|PROSITE documentation PDOC51048|
The SGT1-specific (SGS) domain is a module of ~90 amino acids, which was initially identified in eukaryotic SGT1 proteins . It was latter also found in calcyclin-binding proteins . The SGS domain has been shown to bind to proteins of the S100 family, which are thought to function as sensors of calcium ion concentration in the cell .
Some proteins known to contain a SGS domain are listed below:
The profile we developed covers the entire SGS domain.Last update:
December 2004 / First entry.
PROSITE method (with tools and information) covered by this documentation:
|1||Authors||Azevedo C., Sadanandom A., Kitagawa K., Freialdenhoven A., Shirasu K., Schulze-Lefert P.|
|Title||The RAR1 interactor SGT1, an essential component of R gene-triggered disease resistance.|
|2||Authors||Nowotny M., Spiechowicz M., Jastrzebska B., Filipek A., Kitagawa K., Kuznicki J.|
|Title||Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins.|
|Source||J. Biol. Chem. 278:26923-26928(2003).|