PROSITE documentation PDOC00944
Hypothetical cof family signatures


The following uncharacterized proteins have been shown [1] to share regions of similarities:

  • Escherichia coli protein cof.
  • Escherichia coli hypothetical protein ybhA.
  • Escherichia coli hypothetical protein yidA.
  • Escherichia coli hypothetical protein yigL and HI0597, the corresponding Haemophilus influenzae protein.
  • Bacillus subtilis hypothetical protein ycsE.
  • Bacillus subtilis hypothetical protein yxeH.
  • Haemophilus influenzae HI0003.
  • Mycoplasma genitalium hypothetical protein MG125.
  • Mycoplasma genitalium hypothetical protein MG263.
  • Mycoplasma genitalium hypothetical protein MG265.
  • Mycoplasma pneumoniae hypothetical protein A05_orf290.
  • Partial hypothetical proteins from Bacillus stearothermophilus and Mycoplasma capricolum.

There are hydrophilic proteins of about 250 to 280 amino acid residues. We have developed two signature patterns for these proteins.

Last update:

November 1997 / First entry.


Technical section

PROSITE methods (with tools and information) covered by this documentation:

COF_1, PS01228; Hypothetical cof family signature 1  (PATTERN)

COF_2, PS01229; Hypothetical cof family signature 2  (PATTERN)


1AuthorsBairoch A. Rudd K.E.
SourceUnpublished observations (1996).

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