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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00193


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00193
General rule information [?]

Accession PRU00193
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 15)
Data class Domain;
Predictors PROSITE; PS50045; SIGMA54_INTERACT_4
Name Sigma-54 factor interaction domain
Function Undefined
Scope(s) Bacteria
Example(s) P41789;

Propagated annotation [?]

Keywords [?]

ATP-binding
Nucleotide-binding
Transcription
Transcription regulation

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0000166; Molecular function:nucleotide binding
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS00688; SIGMA54_INTERACT_3; 1;
PROSITE PS00676; SIGMA54_INTERACT_2; 1;
PROSITE PS00675; SIGMA54_INTERACT_1; 1;

Features [?]

From: PS50045
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Sigma-54 factor interaction #"
BINDING 29 36 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
BINDING 92 101 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

Additional information [?]

Size range 200-270 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]