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annotation rule: PRU00269

General rule information [?]

Accession PRU00269
Dates 12-DEC-2003 (Created)
16-DEC-2016 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS50290; PI3_4_KINASE_3
Name PI3K/PI4K domain
Function Phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring.

Propagated annotation [?]

Cross-references [?]

PROSITE PS00915; PI3_4_KINASE_1; 1;
PS00916; PI3_4_KINASE_2; 1;

Gene Ontology [?]

GO:0016740; Molecular function: transferase activity.
GO:0016301; Molecular function: kinase activity.

Keywords [?]

Features [?]

From: PS50290
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PI3K/PI4K #        

Additional information [?]

Size range 244-381 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P22543 (VPS34_YEAST)
Scope Eukaryota


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]