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ProRule PRU10115


General rule information [?]

Accession PRU10115
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS01062; HMG_COA_LYASE
Name Hydroxymethylglutaryl-coenzyme A lyase active site
Function Undefined
Scope(s) Eukaryota
Bacteria
Example(s) P35914 (HMGCL_HUMAN);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name AltName: Full=Hydroxymethylglutaryl-CoA lyase;
                 EC=4.1.3.4;

Comments [?]

CATALYTIC ACTIVITY Reaction=(3S)-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA; Xref=Rhea:RHEA:24404, ChEBI:CHEBI:13705, ChEBI:CHEBI:43074, ChEBI:CHEBI:57288; EC=4.1.3.4;

Features [?]

From: PS01062
Key From To Description Tag Condition FTGroup
ACT_SITE 8 8

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]