ProRule PRU10097
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU10097
        General rule information
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    | Accession | PRU10097 | 
| Dates | 16-OCT-2006 (Created) 22-NOV-2019 (Last updated, Version 11) | 
| Data class | Domain; | 
| Predictors | Metamotif; -; PS00501~(PS00760){,1}~PS00761 | Name | Signal peptidases I serine active sites | 
| Function | Signal peptidases (SPases) (also known as leader peptidases) remove the signal peptides from secretory proteins. | 
| Scope(s) | Eukaryota Bacteria | 
| Example(s) | Q5HHB9 (LEP_STAAC); | 
        Propagated annotation
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        Identifier, protein and gene names
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    | Protein name | + AltName: Full=Signal peptidase I; EC=3.4.21.89; | 
        
        Comments
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    | CATALYTIC ACTIVITY | Reaction=Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.; EC=3.4.21.89; | 
    
    Keywords
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    Gene Ontology
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    | GO:0016787; Molecular function:hydrolase activity | 
| GO:0008233; Molecular function:peptidase activity | 
    
    Cross-references
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    Features
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    | From: PS00501 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 3 | 3 | ||||||||||
    
    Additional information
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    | Size range | unlimited amino acids | 
| Related rules | None | 
| Fusion | None | 
| Repeats | 1 | 
| Topology | Undefined | 
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