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annotation rule: PRU00121

General rule information [?]

Accession PRU00121
Dates 12-DEC-2003 (Created)
16-DEC-2016 (Last updated, Version 8)
Data class Domain
Predictors PROSITE; PS50070; KRINGLE_2
Name Kringle domain
Function Kringle domains are thought to play a role in binding mediators, such as membranes, other proteins or phospholipids, and in the regulation of proteolytic activity.

Propagated annotation [?]

Cross-references [?]


Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS50070
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Kringle #        
DISULFID     2     79           disulf   C-x*-C  
DISULFID     23     62           disulf   C-x*-C  
DISULFID     51     74           disulf   C-x*-C  

Additional information [?]

Size range 73-85 amino acids
Related rules None
Repeats 1-10
Topology Undefined
Example Q14520 (HABP2_HUMAN)
Scope Eukaryota; Metazoa


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.

UniProtKB rule member sequences [?]