ProRule PRU10097
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU10097 |
| Accession | PRU10097 |
| Dates | 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 10) |
| Data class | Domain; |
| Predictors |
Metamotif; -; PS00501~(PS00760){,1}~PS00761 |
Name | Signal peptidases I serine active sites |
| Function | Signal peptidases (SPases) (also known as leader peptidases) remove the signal peptides from secretory proteins. |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | Q5HHB9 (LEP_STAAC); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + AltName: Full=Signal peptidase I; EC=3.4.21.89; |
Comments
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| CATALYTIC ACTIVITY | Reaction=Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.; EC=3.4.21.89; |
Keywords
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Gene Ontology
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| GO:0016787; Molecular function:hydrolase activity |
| GO:0008233; Molecular function:peptidase activity |
Cross-references
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Features
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| From: PS00501 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 3 | 3 | ||||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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