PRU10097

General rule information [?]

Accession	PRU10097
Dates	16-OCT-2006 (Created) 22-NOV-2019 (Last updated, Version 10)

Data class

Domain

Predictors Metamotif; -; PS00501~(PS00760){,1}~PS00761

Name	Signal peptidases I serine active sites

Function

Signal peptidases (SPases) (also known as leader peptidases) remove the signal peptides from secretory proteins.

Propagated annotation [?]

Description [?]

+ AltName: Full=Signal peptidase I; EC 3.4.21.89;

Comments [?]

Catalytic activity

Reaction=Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.; EC=3.4.21.89;

Cross-references [?]

PROSITE	PS00501; SPASE_I_1; 1;
	PS00760; SPASE_I_2; 0-1;
	PS00761; SPASE_I_3; 1;

Gene Ontology [?]

GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.

Keywords [?]

Hydrolase
Protease

Features [?]

From: PS00501

Key From To Description Tag Condition FTGroup

ACT_SITE 3 3

From: PS00760

ACT_SITE 1 1

Additional information [?]

Size range	unlimited amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	Q5HHB9 (LEP_STAAC)
Scope	Eukaryota Bacteria

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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