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annotation rule: PRU01066

General rule information [?]

Accession PRU01066
Dates 24-SEP-2014 (Created)
19-DEC-2016 (Last updated, Version 4)
Data class Domain
Name Biotinyl/lipoyl domain
Function Biotin and lipoic acid moieties are the covalently bound cofactors of several multicomponent enzyme complexes that catalyze key metabolic reactions. They are attached to a lysine residue, via an amide bond, by specific biotinyl and lipoyl protein ligases.

Propagated annotation [?]

Comments [?]

case <Feature:PS50968:41-42=M-K> or <Feature:PS50968:42-43=K-M>
Cofactor biotin
Note: Biotin.
else case <Feature:PS50968:42=K>
Cofactor (R)-lipoate
Note: Binds 1 lipoyl cofactor covalently.
end case

Keywords [?]

case <Feature:PS50968:41-42=M-K> or <Feature:PS50968:42-43=K-M>
else case <Feature:PS50968:42=K>
end case

Features [?]

case <Feature:PS50968:41-42=M-K> or <Feature:PS50968:42-43=K-M>
From: PS50968
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Biotinyl-binding #        
MOD_RES     42     42       N6-biotinyllysine     K  
DOMAIN     from     to       Lipoyl-binding #        
MOD_RES     42     42       N6-lipoyllysine     K  
end case

Additional information [?]

Size range 57-96 amino acids
Related rules None
Repeats 1-3
Topology Undefined
Examples P0A6T9 (GCSH_ECOLI); P0ABD8 (BCCP_ECOLI): [Recover all]
Scope Bacteria
Comments None


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UniProtKB rule member sequences [?]