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annotation rule: PRU00295

General rule information [?]

Accession PRU00295
Dates 12-DEC-2003 (Created)
16-DEC-2016 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS50189; NTR
Name NTR domain
Function The NTR domain is implicated in inhibition of zinc metalloproteinases of the metzincin family.

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS50189
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       NTR #        
DISULFID     1     76           disulf   C-x*-C   1
case <FTGroup:1>
DISULFID     5     78           disulf   C-x*-C  
DISULFID     5     107           disulf   C-x*-C  
end case

DISULFID     19     134           disulf   C-x*-C   1

Additional information [?]

Size range 110-200 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example P97299 (SFRP2_MOUSE)
Scope Eukaryota


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]