PROSITE documentation PDOC00588

Ribosomal protein L30e signatures

Description:

A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Mammalian L30 [1].
  • Leishmania major L30.
  • Yeast YL32 [2].
  • Bacillus subtilis hypothetical protein ybxF.
  • Thermococcus celer L30 [3].
  • A probable ribosomal protein (ORF 1) from Methanococcus vannielii [4].
  • A probable ribosomal protein (ORF 104) from Sulfolobus acidocaldarius [5].

These proteins have 82 to 114 amino-acid residues. As signature patterns, we selected two conserved regions; one located in the N-terminal region, the other in the C-terminal.

Last update:

April 2006 / Pattern revised.

Technical section:

PROSITE methods (with tools and information) covered by this documentation:

RIBOSOMAL_L30E_1, PS00709Ribosomal protein L30e signature 1  (PATTERN)
Consensus pattern: [STA]-x(5)-G-x-[QKRN]-x(2)-[LIVMQ]-[KRQT]-x(2)-[KR]-x-[GS]-x(2)-[KQ]-x-[LIVM](3)
Sequences known to belong to this class detected by the pattern: ALL
Other sequence(s) detected in Swiss-Prot: NONE.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00709
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00709
Scan Swiss-Prot/TrEMBL entries against PS00709
view ligand binding statistics
Matching PDB structures: 1CK2 1CN7 1GO0 1GO1 ... [ALL]
RIBOSOMAL_L30E_2, PS00993Ribosomal protein L30e signature 2  (PATTERN)
Consensus pattern: [DE]-[LM]-G-[STALPD]-x(2)-[GK]-[KR]-x(6)-[LIVM]-x-[LIVM]-x-[DEN]-x-[GI]
Sequences known to belong to this class detected by the pattern: ALL, except for Bacillus subtilis ybxF
Other sequence(s) detected in Swiss-Prot: NONE.
• Retrieve an alignment of Swiss-Prot true positive hits:
  Clustal format, color, condensed view  / Clustal format, color  / Clustal format, plain text  / Fasta format
Retrieve the sequence logo from the alignment
Taxonomic tree view of all Swiss-Prot/TrEMBL entries matching PS00993
Retrieve a list of all Swiss-Prot/TrEMBL entries matching PS00993
Scan Swiss-Prot/TrEMBL entries against PS00993
view ligand binding statistics
Matching PDB structures: 1CK2 1CN7 1GO0 1GO1 ... [ALL]

References:

1 AuthorsNakanishi O., Oyanagi M., Kuwano Y., Tanaka T., Nakayama T., Mitsui H., Nabeshima Y., Ogata K.
TitleMolecular cloning and nucleotide sequences of cDNAs specific for rat liver ribosomal proteins S17 and L30.
SourceGene 35:289-296(1985).
PubMed ID3840111
2 AuthorsDabeva M.D., Warner J.R.
TitleThe yeast ribosomal protein L32 and its gene.
SourceJ. Biol. Chem. 262:16055-16059(1987).
PubMed ID3316213
3 AuthorsKlenk H.-P., Schwass V., Zillig W.
TitleNucleotide sequence of the genes encoding the L30, S12 and S7 equivalent ribosomal proteins from the archaeum Thermococcus celer.
SourceNucleic Acids Res. 19:6047-6047(1991).
PubMed ID1840672
4 AuthorsLechner K., Heller G., Boeck A.
TitleOrganization and nucleotide sequence of a transcriptional unit of Methanococcus vannielii comprising genes for protein synthesis elongation factors and ribosomal proteins.
SourceJ. Mol. Evol. 29:20-27(1989).
PubMed ID2475640
5 AuthorsPuehler G., Lottspeich F., Zillig W.
SourceNucleic Acids Res. 17:4517-4534(1989).

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