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annotation rule: PRU10097

General rule information [?]

Accession PRU10097
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 10)
Data class Domain
Predictors Metamotif; -; PS00501~(PS00760){,1}~PS00761
Name Signal peptidases I serine active sites
Function Signal peptidases (SPases) (also known as leader peptidases) remove the signal peptides from secretory proteins.

Propagated annotation [?]


Description [?]

+ AltName: Full=Signal peptidase I; EC 3.4.21.89;

Comments [?]

Catalytic activity Reaction=Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.; EC=3.4.21.89;

Cross-references [?]

PROSITE PS00501; SPASE_I_1; 1;
PS00760; SPASE_I_2; 0-1;
PS00761; SPASE_I_3; 1;

Gene Ontology [?]

GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.

Keywords [?]


Features [?]

From: PS00501
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     3     3                
From: PS00760
ACT_SITE     1     1                

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q5HHB9 (LEP_STAAC)
Scope
Eukaryota
Bacteria

Copyright

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