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annotation rule: PRU00280

General rule information [?]

Accession PRU00280
Dates 12-DEC-2003 (Created)
16-DEC-2016 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS50846; HMA_2
Name Heavy-metal-associated domain
Function Found in proteins that transport or detoxify heavy metals. This domain contains two conserved cysteines that could be involved in the binding of these metals.

Propagated annotation [?]

Cross-references [?]

PROSITE PS01047; HMA_1; 1;

Keywords [?]

case <FTGroup:1>
end case

Features [?]

From: PS50846
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       HMA #        
METAL     11     11             C   1
METAL     14     14             C   1

Additional information [?]

Size range 54-75 amino acids
Related rules None
Repeats 1-6
Topology Undefined
Example Q47840 (COPZ_ENTHA)
Scope Eukaryota


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.

UniProtKB rule member sequences [?]