD=-19;
/M: SY='W'; M= -68,-241,  -8,  26,-152, -65,-101, -16,  17, -33, -55,   7, -19,  15, -39,   7,-100, -45,  47, -88; D=-7;
/I:         I=-7; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='W'; M= -41,-124,  -6,  -9, -30, -80, -88, -58,  -3, -24,-106,  -6, -10, -19, -14, -48, -40, -45,  -2, -40; D=-7;
/I:         I=-7; DM=-19;
/M: SY='R'; M= -22, -10,   8, -23, -53, -20, -65,-241, -29, -53, -55,   6,  -3, -33,  10,  -4, -53, -60, -59, -50; D=-7;
/I:         I=-7; DM=-19;
/M: SY='F'; M= -52,-106, -14,  11,  38,-114, -29,  -4, -37, -33, -29, -19, -54, -40,  -5, -49, -39, -36,  -5, -27; D=-7;
/I:         I=-7; DM=-19;
/M: SY='Y'; M= -15,-126,  -3,   7, -49, -78, -22, -73,  -4, -25, -25, -42, -67,   7,   6,   9, -71, -55,-233,  36; D=-7;
/I:         I=-7; DM=-19;
/M: SY='L'; M= -36, -61,   6, -56,  21,  -2,   2, -24, -42,  24, -12, -35, -49, -49, -13, -61, -46, -71,   7,   7; D=-7;
/I:         I=-7; DM=-19;
/M: SY='Y'; M= -23,-234, -50, -44,  18,  -6, -26, -99,  -8, -54, -47,  -9,  22, -21,  14,   3, -51, -82,  50,  57; D=-7;
/I:         I=-7; DM=-19;
/M: SY='W'; M= -13, -18, -45, -45,  50, -51, -86,  -3, -23,  18,  14, -52,  15,  -6,  -3, -41, -24, -23,  53, -17; D=-7;
/I:         I=-7; DM=-19;
/M: SY='F'; M=   9,   5, -35, -30,  43, -18, -39, -18, -14,  37, -28, -22, -85,  -9, -10, -66, -44, -26,  25,  27; D=-7;
/I:         I=-7; DM=-19;
/M: SY='Y'; M=  13,  -1,-217, -58,  12, -25, -20,   8, -97,  26,  -7, -41, -78,   7, -51,   9,  25,  12,   0,  51;
/M: SY='W'; M=  11,-222, -58, -77, -40,-116,  24,  13,   2,   4,   1,  -6, -33,   0,  59, -10, -39,  15,  66, -83;
/M: SY='M'; M= -22, -63, -99, -66,  43,-103,  12,   3, -35,  45,  72,-138, -58, -25, -25, -53, -62, -28,  27,  53;
/M: SY='L'; M= -60, -27,-126, -99,  12,-154, -48,  25,-110,  76,  13, -63, -57,-125,-112, -33, -68,  16,  -3, -22;
/M: SY='F'; M=  28, -46,-211,  13,  59,-119, -54,-206,  25, -12, -62, -31,-218, -40,  -1,   5,  12, -33, -12,  54;
/M: SY='S'; M=  19,-217,-208,-211,-142,  74, -53,-225, -89,-100,-116,-197, -87,-204,  -1,  76, -36,-135,-225,-218;
/M: SY='C'; M=  10,  70,-226,-102,  12,-126,-218,  25,-218,  62,   1, -81, -53,-216, -23, -29, -42,  -1, -39, -93;
/M: SY='L'; M= -53,  -2,-143,-106, -72, -96,-218, -16,-222,  84, -40,-224,-135,-114,-221, -52, -10,  34,-222,-203;
/M: SY='I'; M= -73, -52,-103,-133,-204,-124,  12,  58, -31,   2,  36,   6,-220, -31,  28,  -5,  19,  47,-227,-115;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='D'; M=  16,-100,  66, -71, -27,-110, -74, -22, -30,  38,  27, -27,-219, -54,   6, -20, -12,   8, -40, -57;
/M: SY='A'; M=  90,  67,-215,-210,-129, -33,-216, -34,-211, -52,-108, -61,-216,-208,-216,  32, -61, -90,-225, -85;
/M: SY='D'; M=-215,-228, 129,-131,-235,-119,-200,-233,-113,-232,-230, -90,-127,-201,-210,-120,-204,-230,-249,-110;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='W'; M= -97,-230,-217,-209,  23,-114,  87, -80,  26,-109, -45, -60,-222, -20,  40, -48,-215, -50, 130,  50;
/M: SY='L'; M=  13, -77,-105, -27,   0,-117,-213,  43, -70,  48,   8, -64,-221, -85, -22,  18,  18, -36,-216,  23;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_10 which contains 546'790 sequence entries.


Total number of hits 12 in 12 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] HD Cas3-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
12 sequences

CAS3_ECOLI  (P38036), CAS3_METJA  (Q57821), CAS3_METTH  (O27158), 
CAS3_MYXXD  (Q1CW46), CAS3_PECAS  (Q6D0W9), CAS3_PSEAB  (Q02ML8), 
CAS3_STRTR  (F2XG53), CAS3_THET8  (Q53VY2), CS3HD_METJA (Q57829), 
CS3HD_PYRFU (Q8U336), CS3HD_SULSO (Q97WW0), CS3HD_THETK (G4RJZ4)
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PDB
[Detailed view]
3 PDB

3S4L; 3SK9; 3SKD

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission