A family of eukaryotic and prokaryotic proteins that seem to be mainly
involved in the intake of small peptides with the concomitant uptake of a
proton has been recently characterized [1,2]. Proteins that belong to this
family are:
Lactococcus proton-dependent di- and tri-peptide transporter dtpT.
Caenorhabditis elegans hypothetical protein C06G8.2.
Caenorhabditis elegans hypothetical protein F56F4.5.
Caenorhabditis elegans hypothetical protein K04E7.2.
Escherichia coli hypothetical protein ybgH.
Escherichia coli hypothetical protein ydgR.
Escherichia coli hypothetical protein yhiP.
Escherichia coli hypothetical protein yjdL.
Bacillus subtilis hypothetical protein yclF.
These integral membrane proteins are predicted to comprise twelve
transmembrane regions. As signature patterns, we selected two of the best
conserved regions. The first is a region that includes the end of the second
transmembrane region, a cytoplasmic loop as well as the third transmembrane
region. The second pattern corresponds to the core of the fifth transmembrane
region.
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