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Imidazoleglycerol-phosphate dehydratase (EC 220.127.116.11) is the enzyme that
catalyzes the seventh step in the biosynthesis of histidine in bacteria, fungi
and plants. In most organisms it is a monofunctional protein of about 22 to
29 Kd. In some bacteria such as Escherichia coli it is the C-terminal domain
of a bifunctional protein that include a histidinol-phosphatase domain .
We developed two signature patterns that each include two consecutive
April 2006 / Pattern revised.
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