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annotation rule: PRU00352

General rule information [?]

Accession PRU00352
Dates 17-AUG-2004 (Created)
16-DEC-2016 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS51004; SEMA
Name Sema domain
Function The 500 amino acid Sema domain is a receptor recognition and binding module.

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS51004
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Sema #        
DISULFID     74     85           disulf   C-x*-C   1
DISULFID     103     112           disulf   C-x*-C   1
DISULFID     234     344           disulf   C-x*-C   1
DISULFID     258     304           disulf   C-x*-C   1

Additional information [?]

Size range 400-520 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example Q9H2E6 (SEM6A_HUMAN)
Scope Eukaryota; Metazoa


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]